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5JMC
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BU of 5jmc by Molmil
Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C
Descriptor: Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C
Authors:Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
Deposit date:2016-04-28
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
5JLV
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BU of 5jlv by Molmil
Receptor binding domain of Botulinum neurotoxin A in complex with human glycosylated SV2C
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R.
Deposit date:2016-04-27
Release date:2016-06-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
Nat.Struct.Mol.Biol., 23, 2016
3R4S
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BU of 3r4s by Molmil
Cell entry of botulinum neurotoxin type C is dependent upon interaction with two ganglioside molecules
Descriptor: Botulinum neurotoxin type C1, N-acetyl-alpha-neuraminic acid, N-acetyl-beta-neuraminic acid
Authors:Strotmeier, J, Gu, S, Jutzi, S, Mahrhold, S, Zhou, J, Pich, A, Bigalke, H, Rummel, A, Jin, R, Binz, T.
Deposit date:2011-03-17
Release date:2011-06-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
3R4U
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BU of 3r4u by Molmil
Cell entry of botulinum neurotoxin type C is dependent upon interaction with two ganglioside molecules
Descriptor: Botulinum neurotoxin type C1
Authors:Strotmeier, J, Gu, S, Jutzi, S, Mahrhold, S, Zhou, J, Pich, A, Bigalke, H, Rummel, A, Jin, R, Binz, T.
Deposit date:2011-03-17
Release date:2011-06-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
3OBR
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BU of 3obr by Molmil
Crystal structure of Botulinum neurotoxin serotype D binding domain
Descriptor: Botulinum neurotoxin type D, GLYCEROL
Authors:Zong, Y, Lee, K.K, Jin, R.
Deposit date:2010-08-09
Release date:2010-09-08
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
Biochem.J., 431, 2010
5BP5
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BU of 5bp5 by Molmil
Crystal structure of HA17-HA33-IPT
Descriptor: 1-methylethyl 1-thio-beta-D-galactopyranoside, HA-17, HA-33
Authors:Lee, K, Lam, K, Jin, R.
Deposit date:2015-05-27
Release date:2015-09-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics.
Toxicon, 107, 2015
5BQU
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BU of 5bqu by Molmil
Crystal structure of HA17-HA33-Lactulose
Descriptor: HA-17, HA-33, beta-D-galactopyranose-(1-4)-beta-D-fructofuranose
Authors:Lee, K, Lam, K, Jin, R.
Deposit date:2015-05-29
Release date:2015-10-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Inhibiting oral intoxication of botulinum neurotoxin A complex by carbohydrate receptor mimics.
Toxicon, 107, 2015
3OBT
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BU of 3obt by Molmil
Crystal structure of Botulinum neurotoxin serotype D ligand binding domain in complex with N-Acetylneuraminic acid
Descriptor: Botulinum neurotoxin type D, GLYCEROL, N-acetyl-beta-neuraminic acid
Authors:Lee, K.K, Zong, Y, Jin, R.
Deposit date:2010-08-09
Release date:2010-09-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
Biochem.J., 431, 2010

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數據於2024-10-30公開中

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