6GYX
Crystal structure of DacA from Staphylococcus aureus in complex with ApCpp
Summary for 6GYX
Entry DOI | 10.2210/pdb6gyx/pdb |
Descriptor | Diadenylate cyclase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MANGANESE (II) ION (3 entities in total) |
Functional Keywords | c-di-amp, diadenylate cyclase, apcpp, transferase |
Biological source | Staphylococcus aureus |
Total number of polymer chains | 2 |
Total formula weight | 39863.48 |
Authors | Tosi, T.,Freemont, P.S.,Grundling, A. (deposition date: 2018-07-02, release date: 2019-01-23, Last modification date: 2024-01-17) |
Primary citation | Tosi, T.,Hoshiga, F.,Millership, C.,Singh, R.,Eldrid, C.,Patin, D.,Mengin-Lecreulx, D.,Thalassinos, K.,Freemont, P.,Grundling, A. Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM. PLoS Pathog., 15:e1007537-e1007537, 2019 Cited by PubMed: 30668586DOI: 10.1371/journal.ppat.1007537 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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