6GYW
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6GYY
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6GYX
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4DT0
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3G5Q
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![BU of 3g5q by Molmil](/molmil-images/mine/3g5q) | Crystal structure of Thermus thermophilus TrmFO | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, FLAVIN-ADENINE DINUCLEOTIDE, Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase trmFO | Authors: | Nishimasu, H, Ishitani, R, Hori, H, Nureki, O. | Deposit date: | 2009-02-05 | Release date: | 2009-05-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.102 Å) | Cite: | Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase Proc.Natl.Acad.Sci.USA, 106, 2009
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3G5R
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![BU of 3g5r by Molmil](/molmil-images/mine/3g5r) | Crystal structure of Thermus thermophilus TrmFO in complex with tetrahydrofolate | Descriptor: | (6S)-5,6,7,8-TETRAHYDROFOLATE, 1,2-ETHANEDIOL, CALCIUM ION, ... | Authors: | Nishimasu, H, Ishitani, R, Hori, H, Nureki, O. | Deposit date: | 2009-02-05 | Release date: | 2009-05-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase Proc.Natl.Acad.Sci.USA, 106, 2009
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3G5S
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![BU of 3g5s by Molmil](/molmil-images/mine/3g5s) | Crystal structure of Thermus thermophilus TrmFO in complex with glutathione | Descriptor: | 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, ... | Authors: | Nishimasu, H, Ishitani, R, Hori, H, Nureki, O. | Deposit date: | 2009-02-05 | Release date: | 2009-05-19 | Last modified: | 2011-12-14 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase Proc.Natl.Acad.Sci.USA, 106, 2009
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2GS9
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![BU of 2gs9 by Molmil](/molmil-images/mine/2gs9) | Crystal structure of TT1324 from Thermus thermophilis HB8 | Descriptor: | FORMIC ACID, Hypothetical protein TT1324, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Kamitori, S, Abe, A, Ebihara, A, Kanagawa, M, Nakagawa, N, Kuroishi, C, Agari, Y, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-04-25 | Release date: | 2007-03-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of TT1324 from Thermus thermophilis HB8 To be Published
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7OJR
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7OJS
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7OML
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7OLH
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4X6Y
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4X6X
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![BU of 4x6x by Molmil](/molmil-images/mine/4x6x) | Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative | Descriptor: | 3-{4-[(1-{[(1s,2R,3S)-2,3-diphenylcyclopropyl]carbamoyl}piperidin-4-yl)oxy]phenyl}propanoic acid, Bifunctional epoxide hydrolase 2 | Authors: | Chiyo, N, Takai, K, Ishii, T. | Deposit date: | 2014-12-09 | Release date: | 2015-04-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Three-dimensional rational approach to the discovery of potent substituted cyclopropyl urea soluble epoxide hydrolase inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
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8FXB
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![BU of 8fxb by Molmil](/molmil-images/mine/8fxb) | SARS-CoV-2 XBB.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Heavy chain, ... | Authors: | Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | Deposit date: | 2023-01-24 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Neutralization, effector function and immune imprinting of Omicron variants. Nature, 621, 2023
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8FXC
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![BU of 8fxc by Molmil](/molmil-images/mine/8fxc) | SARS-CoV-2 BQ.1.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Heavy chain, ... | Authors: | Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | Deposit date: | 2023-01-24 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Neutralization, effector function and immune imprinting of Omicron variants. Nature, 621, 2023
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3G86
