4MGJ
Crystal structure of cytochrome P450 2B4 F429H in complex with 4-CPI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cytochrome P450 2B4 | polymer | 476 | 54170.1 | 1 | UniProt (P00178) Pfam (PF00067) | Oryctolagus cuniculus (European rabbit Japanese white rabbit domestic rabbit rabbits) | CYPIIB4, Cytochrome P450 isozyme 2, Cytochrome P450 LM2, Cytochrome P450 type B0, Cytochrome P450 type B1 |
| 2 | B (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 3 | C (A) | 4-(4-CHLOROPHENYL)IMIDAZOLE | non-polymer | 178.6 | 1 | Chemie (CPZ) | |||
| 4 | D (A) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 30 - 491 (UniProt: P00178)
| PDB | External Database | Details |
|---|---|---|
| Met 20 | - | initiating methionine |
| Ala 21 | - | expression tag |
| Lys 22 | - | expression tag |
| Lys 23 | - | expression tag |
| Thr 24 | - | expression tag |
| Ser 25 | - | expression tag |
| Ser 26 | - | expression tag |
| Lys 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Lys 29 | - | expression tag |
| Tyr 226 | His 226 | engineered mutation |
| His 429 | Phe 429 | engineered mutation |
| His 492 | - | expression tag |
| His 493 | - | expression tag |
| His 494 | - | expression tag |
| His 495 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54170.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 795.1 | |
| All* | Total formula weight | 54965.2 |
