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4MSD
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BU of 4msd by Molmil
Crystal structure of Schizosaccharomyces pombe AMSH-like protein SST2 T319I mutant
Descriptor: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, AMSH-like protease sst2, ...
Authors:Shrestha, R.K, Ronau, J.A, Das, C.
Deposit date:2013-09-18
Release date:2014-06-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.
Biochemistry, 53, 2014
4P6I
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BU of 4p6i by Molmil
Crystal structure of the Cas1-Cas2 complex from Escherichia coli
Descriptor: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2
Authors:Nunez, J.K, Kranzusch, P.J, Noeske, J, Doudna, J.A.
Deposit date:2014-03-24
Release date:2014-05-07
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity.
Nat.Struct.Mol.Biol., 21, 2014
7LM3
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BU of 7lm3 by Molmil
Crystal Structure of Thr316Ala mutant of JAMM domain of S. pombe
Descriptor: AMSH-like protease sst2, PHOSPHATE ION, ZINC ION
Authors:Shrestha, R, Das, C.
Deposit date:2021-02-05
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Thr316Ala mutant of a yeast JAMM deubiquitinase: implication of active-site loop dynamics in catalysis.
Acta Crystallogr.,Sect.F, 77, 2021
7SWD
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BU of 7swd by Molmil
Structure of EBOV GP lacking the mucin-like domain with 1C11 scFv and 1C3 Fab bound
Descriptor: 1C11 scFv, 1C3 heavy chain, 1C3 light chain, ...
Authors:Milligan, J.C, Yu, X, Saphire, E.O.
Deposit date:2021-11-19
Release date:2022-04-06
Last modified:2022-08-10
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses.
Cell, 185, 2022
7U0P
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BU of 7u0p by Molmil
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-S21F2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Patel, A, Ortlund, E.
Deposit date:2022-02-18
Release date:2022-08-10
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (3.76 Å)
Cite:Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody.
Sci Adv, 8, 2022
7U0Q
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BU of 7u0q by Molmil
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-02
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Patel, A, Ortlund, E.
Deposit date:2022-02-18
Release date:2023-03-01
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.86 Å)
Cite:Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
Structure, 31, 2023
7U0X
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BU of 7u0x by Molmil
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-13
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Patel, A, Ortlund, E.
Deposit date:2022-02-19
Release date:2023-03-01
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.82 Å)
Cite:Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
Structure, 31, 2023
7UPL
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BU of 7upl by Molmil
SARS-Cov2 Omicron varient S protein structure in complex with neutralizing monoclonal antibody 002-S21F2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Patel, A, Ortlund, E.
Deposit date:2022-04-15
Release date:2022-08-10
Last modified:2023-02-22
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody.
Sci Adv, 8, 2022
7UOW
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BU of 7uow by Molmil
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 034_32
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal antibody 034_32 heavy chain, ...
Authors:Patel, A, Ortlund, E.
Deposit date:2022-04-14
Release date:2023-04-19
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
Structure, 31, 2023
8GDR
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BU of 8gdr by Molmil
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-S21B10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal antibody 002-S21B10 heavy chain variable domain, ...
Authors:Patel, A, Ortlund, E.A.
Deposit date:2023-03-06
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Elucidating the mechanism of SARS-CoV-2 Omicron variant escape from a RBD class-3 human antibody
To Be Published
8DPM
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BU of 8dpm by Molmil
Structure of EBOV GP lacking the mucin-like domain with 9.20.1A2 Fab and 6D6 scFv bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 6D6 scFv, Antibody 9.20.1A2 Fab heavy chain, ...
Authors:Yu, X, Saphire, E.O.
Deposit date:2022-07-15
Release date:2023-07-19
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (3 Å)
Cite:The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus.
Cell Rep, 42, 2023
8DPL
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BU of 8dpl by Molmil
Structure of EBOV GP lacking the mucin-like domain with 2.1.1D5 scFv and 6D6 scFv bound
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2.1.1D5 heavy chain variable domain, 2.1.1D5 light chain variable domain, ...
Authors:Yu, X, Saphire, E.O.
Deposit date:2022-07-15
Release date:2023-07-19
Last modified:2023-11-22
Method:ELECTRON MICROSCOPY (2.53 Å)
Cite:The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus.
Cell Rep, 42, 2023
7N6P
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BU of 7n6p by Molmil
Crystal structure of the anti-EBOV and SUDV monoclonal antibody 1C3 Fab
Descriptor: 1C3 Fab heavy chain, 1C3 Fab light chain
Authors:Milligan, J.C, Yu, X, Buck, T, Saphire, E.O.
Deposit date:2021-06-08
Release date:2022-04-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses.
Cell, 185, 2022
7RPU
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BU of 7rpu by Molmil
Crystal Structure of Protective Human Antibody 3A6 Fab Against Ebola Virus with GP Stalk/MPER Epitope Peptide
Descriptor: 3A6 Fab heavy chain, 3A6 Fab light chain, GP2 epitope peptide
Authors:Salie, Z.L, Saphire, E.O, Davis, C.W, Ahmed, R.
Deposit date:2021-08-04
Release date:2022-07-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Protection against Ebola virus disease and neutralization mechanism of a survivor's anti-stalk-MPER antibody
To Be Published
7RPT
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BU of 7rpt by Molmil
Crystal Structure of Protective Human Antibody 3A6 Fab Against Ebola Virus
Descriptor: 3A6 Fab heavy chain, 3A6 Fab light chain
Authors:Salie, Z.L, Saphire, E.O, Davis, C.W, Ahmed, R.
Deposit date:2021-08-04
Release date:2022-07-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Protection against Ebola virus disease and neutralization mechanism of a survivor's anti-stalk/MPER antibody
To Be Published
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