1S0X
 
 | | Crystal structure of the human RORalpha ligand binding domain in complex with cholesterol sulfate at 2.2A | | Descriptor: | CHOLEST-5-EN-3-YL HYDROGEN SULFATE, Nuclear receptor ROR-alpha | | Authors: | Kallen, J, Schlaeppi, J.M, Bitsch, F, Delhon, I, Fournier, B. | | Deposit date: | 2004-01-05 | | Release date: | 2004-02-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A
J.Biol.Chem., 279, 2004
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2IWR
 | | Gtpase Like Domain Of Centaurin Gamma 1 (Human) | | Descriptor: | CENTAURIN GAMMA 1 | | Authors: | Elkins, J.M, Soundararajan, M, Yang, X, Papagrigoriou, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-07-03 | | Release date: | 2006-07-04 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The Centaurin Gamma-1 Gtpase-Like Domain Functions as an Ntpase.
Biochem.J., 401, 2007
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2IWO
 | | 12th PDZ domain of Multiple PDZ Domain Protein MPDZ | | Descriptor: | MULTIPLE PDZ DOMAIN PROTEIN | | Authors: | Elkins, J.M, Yang, X, Gileadi, C, Schoch, G, Johansson, C, Savitsky, P, Berridge, G, Smee, C.E.A, Turnbull, A, Pike, A, Papagrigoriou, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A. | | Deposit date: | 2006-07-03 | | Release date: | 2006-07-26 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extensions.
Protein Sci., 16, 2007
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2IWP
 | | 12th PDZ domain of Multiple PDZ Domain Protein MPDZ | | Descriptor: | MULTIPLE PDZ DOMAIN PROTEIN | | Authors: | Elkins, J.M, Yang, X, Gileadi, C, Schoch, G, Johansson, C, Savitsky, P, Berridge, G, Smee, C.E.A, Turnbull, A, Pike, A, Papagrigoriou, E, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D.A. | | Deposit date: | 2006-07-03 | | Release date: | 2006-07-26 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structure of Pick1 and Other Pdz Domains Obtained with the Help of Self-Binding C-Terminal Extension.
Protein Sci., 16, 2007
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1SH2
 | | Crystal Structure of Norwalk Virus Polymerase (Metal-free, Centered Orthorhombic) | | Descriptor: | RNA Polymerase | | Authors: | Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F. | | Deposit date: | 2004-02-24 | | Release date: | 2004-03-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft.
J.Biol.Chem., 279, 2004
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2J7N
 | | Structure of the RNAi polymerase from Neurospora crassa | | Descriptor: | GLYCEROL, MAGNESIUM ION, RNA-DEPENDENT RNA POLYMERASE | | Authors: | Salgado, P.S, Koivunen, M.R.L, Makeyev, E.V, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | Deposit date: | 2006-10-13 | | Release date: | 2006-12-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Structure of an Rnai Polymerase Links RNA Silencing and Transcription.
Plos Biol., 4, 2006
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2IVI
 | | Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- methyl-cyclopropylglycine Fe Complex) | | Descriptor: | D-(L-A-AMINOADIPOYL)-L-CYSTEINYL-B-METHYL-D-CYCLOPROPYLGLYCINE, FE (II) ION, ISOPENICILLIN N SYNTHETASE, ... | | Authors: | Elkins, J.M, Howard-Jones, A.R, Clifton, I.J, Roach, P.L, Adlington, R.M, Baldwin, J.E, Rutledge, P.J. | | Deposit date: | 2006-06-13 | | Release date: | 2007-04-10 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Interactions of Isopenicillin N Synthase with Cyclopropyl-Containing Substrate Analogues Reveal New Mechanistic Insight.
Biochemistry, 46, 2007
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2J7O
 | | STRUCTURE OF THE RNAI POLYMERASE FROM NEUROSPORA CRASSA | | Descriptor: | MAGNESIUM ION, RNA DEPENDENT RNA POLYMERASE | | Authors: | Salgado, P.S, Koivunen, M.R.L, Makeyev, E.V, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | Deposit date: | 2006-10-13 | | Release date: | 2006-12-13 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The Structure of an Rnai Polymerase Links RNA Silencing and Transcription.
