8OQ3
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![BU of 8oq3 by Molmil](/molmil-images/mine/8oq3) | Structure of methylamine treated human complement C3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Gadeberg, T.A.F, Andersen, G.R. | Deposit date: | 2023-04-11 | Release date: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of methylamine treated human complement C3 To Be Published
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6EHG
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![BU of 6ehg by Molmil](/molmil-images/mine/6ehg) | complement component C3b in complex with a nanobody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jensen, R.K, Andersen, K.R, Gadeberg, T.A.F, Laursen, N.S, Andersen, G.R. | Deposit date: | 2017-09-13 | Release date: | 2018-02-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement. J. Biol. Chem., 293, 2018
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7ASC
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![BU of 7asc by Molmil](/molmil-images/mine/7asc) | TGFBIp mutant A546T | Descriptor: | Transforming growth factor-beta-induced protein ig-h3 | Authors: | Andersen, G.R, Nielsen, N.S, Gadeberg, T.A.F. | Deposit date: | 2020-10-27 | Release date: | 2020-12-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.8 Å) | Cite: | Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy. J.Biol.Chem., 297, 2021
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7ASG
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![BU of 7asg by Molmil](/molmil-images/mine/7asg) | TGFBIp mutant R555W | Descriptor: | Transforming growth factor-beta-induced protein ig-h3 | Authors: | Nielsen, N.S, Gadeberg, T.A.F, Andersen, G.R. | Deposit date: | 2020-10-27 | Release date: | 2020-12-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy. J.Biol.Chem., 297, 2021
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7AS7
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![BU of 7as7 by Molmil](/molmil-images/mine/7as7) | |
6RUR
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![BU of 6rur by Molmil](/molmil-images/mine/6rur) | Structure of the SCIN stabilized C3bBb convertase bound to properdin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, ... | Authors: | Pedersen, D.V, Gadeberg, T.A.F, Andersen, G.R. | Deposit date: | 2019-05-29 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (6 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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7NOZ
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![BU of 7noz by Molmil](/molmil-images/mine/7noz) | Structure of the nanobody stablized properdin bound alternative pathway proconvertase C3b:FB:FP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 alpha chain, Complement C3 beta chain, ... | Authors: | Lorenzen, J, Pedersen, D.V, Andersen, G.R. | Deposit date: | 2021-02-26 | Release date: | 2022-07-27 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structure determination of an unstable macromolecular complex enabled by nanobody-peptide bridging. Protein Sci., 31, 2022
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6XZU
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![BU of 6xzu by Molmil](/molmil-images/mine/6xzu) | |
6RV6
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![BU of 6rv6 by Molmil](/molmil-images/mine/6rv6) | Structure of properdin lacking TSR3 based on anomalous data | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, alpha-D-mannopyranose, ... | Authors: | Pedersen, D.V, Andersen, G.R. | Deposit date: | 2019-05-31 | Release date: | 2019-08-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.507 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6SEJ
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![BU of 6sej by Molmil](/molmil-images/mine/6sej) | Structure of a functional monomeric properdin lacking TSR3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, alpha-D-mannopyranose, ... | Authors: | Pedersen, D.V, Andersen, G.R. | Deposit date: | 2019-07-30 | Release date: | 2019-08-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.501 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6RU5
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![BU of 6ru5 by Molmil](/molmil-images/mine/6ru5) | human complement C3 in complex with the hC3Nb1 nanobody | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Jensen, R.K, Andersen, G.R. | Deposit date: | 2019-05-27 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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6RU3
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![BU of 6ru3 by Molmil](/molmil-images/mine/6ru3) | |
6RUV
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![BU of 6ruv by Molmil](/molmil-images/mine/6ruv) | |
6RUS
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![BU of 6rus by Molmil](/molmil-images/mine/6rus) | Structure of a functional properdin monomer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Properdin, SULFATE ION, ... | Authors: | Pedersen, D.V, Andersen, G.R. | Deposit date: | 2019-05-29 | Release date: | 2019-08-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System. Front Immunol, 10, 2019
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