3NNH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nnh by Molmil](/molmil-images/mine/3nnh) | Crystal Structure of the CUGBP1 RRM1 with GUUGUUUUGUUU RNA | Descriptor: | CUGBP Elav-like family member 1, RNA (5'-R(*GP*UP*UP*GP*UP*UP*UP*UP*GP*UP*UP*U)-3') | Authors: | Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J. | Deposit date: | 2010-06-23 | Release date: | 2010-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7501 Å) | Cite: | Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1. Structure, 18, 2010
|
|
5IX2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ix2 by Molmil](/molmil-images/mine/5ix2) | Crystal structure of mouse Morc3 ATPase-CW cassette in complex with AMPPNP and unmodified H3 peptide | Descriptor: | MAGNESIUM ION, MORC family CW-type zinc finger protein 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Li, S, Du, J, Patel, D.J. | Deposit date: | 2016-03-23 | Release date: | 2016-08-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
3O37
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o37 by Molmil](/molmil-images/mine/3o37) | |
3O34
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o34 by Molmil](/molmil-images/mine/3o34) | |
6O6Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o6y by Molmil](/molmil-images/mine/6o6y) | Crystal structure of Csm6 in complex with cyclic-tetraadenylates (cA4) by cocrystallization of Csm6 and cA4 | Descriptor: | 2',3'- cyclic AMP, 3'-O-[(R)-{[(2S,3aS,4S,6S,6aS)-6-(6-amino-9H-purin-9-yl)-2-hydroxy-2-oxotetrahydro-2H-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-4-yl]methoxy}(hydroxy)phosphoryl]adenosine, Csm6 | Authors: | Jia, N, Patel, D.J. | Deposit date: | 2019-03-07 | Release date: | 2019-07-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75, 2019
|
|
6O78
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o78 by Molmil](/molmil-images/mine/6o78) | Crystal structure of Csm1-Csm4 cassette in complex with pppApApA | Descriptor: | CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, MANGANESE (II) ION, ... | Authors: | Jia, N, Patel, D.J. | Deposit date: | 2019-03-07 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path. Mol.Cell, 75, 2019
|
|
6UF1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uf1 by Molmil](/molmil-images/mine/6uf1) | Pistol ribozyme transition-state analog vanadate | Descriptor: | MANGANESE (II) ION, RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(GVA)*UP*CP*CP*AP*A)-3'), RNA (50-MER) | Authors: | Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R. | Deposit date: | 2019-09-23 | Release date: | 2019-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
5BS7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bs7 by Molmil](/molmil-images/mine/5bs7) | Structure of histone H3/H4 in complex with Spt2 | Descriptor: | Histone H3.2, Histone H4, Protein SPT2 homolog, ... | Authors: | Chen, S, Patel, D.J. | Deposit date: | 2015-06-01 | Release date: | 2015-07-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2. Genes Dev., 29, 2015
|
|
6O6V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o6v by Molmil](/molmil-images/mine/6o6v) | |
6O73
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o73 by Molmil](/molmil-images/mine/6o73) | Crystal structure of apo Csm1-Csm4 cassette | Descriptor: | Csm1, Csm4, NICKEL (II) ION | Authors: | Jia, N, Patel, D.J. | Deposit date: | 2019-03-07 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path. Mol.Cell, 75, 2019
|
|
5IW5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iw5 by Molmil](/molmil-images/mine/5iw5) | |
6O70
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o70 by Molmil](/molmil-images/mine/6o70) | Crystal structure of Csm6 H132A mutant in complex with cA4 by cocrystallization of cA4 and Csm6 H132A mutant | Descriptor: | 2',3'- cyclic AMP, 3'-O-[(R)-{[(2S,3aS,4S,6S,6aS)-6-(6-amino-9H-purin-9-yl)-2-hydroxy-2-oxotetrahydro-2H-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-4-yl]methoxy}(hydroxy)phosphoryl]adenosine, Csm6 | Authors: | Jia, N, Patel, D.J. | Deposit date: | 2019-03-07 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75, 2019
|
|
6O47
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o47 by Molmil](/molmil-images/mine/6o47) | human cGAS core domain (K427E/K428E) bound with RU-521 | Descriptor: | (3~{S})-3-[1-[4,5-bis(chloranyl)-1~{H}-benzimidazol-2-yl]-3-methyl-5-oxidanyl-pyrazol-4-yl]-3~{H}-2-benzofuran-1-one, 2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-[(1R)-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-1,2-dihydro-3H-pyrazol-3-one, CITRIC ACID, ... | Authors: | Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J. | Deposit date: | 2019-02-28 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.196 Å) | Cite: | Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6O6Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o6z by Molmil](/molmil-images/mine/6o6z) | Crystal structure of Csm6 H381A in complex with cA4 by cocrystallization of cA4 and Csm6 | Descriptor: | 3'-O-[(R)-{[(2S,3aS,4S,6S,6aS)-6-(6-amino-9H-purin-9-yl)-2-hydroxy-2-oxotetrahydro-2H-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-4-yl]methoxy}(hydroxy)phosphoryl]adenosine, Csm6 | Authors: | Jia, N, Patel, D.J. | Deposit date: | 2019-03-07 | Release date: | 2019-07-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75, 2019
|
|
6O79
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o79 by Molmil](/molmil-images/mine/6o79) | Crystal structure of Csm1-Csm4 cassette in complex with cA3 | Descriptor: | CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, cyclic RNA cA3 | Authors: | Jia, N, Patel, D.J. | Deposit date: | 2019-03-07 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path. Mol.Cell, 75, 2019
|
|
2A5R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2a5r by Molmil](/molmil-images/mine/2a5r) | Complex of tetra-(4-n-methylpyridyl) porphin with monomeric parallel-stranded DNA tetraplex, snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, C-MYC promoter, NMR, 6 struct. | Descriptor: | (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3' | Authors: | Phan, A.T, Kuryavyi, V.V, Gaw, H.Y, Patel, D.J. | Deposit date: | 2005-06-30 | Release date: | 2005-07-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter. Nat.Chem.Biol., 1, 2005
|
|
6O7E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o7e by Molmil](/molmil-images/mine/6o7e) | |
2A5P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2a5p by Molmil](/molmil-images/mine/2a5p) | Monomeric parallel-stranded DNA tetraplex with snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, NMR, 8 struct. | Descriptor: | 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3' | Authors: | Phan, A.T, Kuryavyi, V.V, Gaw, H.Y, Patel, D.J. | Deposit date: | 2005-06-30 | Release date: | 2005-07-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter. Nat.Chem.Biol., 1, 2005
|
|
6O7I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o7i by Molmil](/molmil-images/mine/6o7i) | |
3OWZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3owz by Molmil](/molmil-images/mine/3owz) | Crystal structure of glycine riboswitch, soaked in Iridium | Descriptor: | Domain II of glycine riboswitch, GLYCINE, IRIDIUM HEXAMMINE ION, ... | Authors: | Huang, L, Serganov, A, Patel, D.J. | Deposit date: | 2010-09-20 | Release date: | 2010-12-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.949 Å) | Cite: | Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch. Mol.Cell, 40, 2010
|
|
6UFJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ufj by Molmil](/molmil-images/mine/6ufj) | Pistol ribozyme product crystal structure | Descriptor: | MAGNESIUM ION, RNA (5'-R(*UP*CP*CP*AP*G)-3'), RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(23G))-3'), ... | Authors: | Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R. | Deposit date: | 2019-09-24 | Release date: | 2019-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.645 Å) | Cite: | Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
6O6X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o6x by Molmil](/molmil-images/mine/6o6x) | |
3OXB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oxb by Molmil](/molmil-images/mine/3oxb) | |
3OXM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oxm by Molmil](/molmil-images/mine/3oxm) | crystal structure of glycine riboswitch, Tl-Acetate soaked | Descriptor: | GLYCINE, MAGNESIUM ION, THALLIUM (I) ION, ... | Authors: | Huang, L, Serganov, A, Patel, D.J. | Deposit date: | 2010-09-21 | Release date: | 2010-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural insights into ligand recognition by a sensing domain of the cooperative glycine riboswitch. Mol.Cell, 40, 2010
|
|
6UEY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uey by Molmil](/molmil-images/mine/6uey) | Pistol ribozyme transition-state analog vanadate | Descriptor: | MAGNESIUM ION, RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(GVA)*UP*CP*CP*AP*A)-3'), RNA (50-MER) | Authors: | Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R. | Deposit date: | 2019-09-23 | Release date: | 2019-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme. Angew.Chem.Int.Ed.Engl., 59, 2020
|
|