1TOG

Hydrocinnamic acid-bound structure of SRHEPT + A293D mutant of E. coli aspartate aminotransferase

Summary for 1TOG

• Entry DOI: 10.2210/pdb1tog/pdb
• Related: 1TOE
• Descriptor: Aspartate aminotransferase, HYDROCINNAMIC ACID (3 entities in total)
• Functional Keywords: aspartate aminotransferase hexamutant, srhept, transferase
• Biological source: Escherichia coli
• Cellular location: Cytoplasm: P00509
• Total number of polymer chains: 2
• Total formula weight: 88038.93

Authors

Chow, M.A.,McElroy, K.E.,Corbett, K.D.,Berger, J.M.,Kirsch, J.F. (deposition date: 2004-06-14, release date: 2004-10-05, Last modification date: 2023-11-15)

• Primary citation: Chow, M.A.,McElroy, K.E.,Corbett, K.D.,Berger, J.M.,Kirsch, J.F.; Narrowing substrate specificity in a directly evolved enzyme: the A293D mutant of aspartate aminotransferase; Biochemistry, 43:12780-12787, 2004; PubMed: 15461450; DOI: 10.1021/bi0487544

Experimental method

X-RAY DIFFRACTION (2.31 Å)