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5Y3Q
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BU of 5y3q by Molmil
Crystal structure of SARS coronavirus papain-like protease conjugated with beta-mercaptoethanol
Descriptor: BETA-MERCAPTOETHANOL, GLYCEROL, Replicase polyprotein 1a, ...
Authors:Lin, M.H, Chou, C.Y.
Deposit date:2017-07-29
Release date:2018-01-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes
Antiviral Res., 150, 2017
5Y3E
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BU of 5y3e by Molmil
Crystal structure of SARS coronavirus papain-like protease in complex with glycerol
Descriptor: GLYCEROL, Replicase polyprotein 1a, SODIUM ION, ...
Authors:Lin, M.H, Chou, C.Y.
Deposit date:2017-07-28
Release date:2018-01-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes
Antiviral Res., 150, 2017
7C33
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BU of 7c33 by Molmil
Macro domain of SARS-CoV-2 in complex with ADP-ribose
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3
Authors:Lin, M.H, Hsu, C.H.
Deposit date:2020-05-11
Release date:2020-11-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.83 Å)
Cite:Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain.
Acs Infect Dis., 6, 2020
7CZ4
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BU of 7cz4 by Molmil
Structure of SARS-CoV-2 macro domain in complex with ADP-ribose
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3
Authors:Lin, M.H, Hsu, C.H.
Deposit date:2020-09-07
Release date:2020-11-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain.
Acs Infect Dis., 6, 2020
7C4H
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BU of 7c4h by Molmil
Crystal structure of BCP1 from Saccharomyces Cerevisiae
Descriptor: CALCIUM ION, Protein BCP1
Authors:Chang, W.C, Lin, M.H, Hsu, C.H.
Deposit date:2020-05-17
Release date:2020-12-09
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:The crystal structure of protein-transporting chaperone BCP1 from Saccharomyces cerevisiae.
J.Struct.Biol., 212, 2020
7COT
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BU of 7cot by Molmil
Structure of post fusion core of SARS-CoV-2 S2 subunit
Descriptor: Spike glycoprotein
Authors:Lin, M.H, Tan, K.P, Hsu, C.H.
Deposit date:2020-08-05
Release date:2021-08-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structure of post fusion core of SARS-CoV-2 S2 subunit
To Be Published
5YB9
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BU of 5yb9 by Molmil
Crystal structure of a dimeric cyclophilin A from T.vaginalis
Descriptor: Peptidyl-prolyl cis-trans isomerase
Authors:Cho, C.C, Lin, M.H, Chou, C.C, Martin, T, Chen, C, Hsu, C.H.
Deposit date:2017-09-04
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.276 Å)
Cite:Structural basis of interaction between dimeric cyclophilin 1 and Myb1 transcription factor in Trichomonas vaginalis
Sci Rep, 8, 2018
5YBA
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BU of 5yba by Molmil
Dimeric Cyclophilin from T.vaginalis in complex with Myb1 peptide
Descriptor: Myb1 peptide, Peptidyl-prolyl cis-trans isomerase
Authors:Cho, C.C, Lin, M.H, Martin, T, Chou, C.C, Chen, C, Hsu, C.H.
Deposit date:2017-09-04
Release date:2018-07-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.062 Å)
Cite:Structural basis of interaction between dimeric cyclophilin 1 and Myb1 transcription factor in Trichomonas vaginalis
Sci Rep, 8, 2018
7SN8
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BU of 7sn8 by Molmil
Cryo-EM structure of Drosophila Integrator cleavage module (IntS4-IntS9-IntS11) in complex with IP6
Descriptor: INOSITOL HEXAKISPHOSPHATE, Integrator complex subunit 11, Integrator complex subunit 4, ...
Authors:Lin, M, Tong, L.
Deposit date:2021-10-27
Release date:2022-10-12
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Inositol hexakisphosphate is required for Integrator function.
Nat Commun, 13, 2022
8I26
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BU of 8i26 by Molmil
NMR structure of Toxoplasma gondii PDCD5 (cis form)
Descriptor: Programmed cell death 5 protein
Authors:Lin, M.H, Hsu, C.H.
Deposit date:2023-01-14
Release date:2024-01-17
Last modified:2024-06-12
Method:SOLUTION NMR
Cite:Proline Isomerization and Molten Globular Property of TgPDCD5 Secreted from Toxoplasma gondii Confers Its Regulation of Heparin Sulfate Binding.
Jacs Au, 4, 2024
8I25
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BU of 8i25 by Molmil
NMR structure of Toxoplasma gondii PDCD5 (trans form)
Descriptor: Programmed cell death 5 protein
Authors:Lin, M.H, Hsu, C.H.
Deposit date:2023-01-14
Release date:2024-01-17
Last modified:2024-06-12
Method:SOLUTION NMR
Cite:Proline Isomerization and Molten Globular Property of TgPDCD5 Secreted from Toxoplasma gondii Confers Its Regulation of Heparin Sulfate Binding.
Jacs Au, 4, 2024
8UIC
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BU of 8uic by Molmil
Structure of the Drosophila IntS11-CG7044(dBRAT1) complex
Descriptor: FI02071p, Integrator complex subunit 11, ZINC ION
Authors:Lin, M, Tong, L.
Deposit date:2023-10-10
Release date:2024-08-21
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function.
Mol.Cell, 84, 2024
8UIB
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BU of 8uib by Molmil
Structure of the human INTS9-INTS11-BRAT1 complex
Descriptor: BRCA1-associated ATM activator 1, Integrator complex subunit 11, Integrator complex subunit 9, ...
Authors:Lin, M, Tong, L.
Deposit date:2023-10-10
Release date:2024-08-21
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function.
Mol.Cell, 84, 2024
3O50
