4Q2W
 
 | | Crystal Structure of pneumococcal peptidoglycan hydrolase LytB | | Descriptor: | GLYCEROL, Putative endo-beta-N-acetylglucosaminidase | | Authors: | Bai, X.H, Chen, H.J, Jiang, Y.L, Wen, Z, Cheng, W, Li, Q, Zhang, J.R, Chen, Y, Zhou, C.Z. | | Deposit date: | 2014-04-10 | | Release date: | 2014-07-16 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of pneumococcal peptidoglycan hydrolase LytB reveals insights into the bacterial cell wall remodeling and pathogenesis.
J.Biol.Chem., 289, 2014
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6M52
 | | Human apo ferritin frozen on TEM grid with amorphous carbon supporting film | | Descriptor: | FE (II) ION, Ferritin heavy chain | | Authors: | Huang, X, Zhang, L, Wen, Z, Chen, H, Li, S, Ji, G, Yin, C, Sun, F. | | Deposit date: | 2020-03-09 | | Release date: | 2020-05-13 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation.
Prog.Biophys.Mol.Biol., 156, 2020
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6M54
 | | Human apo ferritin frozen on TEM grid with Amorphous nickel titanium alloy supporting film | | Descriptor: | FE (II) ION, Ferritin heavy chain | | Authors: | Huang, X, Zhang, L, Wen, Z, Chen, H, Li, S, Ji, G, Yin, C, Sun, F. | | Deposit date: | 2020-03-09 | | Release date: | 2020-05-13 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation.
Prog.Biophys.Mol.Biol., 156, 2020
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7XMR
 | | CryoEM structure of the somatostatin receptor 2 (SSTR2) in complex with Gi1 and its endogeneous peptide ligand SST-14 | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | | Deposit date: | 2022-04-26 | | Release date: | 2022-08-03 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors.
Cell Res., 32, 2022
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7XMS
 | | CryoEM structure of somatostatin receptor 4 (SSTR4) in complex with Gi1 and its endogeneous ligand SST-14 | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | Authors: | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | | Deposit date: | 2022-04-26 | | Release date: | 2022-08-03 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors.
Cell Res., 32, 2022
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7XMT
 | | CryoEM structure of somatostatin receptor 4 (SSTR4) with Gi1 and J-2156 | | Descriptor: | (2~{S})-2-[[(2~{S})-4-azanyl-2-[(4-methylnaphthalen-1-yl)sulfonylamino]butanoyl]amino]-3-phenyl-propanimidic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | | Deposit date: | 2022-04-26 | | Release date: | 2022-08-03 | | Last modified: | 2022-08-17 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors.
Cell Res., 32, 2022
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7Y04
 | | Hsp90-AhR-p23 complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Aryl hydrocarbon receptor, BERYLLIUM TRIFLUORIDE ION, ... | | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | | Deposit date: | 2022-06-03 | | Release date: | 2023-01-04 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM structure of the cytosolic AhR complex.
Structure, 31, 2023
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8H77
 | | Hsp90-AhR-p23-XAP2 complex | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, AH receptor-interacting protein, Aryl hydrocarbon receptor, ... | | Authors: | Wen, Z.L, Zhai, Y.J, Zhu, Y, Sun, F. | | Deposit date: | 2022-10-19 | | Release date: | 2023-01-04 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structure of the cytosolic AhR complex.
Structure, 31, 2023
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7VA8
 | | Crystal structure of MiCGT | | Descriptor: | UDP-glycosyltransferase 13, URIDINE-5'-DIPHOSPHATE-GLUCOSE | | Authors: | Zhong, L, Zhang, Z.M. | | Deposit date: | 2021-08-27 | | Release date: | 2022-07-06 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.85003233 Å) | | Cite: | Directed Evolution of a Plant Glycosyltransferase for Chemo- and Regioselective Glycosylation of Pharmaceutically Significant Flavonoids
Acs Catalysis, 11, 2021
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7VAA
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3G5B
 | | The structure of UNC5b cytoplasmic domain | | Descriptor: | Netrin receptor UNC5B, PHOSPHATE ION | | Authors: | Wang, R, Wei, Z, Zhang, M. | | Deposit date: | 2009-02-04 | | Release date: | 2009-04-07 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor
Mol.Cell, 33, 2009
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6OUS
 | | Structure of fusion glycoprotein from human respiratory syncytial virus | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, ... | | Authors: | Su, H.P. | | Deposit date: | 2019-05-05 | | Release date: | 2019-10-30 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein.
Nat Commun, 10, 2019
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2LW9
 | | NMR solution structure of Myo10 anti-CC | | Descriptor: | Unconventionnal myosin-X | | Authors: | Ye, F, Lu, Q, Zhang, M. | | Deposit date: | 2012-07-25 | | Release date: | 2012-09-26 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Antiparallel coiled-coil-mediated dimerization of myosin X
Proc.Natl.Acad.Sci.USA, 109, 2012
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8JHF
 | | Native SUV420H1 bound to 167-bp nucleosome | | Descriptor: | DNA (160-MER), Histone H2A.Z, Histone H2B type 1-K, ... | | Authors: | Lin, F, Li, W. | | Deposit date: | 2023-05-23 | | Release date: | 2023-11-15 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.68 Å) | | Cite: | Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase.
Cell Discov, 9, 2023
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8JHG
 | | Native SUV420H1 bound to 167-bp nucleosome | | Descriptor: | DNA (160-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | Authors: | Lin, F, Li, W. | | Deposit date: | 2023-05-23 | | Release date: | 2023-11-22 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.58 Å) | | Cite: | Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase.
Cell Discov, 9, 2023
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7YRD
 | | histone methyltransferase | | Descriptor: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | | Authors: | Li, H, Wang, W.Y. | | Deposit date: | 2022-08-09 | | Release date: | 2023-08-16 | | Last modified: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1.
Mol.Cell, 83, 2023
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7YRG
 | | histone methyltransferase | | Descriptor: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | | Authors: | Li, H, Wang, W.Y. | | Deposit date: | 2022-08-09 | | Release date: | 2023-12-13 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1.
Mol.Cell, 83, 2023
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6IRR
 | | Solution structure of DISC1/ATF4 complex | | Descriptor: | Disrupted in schizophrenia 1 homolog,Cyclic AMP-dependent transcription factor ATF-4 | | Authors: | Ye, F, Yu, C, Zhang, M. | | Deposit date: | 2018-11-14 | | Release date: | 2019-09-25 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders.
Mol. Psychiatry, 2019
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8T9Z
 | | Structural of M8C10 Fab in complex human metapneumovirus fusion protein | | Descriptor: | Fusion glycoprotein F0, M8C10 Fab Heavy Chain, M8C10 Fab Light Chain | | Authors: | Su, H.P, Eddins, M.J, Shipman, J.M, Kostas, J, Reid, J.C. | | Deposit date: | 2023-06-26 | | Release date: | 2023-11-22 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.995 Å) | | Cite: | Structural characterization of M8C10, a neutralizing antibody targeting a highly conserved prefusion-specific epitope on the metapneumovirus fusion trimerization interface.
J.Virol., 97, 2023
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4EHG
 | | B-Raf Kinase Domain in Complex with an Aminopyridimine-based Inhibitor | | Descriptor: | N-{2,4-difluoro-3-[({6-[(2-hydroxyethyl)amino]pyrimidin-4-yl}carbamoyl)amino]phenyl}propane-1-sulfonamide, Serine/threonine-protein kinase B-raf | | Authors: | Voegtli, W.C. | | Deposit date: | 2012-04-02 | | Release date: | 2013-04-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Potent and selective aminopyrimidine-based B-raf inhibitors with favorable physicochemical and pharmacokinetic properties.
J.Med.Chem., 55, 2012
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4EHE
 | | B-Raf Kinase Domain in Complex with an Aminothienopyrimidine-based Inhibitor | | Descriptor: | 4-amino-N-{2,6-difluoro-3-[(propylsulfonyl)amino]phenyl}thieno[3,2-d]pyrimidine-7-carboxamide, Serine/threonine-protein kinase B-raf | | Authors: | Voegtli, W.C. | | Deposit date: | 2012-04-02 | | Release date: | 2013-04-24 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Potent and selective aminopyrimidine-based B-raf inhibitors with favorable physicochemical and pharmacokinetic properties.
J.Med.Chem., 55, 2012
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2N9B
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4MBJ
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8GXR
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6IX4
 | | Structure of an epoxide hydrolase from Aspergillus usamii E001 (AuEH2) at 1.51 Angstroms resolution | | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Hu, D, Hu, B.C, Hou, X.D, Wu, L, Rao, Y.J, Wu, M.C. | | Deposit date: | 2018-12-09 | | Release date: | 2019-12-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.511 Å) | | Cite: | Nearly perfect kinetic resolution of racemic o-nitrostyrene oxide by AuEH2, a microsomal epoxide hydrolase from Aspergillus usamii, with high enantio- and regio-selectivity.
Int.J.Biol.Macromol., 169, 2021
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