4MGJ
Crystal structure of cytochrome P450 2B4 F429H in complex with 4-CPI
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cytochrome P450 2B4 | polymer | 476 | 54170.1 | 1 | UniProt (P00178) Pfam (PF00067) In PDB | Oryctolagus cuniculus (European rabbit Japanese white rabbit domestic rabbit rabbits) | CYPIIB4, Cytochrome P450 isozyme 2, Cytochrome P450 LM2, Cytochrome P450 type B0, Cytochrome P450 type B1 |
2 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
3 | A | 4-(4-CHLOROPHENYL)IMIDAZOLE | non-polymer | 178.6 | 1 | Chemie (CPZ) | |||
4 | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 30 - 491 (UniProt: P00178)
PDB | External Database | Details |
---|---|---|
Met 20 | - | initiating methionine |
Ala 21 | - | expression tag |
Lys 22 | - | expression tag |
Lys 23 | - | expression tag |
Thr 24 | - | expression tag |
Ser 25 | - | expression tag |
Ser 26 | - | expression tag |
Lys 27 | - | expression tag |
Gly 28 | - | expression tag |
Lys 29 | - | expression tag |
Tyr 226 | His 226 | engineered mutation |
His 429 | Phe 429 | engineered mutation |
His 492 | - | expression tag |
His 493 | - | expression tag |
His 494 | - | expression tag |
His 495 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 54170.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 795.1 | |
All* | Total formula weight | 54965.2 |