3RQ8
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![BU of 3rq8 by Molmil](/molmil-images/mine/3rq8) | Crystal Structure of ADP/ATP-dependent NAD(P)H-hydrate dehydratase from Bacillus subtilis soaked with P1,P5-Di(adenosine-5') pentaphosphate | Descriptor: | ADP/ATP-dependent NAD(P)H-hydrate dehydratase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION | Authors: | Shumilin, I.A, Cymborowski, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-04-27 | Release date: | 2011-07-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Identification of unknown protein function using metabolite cocktail screening. Structure, 20, 2012
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3RY3
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![BU of 3ry3 by Molmil](/molmil-images/mine/3ry3) | Putative solute-binding protein from Yersinia pestis. | Descriptor: | ACETATE ION, Putative solute-binding protein | Authors: | Osipiuk, J, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-05-10 | Release date: | 2011-05-18 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Putative solute-binding protein from Yersinia pestis. To be Published
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3RXY
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![BU of 3rxy by Molmil](/molmil-images/mine/3rxy) | Crystal structure of NIF3 superfamily protein from Sphaerobacter thermophilus | Descriptor: | ACETATE ION, CHLORIDE ION, FORMIC ACID, ... | Authors: | Michalska, K, Tesar, C, Clancy, S, Otwinowski, Z, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-05-10 | Release date: | 2011-06-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of NIF3 superfamily protein from Sphaerobacter thermophilus To be Published
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3RXZ
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![BU of 3rxz by Molmil](/molmil-images/mine/3rxz) | Crystal structure of putative polysaccharide deacetylase from Mycobacterium smegmatis | Descriptor: | CHLORIDE ION, Polysaccharide deacetylase, ZINC ION | Authors: | Michalska, K, Tesar, C, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-05-10 | Release date: | 2011-06-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal structure of putative polysaccharide deacetylase from Mycobacterium smegmatis To be Published
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3S19
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![BU of 3s19 by Molmil](/molmil-images/mine/3s19) | Crystal Structure of the R262L mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0 | Descriptor: | 7-DEAZA-7-AMINOMETHYL-GUANINE, GLYCEROL, NADPH-dependent 7-cyano-7-deazaguanine reductase | Authors: | Kim, Y, Zhou, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-05-14 | Release date: | 2011-06-29 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.5009 Å) | Cite: | Crystal Structure of the R262L mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0 To be Published
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3RZP
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![BU of 3rzp by Molmil](/molmil-images/mine/3rzp) | Crystal Structure of the C194A mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ1 | Descriptor: | 7-DEAZA-7-AMINOMETHYL-GUANINE, GLYCEROL, NADPH-dependent 7-cyano-7-deazaguanine reductase | Authors: | Kim, Y, Zhou, M, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-05-12 | Release date: | 2011-06-29 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the C194A mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ1 To be Published
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3WRP
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7O62
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![BU of 7o62 by Molmil](/molmil-images/mine/7o62) | |
6PU9
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![BU of 6pu9 by Molmil](/molmil-images/mine/6pu9) | Crystal Structure of the Type B Chloramphenicol O-Acetyltransferase from Vibrio vulnificus | Descriptor: | 1,2-ETHANEDIOL, Acetyltransferase, CHLORIDE ION | Authors: | Kim, Y, Maltseva, N, Mulligan, R, Grimshaw, S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-07-17 | Release date: | 2019-08-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and functional characterization of three Type B and C chloramphenicol acetyltransferases from Vibrio species. Protein Sci., 29, 2020
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6PUA
