8GDR
SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-S21B10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, E (A, E, F) | Spike glycoprotein | polymer | 1168 | 128766.0 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | S glycoprotein,E2,Peplomer protein |
| 2 | B, F (C, H) | Monoclonal antibody 002-S21B10 heavy chain variable domain | polymer | 224 | 24113.3 | 2 | Homo sapiens (human) | ||
| 3 | C, G (D, J) | Monoclonal antibody 002-S21B10 light chain variable domain | polymer | 216 | 22861.3 | 2 | Homo sapiens (human) | ||
| 4 | H, I, J, K (c, e, g, i) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 5 | AA, BA, CA, DA, EA... (E, F, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 28 | Chemie (NAG) |
Sequence modifications
A, E, F: 14 - 1149 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Gly -17 | - | expression tag |
| Ile -16 | - | expression tag |
| Leu -15 | - | expression tag |
| Pro -14 | - | expression tag |
| Ser -13 | - | expression tag |
| Pro -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Met -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Ala -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Val -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Val 2 | - | expression tag |
| Leu 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Met 5 | - | expression tag |
| Gly 6 | - | expression tag |
| Cys 7 | - | expression tag |
| Val 8 | - | expression tag |
| Ala 9 | - | expression tag |
| Glu 10 | - | expression tag |
| Thr 11 | - | expression tag |
| Gly 12 | - | expression tag |
| Thr 13 | - | expression tag |
| Ser 682 | Arg 682 | conflict |
| Gly 683 | Arg 683 | conflict |
| Gly 685 | Arg 685 | conflict |
| Pro 817 | Phe 817 | conflict |
| Pro 892 | Ala 892 | conflict |
| Pro 899 | Ala 899 | conflict |
| Pro 942 | Ala 942 | conflict |
| Pro 986 | Lys 986 | conflict |
| Pro 987 | Val 987 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 480247.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 6193.8 | |
| All* | Total formula weight | 488138.7 |
