7ASG

TGFBIp mutant R555W

Summary for 7ASG

Entry DOI	10.2210/pdb7asg/pdb
Related	5nv6
Descriptor	Transforming growth factor-beta-induced protein ig-h3 (2 entities in total)
Functional Keywords	granular corneal dystrophy, lattice corneal dystrophy, protein aggregation, extracellular matrix protein, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	65132.38
Authors	Nielsen, N.S.,Gadeberg, T.A.F.,Andersen, G.R. (deposition date: 2020-10-27, release date: 2020-12-23, Last modification date: 2024-01-31)
Primary citation	Nielsen, N.S.,Gadeberg, T.A.F.,Poulsen, E.T.,Harwood, S.L.,Weberskov, C.E.,Pedersen, J.S.,Andersen, G.R.,Enghild, J.J. Mutation-induced dimerization of transforming growth factor-beta-induced protein may drive protein aggregation in granular corneal dystrophy. J.Biol.Chem., 297:100858-100858, 2021 Cited by PubMed: 34097874 DOI: 10.1016/j.jbc.2021.100858 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation