6GYY
Crystal structure of DacA from Staphylococcus aureus, N166C/T172C double mutant
Summary for 6GYY
| Entry DOI | 10.2210/pdb6gyy/pdb |
| Descriptor | Diadenylate cyclase (1 entity in total) |
| Functional Keywords | c-di-amp, diadenylate cyclase, protein engineering, transferase |
| Biological source | Staphylococcus aureus |
| Total number of polymer chains | 2 |
| Total formula weight | 38780.28 |
| Authors | Tosi, T.,Freemont, P.S.,Grundling, A. (deposition date: 2018-07-02, release date: 2019-01-23, Last modification date: 2024-01-17) |
| Primary citation | Tosi, T.,Hoshiga, F.,Millership, C.,Singh, R.,Eldrid, C.,Patin, D.,Mengin-Lecreulx, D.,Thalassinos, K.,Freemont, P.,Grundling, A. Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM. PLoS Pathog., 15:e1007537-e1007537, 2019 Cited by PubMed: 30668586DOI: 10.1371/journal.ppat.1007537 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.77 Å) |
Structure validation
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