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8GDR

SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-S21B10

Summary for 8GDR
Entry DOI10.2210/pdb8gdr/pdb
Related8GDR
EMDB information29950
DescriptorSpike glycoprotein, Monoclonal antibody 002-S21B10 heavy chain variable domain, Monoclonal antibody 002-S21B10 light chain variable domain, ... (5 entities in total)
Functional Keywordsantibody, spike, sars-cov-2, viral protein-immune system complex, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
More
Total number of polymer chains7
Total formula weight488138.73
Authors
Patel, A.,Ortlund, E.A. (deposition date: 2023-03-06, release date: 2024-03-13)
Primary citationPatel, A.,Kumar, S.,Lai, L.,Chakravarthy, C.,Valanparambil, R.,Keen, M.,Laughlin, Z.T.,Frank, F.,Cheedarla, N.,Verkerke, H.P.,Neish, A.S.,Roback, J.D.,Davis, C.W.,Wrammert, J.,Ahmed, R.,Suthar, M.S.,Murali-Krishna, K.,Chandele, A.,Ortlund, E.A.
Elucidating the mechanism of SARS-CoV-2 Omicron variant escape from a RBD class-3 human antibody
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.6 Å)
Structure validation

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