1W3X

Isopenicillin N synthase d-(L-a-aminoadipoyl)-(3R)-methyl-L-cysteine D-a-hydroxyisovaleryl ester complex (Oxygen exposed 5 minutes 20 bar)

Summary for 1W3X

Entry DOI	10.2210/pdb1w3x/pdb
Related	1BK0 1BLZ 1HB1 1HB2 1HB3 1HB4 1IPS 1OBN 1OC1 1ODM 1ODN 1QIQ 1QJE 1QJF 1UZW 1W03 1W04 1W05 1W06 1W3V 2BJS 2BU9
Descriptor	ISOPENICILLIN N SYNTHETASE, FE (II) ION, N~6~-[(1R)-1-({[(1R,2R)-1-CARBOXY-3-HYDROXY-2-METHYLPROPYL]OXY}CARBONYL)-2-MERCAPTOPROP-2-EN-1-YL]-6-OXO-L-LYSINE, ... (4 entities in total)
Functional Keywords	synthase, antibiotic biosynthesis, b-lactam antibiotic, iron, oxidoreductase, oxygenase, penicillin biosynthesis
Biological source	EMERICELLA NIDULANS
Total number of polymer chains	1
Total formula weight	38012.11
Authors	Daruzzaman, A.,Clifton, I.J.,Rutledge, P.J. (deposition date: 2004-07-20, release date: 2005-12-07, Last modification date: 2023-12-13)
Primary citation	Daruzzaman, A.,Clifton, I.J.,Adlington, R.M.,Baldwin, J.E.,Rutledge, P.J. Unexpected Oxidation of a Depsipeptide Substrate Analogue in Crystalline Isopenicillin N Synthase. Chembiochem, 7:351-, 2006 Cited by PubMed: 16444759 DOI: 10.1002/CBIC.200500282 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.46 Å)

Structure validation