7W7U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w7u by Molmil](/molmil-images/mine/7w7u) | The 'Ca2+-unbound' BeF3- of SERCA2b | Descriptor: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Authors: | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | Deposit date: | 2021-12-06 | Release date: | 2022-12-14 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
|
|
7W7W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w7w by Molmil](/molmil-images/mine/7w7w) | E2 Pi of SERCA2b | Descriptor: | MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, TETRAFLUOROALUMINATE ION | Authors: | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | Deposit date: | 2021-12-06 | Release date: | 2022-12-14 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
|
|
7W7T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7w7t by Molmil](/molmil-images/mine/7w7t) | The E1-BeF3- 2Ca2+ of SERCA2b | Descriptor: | BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | Deposit date: | 2021-12-06 | Release date: | 2022-12-14 | Last modified: | 2023-01-11 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
|
|
4OXW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oxw by Molmil](/molmil-images/mine/4oxw) | |
3T94
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t94 by Molmil](/molmil-images/mine/3t94) | |
7E7S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e7s by Molmil](/molmil-images/mine/7e7s) | WT transporter state1 | Descriptor: | CALCIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Authors: | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | Deposit date: | 2021-02-27 | Release date: | 2021-09-08 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM analysis provides new mechanistic insight into ATP binding to Ca 2+ -ATPase SERCA2b. Embo J., 40, 2021
|
|
7D6D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d6d by Molmil](/molmil-images/mine/7d6d) | |
7D6E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d6e by Molmil](/molmil-images/mine/7d6e) | |
7D8K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d8k by Molmil](/molmil-images/mine/7d8k) | Solution structure of the methyl-CpG binding domain of MBD6 from Arabidopsis thaliana | Descriptor: | Methyl-CpG-binding domain-containing protein 6 | Authors: | Mahana, Y, Ohki, I, Walinda, E, Morimoto, D, Sugase, K, Shirakawa, M. | Deposit date: | 2020-10-08 | Release date: | 2021-10-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Insights into Methylated DNA Recognition by the Methyl-CpG Binding Domain of MBD6 from Arabidopsis thaliana . Acs Omega, 7, 2022
|
|
3W1Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3w1z by Molmil](/molmil-images/mine/3w1z) | Heat shock protein 16.0 from Schizosaccharomyces pombe | Descriptor: | Heat shock protein 16 | Authors: | Hanazono, Y, Takeda, K, Akiyama, N, Aikawa, Y, Miki, K. | Deposit date: | 2012-11-26 | Release date: | 2013-03-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Nonequivalence Observed for the 16-Meric Structure of a Small Heat Shock Protein, SpHsp16.0, from Schizosaccharomyces pombe Structure, 21, 2013
|
|
7XH3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xh3 by Molmil](/molmil-images/mine/7xh3) | |
7XFV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xfv by Molmil](/molmil-images/mine/7xfv) | |
3VQL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vql by Molmil](/molmil-images/mine/3vql) | |
3VQK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vqk by Molmil](/molmil-images/mine/3vqk) | |
3VQM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3vqm by Molmil](/molmil-images/mine/3vqm) | |
5WTA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wta by Molmil](/molmil-images/mine/5wta) | Crystal Structure of Staphylococcus aureus SdrE apo form | Descriptor: | Serine-aspartate repeat-containing protein E | Authors: | Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X. | Deposit date: | 2016-12-10 | Release date: | 2017-07-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion Biochem. J., 474, 2017
|
|
5WMG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wmg by Molmil](/molmil-images/mine/5wmg) | N-terminal bromodomain of BRD4 in complex with OTX-015 | Descriptor: | 1,2-ETHANEDIOL, 4-{6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1S)-1-(pyridin-2-yl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl}benzoic acid, Bromodomain-containing protein 4 | Authors: | Zhang, Y. | Deposit date: | 2017-07-28 | Release date: | 2018-08-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | BRD4 Profiling Identifies Critical Chronic Lymphocytic Leukemia Oncogenic Circuits and Reveals Sensitivity to PLX51107, a Novel Structurally Distinct BET Inhibitor. Cancer Discov, 8, 2018
|
|
5LQ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5lq6 by Molmil](/molmil-images/mine/5lq6) | Salmonella effector SpvD - R161 variant | Descriptor: | SODIUM ION, Virulence protein vsdE | Authors: | Zhang, Y, Grabe, G.J, Rolhion, N, Yang, Y, Holden, D.W, Hare, S.A. | Deposit date: | 2016-08-16 | Release date: | 2016-11-02 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | The Salmonella Effector SpvD Is a Cysteine Hydrolase with a Serovar-specific Polymorphism Influencing Catalytic Activity, Suppression of Immune Responses, and Bacterial Virulence. J. Biol. Chem., 291, 2016
|
|
8ZMR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8zmr by Molmil](/molmil-images/mine/8zmr) | Vesamicol-bound VAChT | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7, vesamicol | Authors: | Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H. | Deposit date: | 2024-05-23 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into VAChT neurotransmitter recognition and inhibition. Cell Res., 2024
|
|
8ZMS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8zms by Molmil](/molmil-images/mine/8zms) | Acetylcholine-bound VAChT | Descriptor: | ACETYLCHOLINE, Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7 | Authors: | Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H. | Deposit date: | 2024-05-23 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into VAChT neurotransmitter recognition and inhibition. Cell Res., 2024
|
|
5LS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ls6 by Molmil](/molmil-images/mine/5ls6) | Structure of Human Polycomb Repressive Complex 2 (PRC2) with inhibitor | Descriptor: | 1-[(1~{R})-1-[1-[2,2-bis(fluoranyl)propyl]piperidin-4-yl]ethyl]-~{N}-[(4-methoxy-6-methyl-2-oxidanylidene-3~{H}-pyridin-3-yl)methyl]-2-methyl-indole-3-carboxamide, Histone-lysine N-methyltransferase EZH2,Histone-lysine N-methyltransferase EZH2,Histone-lysine N-methyltransferase EZH2, Jarid2 K116me3, ... | Authors: | Zhang, Y, Justin, N, Chen, S, Wilson, J, Gamblin, S. | Deposit date: | 2016-08-22 | Release date: | 2017-02-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.47 Å) | Cite: | Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas. J. Med. Chem., 59, 2016
|
|
6O1E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o1e by Molmil](/molmil-images/mine/6o1e) | The crystal structure of human MORC3 ATPase-CW in complex with AMPPNP | Descriptor: | MAGNESIUM ION, MORC family CW-type zinc finger protein 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Klein, B.J, Zhang, Y, Kutateladze, T.G. | Deposit date: | 2019-02-19 | Release date: | 2019-03-20 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Mechanism for autoinhibition and activation of the MORC3 ATPase. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
|
|
2ITK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2itk by Molmil](/molmil-images/mine/2itk) | human Pin1 bound to D-PEPTIDE | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, D-Peptide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Noel, J.P, Zhang, Y. | Deposit date: | 2006-10-19 | Release date: | 2007-05-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural basis for high-affinity peptide inhibition of human Pin1. Acs Chem.Biol., 2, 2007
|
|
6CB7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cb7 by Molmil](/molmil-images/mine/6cb7) | |
6CB6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6cb6 by Molmil](/molmil-images/mine/6cb6) | |