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BU of 3o50 by Molmil
Crystal structure of benzamide 9 bound to AuroraA
Descriptor: N-{3-methyl-4-[(3-pyrimidin-4-ylpyridin-2-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide, cDNA FLJ58295, highly similar to Serine/threonine-protein kinase 6
Authors:Huang, X.
Deposit date:2010-07-27
Release date:2010-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of a potent, selective, and orally bioavailable pyridinyl-pyrimidine phthalazine aurora kinase inhibitor.
J.Med.Chem., 53, 2010
5B7C
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BU of 5b7c by Molmil
Crystal structure of octopus S-crystallin Q108F mutant in complex with glutathione
Descriptor: GLUTATHIONE, S-crystallin OctvuS4, SULFATE ION
Authors:Chou, C.-Y, Tan, W.-H, Wu, C.-G.
Deposit date:2016-06-07
Release date:2016-08-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of a Highly Active Cephalopod S-crystallin Mutant: New Molecular Evidence for Evolution from an Active Enzyme into Lens-Refractive Protein.
Sci Rep, 6, 2016
8G1U
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BU of 8g1u by Molmil
Structure of the methylosome-Lsm10/11 complex
Descriptor: ADENOSINE, Methylosome protein 50, Methylosome subunit pICln, ...
Authors:Lin, M, Paige, A, Tong, L.
Deposit date:2023-02-03
Release date:2023-08-23
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:In vitro methylation of the U7 snRNP subunits Lsm11 and SmE by the PRMT5/MEP50/pICln methylosome.
Rna, 29, 2023
5KS8
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BU of 5ks8 by Molmil
Crystal structure of two-subunit pyruvate carboxylase from Methylobacillus flagellatus
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, MANGANESE (II) ION, PYRUVIC ACID, ...
Authors:Choi, P.H, Tong, L.
Deposit date:2016-07-07
Release date:2016-10-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:A distinct holoenzyme organization for two-subunit pyruvate carboxylase.
Nat Commun, 7, 2016
4UMK
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BU of 4umk by Molmil
The complex of Spo0J and parS DNA in chromosomal partition system
Descriptor: DNA, PROBABLE CHROMOSOME-PARTITIONING PROTEIN PARB, SULFATE ION
Authors:Chen, B.W, Chu, C.H, Tung, J.Y, Hsu, C.E, Hsiao, C.D, Sun, Y.J.
Deposit date:2014-05-19
Release date:2015-05-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.096 Å)
Cite:Insights into ParB spreading from the complex structure of Spo0J and parS.
Proc. Natl. Acad. Sci. U.S.A., 112, 2015
6AP0
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BU of 6ap0 by Molmil
Crystal structure of human FLASH N-terminal domain C54S/C83A (Crystal form 2)
Descriptor: CASP8-associated protein 2
Authors:Aik, W.S, Tong, L.
Deposit date:2017-08-16
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.581 Å)
Cite:The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing.
PLoS ONE, 12, 2017
5ZDE
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BU of 5zde by Molmil
Crystal structure of poly(ADP-ribose) glycohydrolase (PARG) from Deinococcus radiodurans in complex with ADP-ribose (P3221)
Descriptor: Poly ADP-ribose glycohydrolase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Cho, C.C, Hsu, C.H.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2020-03-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans.
Nat Commun, 10, 2019
5ZDA
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BU of 5zda by Molmil
Crystal structure of poly(ADP-ribose) glycohydrolase (PARG) from Deinococcus radiodurans in apo form
Descriptor: SULFATE ION, poly ADP-ribose glycohydrolase
Authors:Cho, C.C, Hsu, C.H.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.548 Å)
Cite:Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans.
Nat Commun, 10, 2019
5ZDC
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BU of 5zdc by Molmil
Crystal structure of poly(ADP-ribose) glycohydrolase (PARG) from Deinococcus radiodurans in complex with ADP-ribose (P32)
Descriptor: PHOSPHATE ION, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, poly ADP-ribose glycohydrolase
Authors:Cho, C.C, Hsu, C.H.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.979 Å)
Cite:Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans.
Nat Commun, 10, 2019
6AOZ
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BU of 6aoz by Molmil
Crystal structure of human FLASH N-terminal domain C54S/C83A (Crystal form 1)
Descriptor: 1,2-ETHANEDIOL, CASP8-associated protein 2
Authors:Aik, W.S, Tong, L.
Deposit date:2017-08-16
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing.
PLoS ONE, 12, 2017
5ZDG
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BU of 5zdg by Molmil
Crystal structure of poly(ADP-ribose) glycohydrolase (PARG) T267R mutant from Deinococcus radiodurans in complex with ADP-ribose
Descriptor: Poly APD-ribose glycohydrolase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Cho, C.C, Hsu, C.H.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2020-03-11
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans.
Nat Commun, 10, 2019
5ZDB
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BU of 5zdb by Molmil
Crystal structure of poly(ADP-ribose) glycohydrolase (PARG) from Deinococcus radiodurans in complex with ADP-ribose (P21)
Descriptor: Poly ADP-ribose glycohydrolase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
Authors:Cho, C.C, Hsu, C.H.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.972 Å)
Cite:Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans.
Nat Commun, 10, 2019

 

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數據於2024-11-06公開中

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