7UOW

SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 034_32

Summary for 7UOW

Entry DOI	10.2210/pdb7uow/pdb
EMDB information	26656
Descriptor	Spike glycoprotein, Monoclonal antibody 034_32 heavy chain, Monoclonal antibody 034_32 light chain, ... (5 entities in total)
Functional Keywords	sars-cov2 6p spike protein, immune complex, viral protein
Biological source	Severe acute respiratory syndrome coronavirus More
Total number of polymer chains	7
Total formula weight	555716.19
Authors	Patel, A.,Ortlund, E. (deposition date: 2022-04-14, release date: 2023-04-19, Last modification date: 2023-09-13)
Primary citation	Patel, A.,Kumar, S.,Lai, L.,Chakravarthy, C.,Valanparambil, R.,Reddy, E.S.,Gottimukkala, K.,Bajpai, P.,Raju, D.R.,Edara, V.V.,Davis-Gardner, M.E.,Linderman, S.,Dixit, K.,Sharma, P.,Mantus, G.,Cheedarla, N.,Verkerke, H.P.,Frank, F.,Neish, A.S.,Roback, J.D.,Davis, C.W.,Wrammert, J.,Ahmed, R.,Suthar, M.S.,Sharma, A.,Murali-Krishna, K.,Chandele, A.,Ortlund, E.A. Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response. Structure, 31:801-811.e5, 2023 Cited by PubMed: 37167972 DOI: 10.1016/j.str.2023.04.010 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.4 Å)

Structure validation