4G6S
 
 | | Minimal Hairpin Ribozyme in the Transition State with A38P Variation | | Descriptor: | COBALT HEXAMMINE(III), Loop A Substrate strand, Loop A and Loop B Ribozyme strand, ... | | Authors: | Liberman, J.A, Jenkins, J.L, Krucinska, J, Wedekind, J.E. | | Deposit date: | 2012-07-19 | | Release date: | 2012-08-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.84 Å) | | Cite: | A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis.
J.Am.Chem.Soc., 134, 2012
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7CJG
 | | Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase | | Descriptor: | 5,6-DIMETHYLBENZIMIDAZOLE, GLYCEROL, Glutamine cyclotransferase-related protein, ... | | Authors: | Ruiz-Carrillo, D, Lamers, S, Feng, Q, Yu, S, Sun, B, Jiang, J, Lukman, M. | | Deposit date: | 2020-07-10 | | Release date: | 2021-05-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase.
Biol.Chem., 402, 2021
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6K2L
 | | Crystal structure of the Siderophore-interacting protein SipS from Aeromonas hydrophila | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Siderophore-interacting protein | | Authors: | Shang, F, Lan, J, Liu, W, Xu, Y. | | Deposit date: | 2019-05-14 | | Release date: | 2019-06-12 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the Siderophore-interacting protein SIP from Aeromonas hydrophila.
Biochem.Biophys.Res.Commun., 519, 2019
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7CJE
 | | Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase | | Descriptor: | GLYCEROL, Glutamine cyclotransferase-related protein, MAGNESIUM ION, ... | | Authors: | Ruiz-Carrillo, D, Lamers, S, Feng, Q, Yu, S, Sun, B, Jiang, J, Lukman, M. | | Deposit date: | 2020-07-10 | | Release date: | 2021-05-05 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.950007 Å) | | Cite: | Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase.
Biol.Chem., 402, 2021
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7C4D
 | | Marine microorganism esterase | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Putative esterase, ... | | Authors: | Zhu, C.H, Wu, Y.K, Isupov, M.N. | | Deposit date: | 2020-05-16 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structural Insights into a Novel Esterase from the East Pacific Rise and Its Improved Thermostability by a Semirational Design.
J.Agric.Food Chem., 69, 2021
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2M3C
 | | Solution Structure of gammaM7-Crystallin | | Descriptor: | Crystallin, gamma M7 | | Authors: | Mahler, B, Wu, Z. | | Deposit date: | 2013-01-16 | | Release date: | 2013-08-28 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and Dynamics of the Fish Eye Lens Protein, gamma M7-Crystallin.
Biochemistry, 52, 2013
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6KUK
 | | Structure of influenza D virus polymerase bound to vRNA promoter in mode A conformation (class A1) | | Descriptor: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | Deposit date: | 2019-09-02 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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6KUR
 | | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1) | | Descriptor: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | Deposit date: | 2019-09-02 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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6KUP
 | | Structure of influenza D virus polymerase bound to vRNA promoter in Mode A conformation(Class A2) | | Descriptor: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | Deposit date: | 2019-09-02 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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6KUV
 | | Structure of influenza D virus polymerase bound to cRNA promoter in class 2 | | Descriptor: | 3'-cRNA, 5'-cRNA, Polymerase 3, ... | | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | Deposit date: | 2019-09-02 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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6KUT
 | | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B2) | | Descriptor: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | Deposit date: | 2019-09-02 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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6KV5
 | | Structure of influenza D virus apo polymerase | | Descriptor: | Polymerase 3, Polymerase PB2, RNA-directed RNA polymerase catalytic subunit | | Authors: | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | | Deposit date: | 2019-09-03 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
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7D57
 | | C-Src in complex with FIIN-2 | | Descriptor: | N-(4-{[3-(3,5-dimethoxyphenyl)-7-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl}phenyl)propanamide, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION | | Authors: | Chen, Y.H, Qu, L.Z. | | Deposit date: | 2020-09-25 | | Release date: | 2021-10-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.104 Å) | | Cite: | Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors
Commun Chem, 5, 2022
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6A7B
 | | AKR1C3 complexed with new inhibitor with novel scaffold | | Descriptor: | (4R)-6-amino-4-(4-hydroxy-3-methoxy-5-nitrophenyl)-3-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, Aldo-keto reductase family 1 member C3, DIMETHYLFORMAMIDE, ... | | Authors: | Zheng, X, Zhao, Y, Zhang, H, Chen, Y. | | Deposit date: | 2018-07-02 | | Release date: | 2019-07-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Screening, synthesis, crystal structure, and molecular basis of 6-amino-4-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles as novel AKR1C3 inhibitors.
Bioorg.Med.Chem., 26, 2018
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6L4R
 | | Crystal structure of Enterovirus D68 RdRp | | Descriptor: | RdRp | | Authors: | Wang, M.L, Li, L, Zhang, Y, Chen, Y.P, Su, D. | | Deposit date: | 2019-10-21 | | Release date: | 2020-06-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.147 Å) | | Cite: | Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel.
J.Struct.Biol., 211, 2020
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7XSD
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7D5O
 | | C-Src in complex with TAS-120 | | Descriptor: | 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl]prop-2-en-1-one, Proto-oncogene tyrosine-protein kinase Src | | Authors: | Qu, L.Z, Chen, Y.H. | | Deposit date: | 2020-09-27 | | Release date: | 2021-12-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Structural insights into the potency and selectivity of covalent pan-FGFR inhibitors
Commun Chem, 5, 2022
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7YFW
 | | Cyanophage Pam3 fiber | | Descriptor: | Pam3 fiber proreins | | Authors: | Yang, F, Jiang, Y.L, Zhou, C.Z. | | Deposit date: | 2022-07-09 | | Release date: | 2023-01-18 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.96 Å) | | Cite: | Fine structure and assembly pattern of a minimal myophage Pam3.
Proc.Natl.Acad.Sci.USA, 120, 2023
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7YFZ
 | | Cyanophage Pam3 baseplate proteins | | Descriptor: | Pam3 baseplate wedge gp22, Pam3 baseplate wedge gp23, Pam3 hub gp19, ... | | Authors: | Yang, F, Jiang, Y.L, Zhou, C.Z. | | Deposit date: | 2022-07-09 | | Release date: | 2023-01-18 | | Last modified: | 2023-02-01 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Fine structure and assembly pattern of a minimal myophage Pam3.
Proc.Natl.Acad.Sci.USA, 120, 2023
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4FA7
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7WHT
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7KDT
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7E7G
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7DTZ
 | | FGFR4 complex with a covalent inhibitor | | Descriptor: | Fibroblast growth factor receptor 4, N-[2-[[5-[[2,6-bis(chloranyl)-3,5-dimethoxy-phenyl]methoxy]pyrimidin-2-yl]amino]-3-methyl-phenyl]-2-fluoranyl-prop-2-enamide, SULFATE ION | | Authors: | Chen, X.J, Dai, S.Y, Chen, Y.H. | | Deposit date: | 2021-01-07 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Investigation of Covalent Warheads in the Design of 2-Aminopyrimidine-based FGFR4 Inhibitors.
Acs Med.Chem.Lett., 12, 2021
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4JAM
 | | Crystal structure of broadly neutralizing anti-hiv-1 antibody ch103 | | Descriptor: | 1,2-ETHANEDIOL, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ... | | Authors: | Zhou, T, Moquin, S, Zheng, A, Srivatsan, S, Kwong, P.D. | | Deposit date: | 2013-02-18 | | Release date: | 2013-04-03 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
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