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![BU of 6pua by Molmil](/molmil-images/mine/6pua) | The 2.0 A Crystal Structure of the Type B Chloramphenicol Acetyltransferase from Vibrio cholerae | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ... | Authors: | Kim, Y, Maltseva, N, Stam, J, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-07-18 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and functional characterization of three Type B and C chloramphenicol acetyltransferases from Vibrio species. Protein Sci., 29, 2020
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1JL4
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![BU of 1jl4 by Molmil](/molmil-images/mine/1jl4) | CRYSTAL STRUCTURE OF THE HUMAN CD4 N-TERMINAL TWO DOMAIN FRAGMENT COMPLEXED TO A CLASS II MHC MOLECULE | Descriptor: | H-2 CLASS II HISTOCOMPATIBILITY ANTIGEN, A-K ALPHA CHAIN, A-K BETA CHAIN, ... | Authors: | Wang, J.-H, Meijers, R, Reinherz, E.L. | Deposit date: | 2001-07-15 | Release date: | 2001-09-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (4.3 Å) | Cite: | Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule. Proc.Natl.Acad.Sci.USA, 98, 2001
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6CQI
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![BU of 6cqi by Molmil](/molmil-images/mine/6cqi) | 2.42A Crystal structure of Mycobacterium tuberculosis Topoisomerase I in complex with an oligonucleotide MTS2-11 | Descriptor: | ACETATE ION, DNA (5'-D(P*TP*TP*CP*CP*GP*CP*TP*TP*GP*A)-3'), DNA topoisomerase 1, ... | Authors: | Cao, N, Thirunavukkarasu, A, Tan, K, Tse-Dinh, Y.-C. | Deposit date: | 2018-03-15 | Release date: | 2018-05-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site. Nucleic Acids Res., 46, 2018
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6CQ2
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![BU of 6cq2 by Molmil](/molmil-images/mine/6cq2) | Crystal structure of Mycobacterium tuberculosis Topoisomerase I in complex with oligonucleotide MTS2-12 and Magnesium | Descriptor: | DNA (5'-D(P*TP*TP*CP*CP*GP*CP*TP*TP*GP*A)-3'), DNA topoisomerase 1, MAGNESIUM ION, ... | Authors: | Cao, N, Thirunavukkaraus, A, Tan, K, Tse-Dinh, Y.-C. | Deposit date: | 2018-03-14 | Release date: | 2018-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site. Nucleic Acids Res., 46, 2018
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4W8I
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![BU of 4w8i by Molmil](/molmil-images/mine/4w8i) | Crystal structure of LpSPL/Lpp2128, Legionella pneumophila sphingosine-1 phosphate lyase | Descriptor: | Probable sphingosine-1-phosphate lyase | Authors: | Stogios, P.J, Daniels, C, Skarina, T, Cuff, M, Di Leo, R, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-08-24 | Release date: | 2014-11-05 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy. Proc.Natl.Acad.Sci.USA, 113, 2016
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4W97
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![BU of 4w97 by Molmil](/molmil-images/mine/4w97) | Structure of ketosteroid transcriptional regulator KstR2 of Mycobacterium tuberculosis | Descriptor: | CHLORIDE ION, HTH-type transcriptional repressor KstR2, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] 3-[(3aS,4S,7aS)-7a-methyl-1,5-bis(oxidanylidene)-2,3,3a,4,6,7-hexahydroinden-4-yl]propanethioate | Authors: | Stogios, P.J, Evdokimova, E, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2014-08-27 | Release date: | 2014-11-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and Functional Characterization of a Ketosteroid Transcriptional Regulator of Mycobacterium tuberculosis. J.Biol.Chem., 290, 2015
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6D00
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![BU of 6d00 by Molmil](/molmil-images/mine/6d00) | Calcarisporiella thermophila Hsp104 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Calcarisporiella thermophila Hsp104 | Authors: | Zhang, K, Pintilie, G. | Deposit date: | 2018-04-09 | Release date: | 2019-04-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events. Structure, 27, 2019
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5D5H
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![BU of 5d5h by Molmil](/molmil-images/mine/5d5h) | Crystal structure of Mycobacterium tuberculosis Topoisomerase I | Descriptor: | ACETATE ION, DNA topoisomerase 1, GLYCEROL, ... | Authors: | Tan, K, Cheng, B, Tse-Dinh, Y.C. | Deposit date: | 2015-08-10 | Release date: | 2015-12-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | Insights from the Structure of Mycobacterium tuberculosis Topoisomerase I with a Novel Protein Fold. J.Mol.Biol., 428, 2016
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6HCD