Plos Biol., 4, 2006
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1BDK
 | | AN NMR, CD, MOLECULAR DYNAMICS, AND FLUOROMETRIC STUDY OF THE CONFORMATION OF THE BRADYKININ ANTAGONIST B-9340 IN WATER AND IN AQUEOUS MICELLAR SOLUTIONS | | Descriptor: | bradykinin antagonist B-9340 | | Authors: | Sejbal, J, Kotovych, G, Cann, J.R, Stewart, J.M, Gera, L. | | Deposit date: | 1995-07-28 | | Release date: | 1995-12-07 | | Last modified: | 2024-06-05 | | Method: | SOLUTION NMR | | Cite: | An NMR, CD, molecular dynamics, and fluorometric study of the conformation of the bradykinin antagonist B-9340 in water and in aqueous micellar solutions.
J.Med.Chem., 39, 1996
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1R20
 | | Crystal structure of the ligand-binding domains of the heterodimer EcR/USP bound to the synthetic agonist BYI06830 | | Descriptor: | ECDYSONE RECEPTOR, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, N-(TERT-BUTYL)-3,5-DIMETHYL-N'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE, ... | | Authors: | Billas, I.M.L, Iwema, T, Garnier, J.M, Mitschler, A, Rochel, N, Moras, D, Structural Proteomics in Europe (SPINE) | | Deposit date: | 2003-09-25 | | Release date: | 2003-11-18 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.
Nature, 426, 2003
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1BIW
 | | DESIGN AND SYNTHESIS OF CONFORMATIONALLY-CONSTRAINED MMP INHIBITORS | | Descriptor: | CALCIUM ION, N1-HYDROXY-2-(3-HYDROXY-PROPYL)-3-ISOBUTYL-N4-[1-(2-METHOXY-ETHYL)-2-OXO-AZEPAN-3-YL]-SUCCINAMIDE, PROTEIN (STROMELYSIN-1 COMPLEX), ... | | Authors: | Natchus, M.G, Cheng, M, Wahl, C.T, Pikul, S, Almstead, N.G, Bradley, R.S, Taiwo, Y.O, Mieling, G.E, Dunaway, C.M, Snider, C.E, McIver, J.M, Barnett, B.L, McPhail, S.J, Anastasio, M.B, De, B. | | Deposit date: | 1998-06-19 | | Release date: | 1999-07-16 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Design and synthesis of conformationally-constrained MMP inhibitors.
Bioorg.Med.Chem.Lett., 8, 1998
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2J8P
 | | NMR structure of C-terminal domain of human CstF-64 | | Descriptor: | CLEAVAGE STIMULATION FACTOR 64 KDA SUBUNIT | | Authors: | Qu, X, Perez-Canadillas, J.M, Agrawal, S, De Baecke, J, Cheng, H, Varani, G, Moore, C. | | Deposit date: | 2006-10-27 | | Release date: | 2006-11-06 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The C-Terminal Domains of Vertebrate Cstf-64 and its Yeast Orthologue RNA15 Form a New Structure Critical for Mrna 3'-End Processing.
J.Biol.Chem., 282, 2007
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1BWT
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1BY8
 | | THE CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN K | | Descriptor: | PROTEIN (PROCATHEPSIN K) | | Authors: | Lalonde, J.M, Zhao, B, Smith, W.W, Janson, C.A, Desjarlais, R.L, Tomaszek, T.A, Carr, T.J, Thompson, S.K, Yamashita, D.S, Veber, D.F, Abdel-Mequid, S.S. | | Deposit date: | 1998-10-27 | | Release date: | 1999-10-24 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The crystal structure of human procathepsin K.
Biochemistry, 38, 1999
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1RHL
 | | RIBONUCLEASE T1 COMPLEXED WITH 2'GMP/G23A MUTANT | | Descriptor: | CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1) | | Authors: | Huyghues-Despointes, B.M.P, Langhorst, U, Steyaert, J, Pace, C.N, Scholtz, J.M. | | Deposit date: | 1998-10-09 | | Release date: | 1998-10-14 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Hydrogen-exchange stabilities of RNase T1 and variants with buried and solvent-exposed Ala --> Gly mutations in the helix.
