4RVP
| Crystal structure of superoxide dismutase from sedum alfredii | Descriptor: | ZINC ION, superoxide dismutase | Authors: | Qiu, R, Li, C, Zhai, J, Tang, L, Zhang, H, Yuan, M, Hu, X. | Deposit date: | 2014-11-27 | Release date: | 2015-12-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The positive effects of Cd and Cd-Zn relationship in the
Zn-related physiological processes involved in growth in the Zn/Cd hyperaccumulator Sedum alfredii To be Published
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3ED0
| Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with emodin | Descriptor: | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, BENZAMIDINE, ... | Authors: | Zhang, L, Zhang, H, Liu, W, Guo, Y, Shen, X, Jiang, H. | Deposit date: | 2008-09-02 | Release date: | 2009-07-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Emodin targets the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: enzymatic inhibition assay with crystal structural and thermodynamic characterization BMC MICROBIOL., 9, 2009
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4MGJ
| Crystal structure of cytochrome P450 2B4 F429H in complex with 4-CPI | Descriptor: | 4-(4-CHLOROPHENYL)IMIDAZOLE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Yang, Y, Zhang, H, Usharani, D, Bu, W, Im, S, Tarasev, M, Rwere, F, Meagher, J, Sun, C, Stuckey, J, Shaik, S, Waskell, L. | Deposit date: | 2013-08-28 | Release date: | 2014-08-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structural and Functional Characterization of a Cytochrome P450 2B4 F429H Mutant with an Axial Thiolate-Histidine Hydrogen Bond. Biochemistry, 53, 2014
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4O5P
| Crystal structure of an uncharacterized protein from Pseudomonas aeruginosa | Descriptor: | Uncharacterized protein | Authors: | Hu, H.D, Gao, Z.Q, Zhang, H, Dong, Y.H. | Deposit date: | 2013-12-19 | Release date: | 2014-08-13 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structure of the type VI secretion phospholipase effector Tle1 provides insight into its hydrolysis and membrane targeting. Acta Crystallogr.,Sect.D, 70, 2014
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7LJC
| Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein | Descriptor: | (1R)-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, ... | Authors: | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | Deposit date: | 2021-01-28 | Release date: | 2021-03-03 | Last modified: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor. Cell Res., 31, 2021
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7LJD
| Allosteric modulator LY3154207 binding to dopamine-bound dopamine receptor 1 in complex with miniGs protein | Descriptor: | 2-[2,6-bis(chloranyl)phenyl]-1-[(1S,3R)-3-(hydroxymethyl)-1-methyl-5-(3-methyl-3-oxidanyl-butyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone, CHOLESTEROL, D(1A) dopamine receptor, ... | Authors: | Zhuang, Y, Krumm, B, Zhang, H, Zhou, X.E, Wang, Y, Guo, J, Huang, X.-P, Liu, Y, Wang, L, Cheng, X, Jiang, Y, Jiang, H, Melcher, K, Zhang, C, Yi, W, Roth, B.L, Zhang, Y, Xu, H.E. | Deposit date: | 2021-01-28 | Release date: | 2021-03-03 | Last modified: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor. Cell Res., 31, 2021
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4I8O
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4HZ9
| Crystal structure of the type VI native effector-immunity complex Tae3-Tai3 from Ralstonia pickettii | Descriptor: | Putative cytoplasmic protein, Putative periplasmic protein | Authors: | Dong, C, Zhang, H, Gao, Z.Q, Dong, Y.H. | Deposit date: | 2012-11-14 | Release date: | 2013-08-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3 Biochem.J., 454, 2013
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4HZB
| Crystal structure of the type VI SeMet effector-immunity complex Tae3-Tai3 from Ralstonia pickettii | Descriptor: | Putative cytoplasmic protein, Putative periplasmic protein | Authors: | Dong, C, Zhang, H, Gao, Z.Q, Dong, Y.H. | Deposit date: | 2012-11-15 | Release date: | 2013-08-21 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into the inhibition of type VI effector Tae3 by its immunity protein Tai3 Biochem.J., 454, 2013
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8WLD
| Cryo-EM structure of SIR2/HerA antiphage complex | Descriptor: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | Deposit date: | 2023-09-29 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Cryo-EM structure of SIR2/HerA antiphage complex To Be Published
