8T9Z
Structural of M8C10 Fab in complex human metapneumovirus fusion protein
Summary for 8T9Z
Entry DOI | 10.2210/pdb8t9z/pdb |
Descriptor | Fusion glycoprotein F0, M8C10 Fab Heavy Chain, M8C10 Fab Light Chain, ... (4 entities in total) |
Functional Keywords | neutralizing antibody, respiratory, metapneumovirus, fusion, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human metapneumovirus More |
Total number of polymer chains | 3 |
Total formula weight | 100125.63 |
Authors | Su, H.P.,Eddins, M.J.,Shipman, J.M.,Kostas, J.,Reid, J.C. (deposition date: 2023-06-26, release date: 2023-11-22, Last modification date: 2023-12-27) |
Primary citation | Xiao, X.,Wen, Z.,Chen, Q.,Shipman, J.M.,Kostas, J.,Reid, J.C.,Warren, C.,Tang, A.,Luo, B.,O'Donnell, G.,Fridman, A.,Chen, Z.,Vora, K.A.,Zhang, L.,Su, H.-P.,Eddins, M.J. Structural characterization of M8C10, a neutralizing antibody targeting a highly conserved prefusion-specific epitope on the metapneumovirus fusion trimerization interface. J.Virol., 97:e0105223-e0105223, 2023 Cited by PubMed: 38032197DOI: 10.1128/jvi.01052-23 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.995 Å) |
Structure validation
Download full validation report