Biochemistry, 38, 1999
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2JEQ
 | | Family 5 xyloglucanase from Paenibacillus pabuli in complex with ligand | | Descriptor: | XYLOGLUCANASE, beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[beta-D-galactopyranose-(1-2)-alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Gloster, T.M, Ibatullin, F.M, Macauley, K, Eklof, J.M, Roberts, S, Turkenburg, J.P, Bjornvad, M.E, Jorgensen, P.L, Danielsen, S, Johansen, K, Borchert, T.V, Wilson, K.S, Brumer, H, Davies, G.J. | | Deposit date: | 2007-01-18 | | Release date: | 2007-03-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Characterization and Three-Dimensional Structures of Two Distinct Bacterial Xyloglucanases from Families Gh5 and Gh12.
J.Biol.Chem., 282, 2007
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2JBY
 | | A viral protein unexpectedly mimics the structure and function of pro- survival Bcl-2 | | Descriptor: | BCL-2 HOMOLOGOUS ANTAGONIST/KILLER 2, M11L PROTEIN, SODIUM ION | | Authors: | Kvansakul, M, Van Delft, M.F, Lee, E.F, Gulbis, J.M, Fairlie, W.D, Huang, D.C.S, Colman, P.M. | | Deposit date: | 2006-12-14 | | Release date: | 2007-03-27 | | Last modified: | 2018-06-13 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.
Mol. Cell, 25, 2007
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2INE
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2IJR
 | | Crystal structure of a protein api92 from Yersinia pseudotuberculosis, Pfam DUF1281 | | Descriptor: | Hypothetical protein api92 | | Authors: | Jin, X, Min, T, Bonanno, J.B, Sauder, J.M, Wasserman, S, Smith, D, Burley, S.K, Shapiro, L, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2006-09-30 | | Release date: | 2006-10-31 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of a hypothetical protein from Yersinia
pseudotuberculosis
To be Published
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2IML
 | | Crystal structure of a hypothetical protein from Archaeoglobus fulgidus binding riboflavin 5'-phosphate | | Descriptor: | FLAVIN MONONUCLEOTIDE, GLYCEROL, Hypothetical protein | | Authors: | Bonanno, J.B, Dickey, M, Bain, K.T, Adams, J, Ozyurt, S, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2006-10-04 | | Release date: | 2006-10-17 | | Last modified: | 2021-02-03 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of a hypothetical protein from
Archaeoglobus fulgidus binding riboflavin 5'-phosphate
To be Published
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1U86
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2ICP
 | | Crystal structure of the bacterial antitoxin HigA from Escherichia coli at pH 4.0. Northeast Structural Genomics Consortium TARGET ER390. | | Descriptor: | MAGNESIUM ION, antitoxin higa | | Authors: | Arbing, M.A, Abashidze, M, Hurley, J.M, Zhao, L, Janjua, H, Cunningham, K, Ma, L.C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Inouye, M, Woychik, N.A, Montelione, G.T, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-09-13 | | Release date: | 2006-09-26 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Crystal structure of the bacterial antitoxin HigA from Escherichia coli.
To be Published
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1BMB
 | | GRB2-SH2 DOMAIN IN COMPLEX WITH KPFY*VNVEF (PKF270-974) | | Descriptor: | PROTEIN (GROWTH FACTOR RECEPTOR BOUND PROTEIN 2), PROTEIN (PKF270-974) | | Authors: | Rondeau, J.M, Zurini, M. | | Deposit date: | 1998-07-23 | | Release date: | 1998-07-29 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1).
J.Med.Chem., 42, 1999
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1UCL
 | | Mutants of RNase Sa | | Descriptor: | Guanyl-specific ribonuclease Sa, SULFATE ION | | Authors: | Takano, K, Scholtz, J.M, Sacchettini, J.C, Pace, C.N. | | Deposit date: | 2003-04-15 | | Release date: | 2003-09-09 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | The contribution of polar group burial to protein stability is strongly context-dependent
J.Biol.Chem., 278, 2003
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1TOG
 | | Hydrocinnamic acid-bound structure of SRHEPT + A293D mutant of E. coli aspartate aminotransferase | | Descriptor: | Aspartate aminotransferase, HYDROCINNAMIC ACID | | Authors: | Chow, M.A, McElroy, K.E, Corbett, K.D, Berger, J.M, Kirsch, J.F. | | Deposit date: | 2004-06-14 | | Release date: | 2004-10-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase
Biochemistry, 43, 2004
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