2IVI

Isopenicillin N Synthase From Aspergillus Nidulans (Anaerobic Ac- methyl-cyclopropylglycine Fe Complex)

Summary for 2IVI

Entry DOI	10.2210/pdb2ivi/pdb
Related	1BK0 1BLZ 1HB1 1HB2 1HB3 1HB4 1IPS 1OBN 1OC1 1ODM 1ODN 1QIQ 1QJE 1QJF 1UZW 1W03 1W04 1W05 1W06 1W3V 1W3X 2BJS 2BU9 2IVJ
Descriptor	ISOPENICILLIN N SYNTHETASE, D-(L-A-AMINOADIPOYL)-L-CYSTEINYL-B-METHYL-D-CYCLOPROPYLGLYCINE, SULFATE ION, ... (5 entities in total)
Functional Keywords	antbiotic biosynthesis, antibiotic biosynthesis, iron, oxygenase, vitamin c, metal-binding, penicillin biosynthesis, oxidoreductase, b-lactam antibiotic
Biological source	EMERICELLA NIDULANS
Total number of polymer chains	1
Total formula weight	38187.25
Authors	Elkins, J.M.,Howard-Jones, A.R.,Clifton, I.J.,Roach, P.L.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. (deposition date: 2006-06-13, release date: 2007-04-10, Last modification date: 2014-02-19)
Primary citation	Howard-Jones, A.R.,Elkins, J.M.,Clifton, I.J.,Roach, P.L.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. Interactions of Isopenicillin N Synthase with Cyclopropyl-Containing Substrate Analogues Reveal New Mechanistic Insight. Biochemistry, 46:4755-, 2007 Cited by PubMed: 17397141 DOI: 10.1021/BI062314Q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation