4MGJ
Crystal structure of cytochrome P450 2B4 F429H in complex with 4-CPI
Summary for 4MGJ
Entry DOI | 10.2210/pdb4mgj/pdb |
Related | 4MGL 4MGO |
Descriptor | Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE, 4-(4-CHLOROPHENYL)IMIDAZOLE, ... (4 entities in total) |
Functional Keywords | p450 fold, closed conformation, 4-cpi binding, oxidoreductase |
Biological source | Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P00178 |
Total number of polymer chains | 1 |
Total formula weight | 54965.19 |
Authors | Yang, Y.,Zhang, H.,Usharani, D.,Bu, W.,Im, S.,Tarasev, M.,Rwere, F.,Meagher, J.,Sun, C.,Stuckey, J.,Shaik, S.,Waskell, L. (deposition date: 2013-08-28, release date: 2014-08-13, Last modification date: 2024-02-28) |
Primary citation | Yang, Y.,Zhang, H.,Usharani, D.,Bu, W.,Im, S.,Tarasev, M.,Rwere, F.,Pearl, N.M.,Meagher, J.,Sun, C.,Stuckey, J.,Shaik, S.,Waskell, L. Structural and Functional Characterization of a Cytochrome P450 2B4 F429H Mutant with an Axial Thiolate-Histidine Hydrogen Bond. Biochemistry, 53:5080-5091, 2014 Cited by PubMed: 25029089DOI: 10.1021/bi5003794 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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