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8WIV
| Cryo-EM structure of a bacterial protein | Descriptor: | Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | Deposit date: | 2023-09-25 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Cryo-EM structure of a bacterial protein To Be Published
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8WOC
| Cryo-EM structure of SIR2/HerA complex | Descriptor: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | Deposit date: | 2023-10-07 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.28 Å) | Cite: | Cryo-EM structure of a bacterial protein To Be Published
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8WOF
| Cryo-EM structure of SIR2/HerA complex | Descriptor: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | Deposit date: | 2023-10-07 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structure of a bacterial protein To Be Published
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8WOD
| Cryo-EM structure of SIR2/HerA complex | Descriptor: | Helicase HerA central domain-containing protein, SIR2-like domain-containing protein | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | Deposit date: | 2023-10-07 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Cryo-EM structure of a bacterial protein To Be Published
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8W9L
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8W9X
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8WJ3
| Cryo-EM structure of a bacterial protein | Descriptor: | Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | Deposit date: | 2023-09-25 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Cryo-EM structure of a bacterial protein To Be Published
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8WK0
| Cryo-EM structure of a bacterial protein | Descriptor: | Helicase HerA central domain-containing protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | Authors: | Yu, G, Liao, F, Li, X, Li, Z, Zhang, H. | Deposit date: | 2023-09-26 | Release date: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.34 Å) | Cite: | Cryo-EM structure of a bacterial protein To Be Published
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8YQF
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6LG4
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6LG8
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8HEF
| The Crystal structure of deuterated S-217622 (Ensitrelvir) bound to the main protease (3CLpro/Mpro) of SARS-CoV-2 | Descriptor: | 3C-like proteinase, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione, GLYCEROL | Authors: | Yan, M, Zhang, H. | Deposit date: | 2022-11-08 | Release date: | 2023-04-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Synthesis of deuterated S-217622 (Ensitrelvir) with antiviral activity against coronaviruses including SARS-CoV-2. Antiviral Res., 213, 2023
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5H14
| EED in complex with an allosteric PRC2 inhibitor EED666 | Descriptor: | 2-[3-(3,5-dimethylpyrazol-1-yl)-4-nitro-phenyl]-3,4-dihydro-1H-isoquinoline, GLYCEROL, Histone-lysine N-methyltransferase EZH2, ... | Authors: | Zhao, K, Zhao, M, Luo, X, Zhang, H. | Deposit date: | 2016-10-08 | Release date: | 2017-01-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED PLoS ONE, 12, 2017
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5H15
| EED in complex with PRC2 allosteric inhibitor EED709 | Descriptor: | (3R,4S)-1-[(2-methoxyphenyl)methyl]-N,N-dimethyl-4-(1-methylindol-3-yl)pyrrolidin-3-amine, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED | Authors: | Zhao, K, Zhao, M, Luo, X, Zhang, H. | Deposit date: | 2016-10-08 | Release date: | 2017-01-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED PLoS ONE, 12, 2017
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5H13
| EED in complex with PRC2 allosteric inhibitor EED396 | Descriptor: | 4-azanylidene-2-(3-methoxy-4-propan-2-yloxy-phenyl)-6,7-dihydro-[1,3]benzodioxolo[6,5-a]quinolizine-3-carbonitrile, GLYCEROL, PRASEODYMIUM ION, ... | Authors: | Zhao, K, Zhao, M, Luo, X, Zhang, H. | Deposit date: | 2016-10-08 | Release date: | 2017-01-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED PLoS ONE, 12, 2017
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