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![BU of 3g86 by Molmil](/molmil-images/mine/3g86) | Hepatitis C virus polymerase NS5B (BK 1-570) with thiazine inhibitor | Descriptor: | N-{3-[6-fluoro-1-(4-fluorobenzyl)-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl]-1,1-dioxido-4H-1,4-benzothiazin-7-yl}methanesulfonamide, NICKEL (II) ION, RNA-directed RNA polymerase | Authors: | Harris, S.F, Ghate, M. | Deposit date: | 2009-02-11 | Release date: | 2009-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Non-nucleoside inhibitors of HCV polymerase NS5B. Part 2: Synthesis and structure-activity relationships of benzothiazine-substituted quinolinediones Bioorg.Med.Chem.Lett., 19, 2009
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8HRX
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![BU of 8hrx by Molmil](/molmil-images/mine/8hrx) | Cryo-EM structure of human NTCP-myr-preS1-YN9048Fab complex | Descriptor: | Fab heavy chain from antibody IgG clone number YN9048, Fab light chain from antibody IgG clone number YN9048, PreS1 protein (Fragment), ... | Authors: | Asami, J, Shimizu, T, Ohto, U. | Deposit date: | 2022-12-16 | Release date: | 2024-01-17 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structural basis of hepatitis B virus receptor binding. Nat.Struct.Mol.Biol., 31, 2024
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8HRY
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![BU of 8hry by Molmil](/molmil-images/mine/8hry) | Cryo-EM structure of human NTCP-myr-preS1-YN9016Fab complex | Descriptor: | Fab heavy chain from antibody IgG clone number YN9016, Fab light chain from antibody IgG clone number YN9016, Large S protein (Fragment), ... | Authors: | Asami, J, Shimizu, T, Ohto, U. | Deposit date: | 2022-12-16 | Release date: | 2024-01-17 | Last modified: | 2024-04-03 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural basis of hepatitis B virus receptor binding. Nat.Struct.Mol.Biol., 31, 2024
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3LG8
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![BU of 3lg8 by Molmil](/molmil-images/mine/3lg8) | Crystal structure of the C-terminal part of subunit E (E101-206) from Methanocaldococcus jannaschii of A1AO ATP synthase | Descriptor: | A-type ATP synthase subunit E | Authors: | Balakrishna, A.M, Manimekalai, M.S.S, Hunke, C, Gayen, S, Jeyakanthan, J, Gruber, G. | Deposit date: | 2010-01-19 | Release date: | 2010-07-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Crystal and solution structure of the C-terminal part of the Methanocaldococcus jannaschii A1AO ATP synthase subunit E revealed by X-ray diffraction and small-angle X-ray scattering J.Bioenerg.Biomembr., 42, 2010
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3H59
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![BU of 3h59 by Molmil](/molmil-images/mine/3h59) | Hepatitis C virus polymerase NS5B with thiazine inhibitor 2 | Descriptor: | N-{3-[(5S)-5-(1,1-dimethylpropyl)-1-(4-fluoro-3-methylbenzyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1,1-dioxido-4H-1,4-benzothiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase | Authors: | Harris, S.F, Ghate, M. | Deposit date: | 2009-04-21 | Release date: | 2009-09-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acids Bioorg.Med.Chem.Lett., 19, 2009
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8XEJ
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![BU of 8xej by Molmil](/molmil-images/mine/8xej) | Cryo-EM structure of human XKR8-basigin complex in lipid nanodisc | Descriptor: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Fab heavy chain, Fab light chain, ... | Authors: | Sakuragi, T.S, Kanai, R.K, Kikkawa, M.K, Toyoshima, C.T, Nagata, S.N. | Deposit date: | 2023-12-12 | Release date: | 2024-02-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase. J.Biol.Chem., 300, 2024
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3WRV
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3WRW
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5IUG
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![BU of 5iug by Molmil](/molmil-images/mine/5iug) | Crystal Structure of Anaplastic Lymphoma Kinase (ALK) in complex with 5a | Descriptor: | ALK tyrosine kinase receptor, N-[3-(4-{[(5-tert-butyl-1,2-oxazol-3-yl)carbamoyl]amino}-3-methylphenyl)-1H-pyrazol-5-yl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide | Authors: | Tu, C.H, Wu, S.Y. | Deposit date: | 2016-03-18 | Release date: | 2016-05-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Pyrazolylamine Derivatives Reveal the Conformational Switching between Type I and Type II Binding Modes of Anaplastic Lymphoma Kinase (ALK). J.Med.Chem., 59, 2016
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