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![BU of 6hcd by Molmil](/molmil-images/mine/6hcd) | Structure of universal stress protein from Archaeoglobus fulgidus | Descriptor: | ACETATE ION, CHLORIDE ION, UNIVERSAL STRESS PROTEIN, ... | Authors: | Shumilin, I.A, Loch, J.I, Cymborowski, M, Xu, X, Edwards, A, Di Leo, R, Shabalin, I.G, Joachimiak, A, Savchenko, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2018-08-14 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and functional insight into the universal stress protein family. Evol Appl, 6, 2013
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6W1I
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![BU of 6w1i by Molmil](/molmil-images/mine/6w1i) | Re-interpretation of ppGpp (G4P) electron density in the deposited crystal structure of Xanthine phosphoribosyltransferase (XPRT) (1Y0B). | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, SODIUM ION, Xanthine phosphoribosyltransferase | Authors: | Satyshur, K.A, Anderson, B.W, Keck, J.L, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2020-03-04 | Release date: | 2020-07-29 | Last modified: | 2021-04-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular Mechanism of Regulation of the Purine Salvage Enzyme XPRT by the Alarmones pppGpp, ppGpp, and pGpp. J.Mol.Biol., 432, 2020
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5CXD
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![BU of 5cxd by Molmil](/molmil-images/mine/5cxd) | 1.75 Angstrom resolution crystal structure of the apo-form acyl-carrier-protein synthase (AcpS) (acpS; purification tag off) from Staphylococcus aureus subsp. aureus COL in the I4 space group | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Holo-[acyl-carrier-protein] synthase, ... | Authors: | Halavaty, A.S, Minasov, G, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2015-07-28 | Release date: | 2015-08-05 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | 1.75 Angstrom resolution crystal structure of the apo-form acyl-carrier-protein synthase (AcpS) (acpS; purification tag off) from Staphylococcus aureus subsp. aureus COL in the I4 space group To Be Published
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2J8T
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![BU of 2j8t by Molmil](/molmil-images/mine/2j8t) | Human aldose reductase in complex with NADP and citrate at 0.82 angstrom | Descriptor: | ALDO-KETO REDUCTASE FAMILY 1, MEMBER B1, CITRATE ANION, ... | Authors: | Biadene, M, Hazemann, I, Cousido, A, Ginell, S, Sheldrick, G.M, Podjarny, A, Schneider, T.R. | Deposit date: | 2006-10-27 | Release date: | 2007-05-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (0.82 Å) | Cite: | The Atomic Resolution Structure of Human Aldose Reductase Reveals that Rearrangement of a Bound Ligand Allows the Opening of the Safety-Belt Loop. Acta Crystallogr.,Sect.D, 63, 2007
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6SDA
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![BU of 6sda by Molmil](/molmil-images/mine/6sda) | Bd2924 C10 acyl-coenzymeA bound form | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Probable acyl-CoA dehydrogenase, decanoyl-CoA | Authors: | Lovering, A.L, Harding, C.J. | Deposit date: | 2019-07-26 | Release date: | 2019-09-11 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Target highlights in CASP13: Experimental target structures through the eyes of their authors. Proteins, 87, 2019
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6SD8
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![BU of 6sd8 by Molmil](/molmil-images/mine/6sd8) | Bd2924 apo-form | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Probable acyl-CoA dehydrogenase | Authors: | Lovering, A.L, Harding, C.J. | Deposit date: | 2019-07-26 | Release date: | 2019-09-11 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Target highlights in CASP13: Experimental target structures through the eyes of their authors. Proteins, 87, 2019
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8TUK
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![BU of 8tuk by Molmil](/molmil-images/mine/8tuk) | Alvinella ASCC1 KH and Phosphodiesterase/Ligase Domain | Descriptor: | 1,2-ETHANEDIOL, Activating signal cointegrator 1 complex subunit 1, IMIDAZOLE | Authors: | Tsutakawa, S.E, Tainer, J.A, Arvai, A.S, Chinnam, N.B. | Deposit date: | 2023-08-16 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase. J.Biol.Chem., 300, 2024
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8TLY
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![BU of 8tly by Molmil](/molmil-images/mine/8tly) | |