7DSF
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![BU of 7dsf by Molmil](/molmil-images/mine/7dsf) | The Crystal Structure of human SPR from Biortus. | Descriptor: | ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Sepiapterin reductase, ... | Authors: | Wang, F, Lv, Z, Cheng, W, Lin, D, Meng, Q, Zhang, B, Huang, Y. | Deposit date: | 2020-12-31 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Crystal Structure of human SPR from Biortus. To Be Published
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7CAF
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![BU of 7caf by Molmil](/molmil-images/mine/7caf) | Mycobacterium smegmatis LpqY-SugABC complex in the pre-translocation state | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | Deposit date: | 2020-06-08 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7CAG
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![BU of 7cag by Molmil](/molmil-images/mine/7cag) | Mycobacterium smegmatis LpqY-SugABC complex in the catalytic intermediate state | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T. | Deposit date: | 2020-06-08 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7EPK
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![BU of 7epk by Molmil](/molmil-images/mine/7epk) | |
7ESF
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![BU of 7esf by Molmil](/molmil-images/mine/7esf) | The Crystal Structure of human MTH1 from Biortus | Descriptor: | 7,8-dihydro-8-oxoguanine triphosphatase, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL | Authors: | Wang, F, Cheng, W, Shang, H, Wang, R, Zhang, B, Tian, F. | Deposit date: | 2021-05-10 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The Crystal Structure of human MTH1 from Biortus To Be Published
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7CAD
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![BU of 7cad by Molmil](/molmil-images/mine/7cad) | Mycobacterium smegmatis SugABC complex | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | Deposit date: | 2020-06-08 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7CAE
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![BU of 7cae by Molmil](/molmil-images/mine/7cae) | Mycobacterium smegmatis LpqY-SugABC complex in the resting state | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | Deposit date: | 2020-06-08 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7VOK
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![BU of 7vok by Molmil](/molmil-images/mine/7vok) | |
7VMX
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![BU of 7vmx by Molmil](/molmil-images/mine/7vmx) | |
7AP4
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![BU of 7ap4 by Molmil](/molmil-images/mine/7ap4) | Thermus thermophilus Aspartyl-tRNA Synthetase in Complex with Compound AspS7HMDDA | Descriptor: | (3~{S})-3-azanyl-4-[[(2~{R},3~{S},4~{R},5~{R})-5-[7-azanyl-5-(hydroxymethyl)benzimidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxysulfonylamino]-4-oxidanylidene-butanoic acid, Aspartate--tRNA(Asp) ligase | Authors: | De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D. | Deposit date: | 2020-10-15 | Release date: | 2020-12-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors. Molecules, 25, 2020
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6P5Q
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![BU of 6p5q by Molmil](/molmil-images/mine/6p5q) | X-ray structure of Fe(II)-soaked UndA bound to lauric acid | Descriptor: | FE (III) ION, GLYCEROL, LAURIC ACID, ... | Authors: | Rajakovich, L.J, Mitchell, A.J, Boal, A.K. | Deposit date: | 2019-05-30 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Substrate-Triggered Formation of a Peroxo-Fe2(III/III) Intermediate during Fatty Acid Decarboxylation by UndA. J.Am.Chem.Soc., 141, 2019
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7AP2
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![BU of 7ap2 by Molmil](/molmil-images/mine/7ap2) | Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound LeuS7HMDDA | Descriptor: | 1,2-ETHANEDIOL, Leucine--tRNA ligase, MAGNESIUM ION, ... | Authors: | Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. | Deposit date: | 2020-10-15 | Release date: | 2020-10-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors. Molecules, 25, 2020
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7AP3
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![BU of 7ap3 by Molmil](/molmil-images/mine/7ap3) | Crystal structure of E. coli tyrosyl-tRNA synthetase in complex with TyrS7HMDDA | Descriptor: | SODIUM ION, Tyrosine--tRNA ligase, [(2~{R},3~{S},4~{R},5~{R})-5-[7-azanyl-5-(hydroxymethyl)benzimidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[(2~{S})-2-azanyl-3-(4-hydroxyphenyl)propanoyl]sulfamate | Authors: | De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D. | Deposit date: | 2020-10-15 | Release date: | 2020-10-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors. Molecules, 25, 2020
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7AP1
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![BU of 7ap1 by Molmil](/molmil-images/mine/7ap1) | Klebsiella pneumoniae Seryl-tRNA synthetase in Complex with Compound SerS7HMDDA | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Serine-tRNA ligase, ... | Authors: | Pang, L, De Graef, S, Strelkov, S.V, Weeks, S.D. | Deposit date: | 2020-10-15 | Release date: | 2020-11-11 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors. Molecules, 25, 2020
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5I95
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![BU of 5i95 by Molmil](/molmil-images/mine/5i95) | Crystal Structure of Human Mitochondrial Isocitrate Dehydrogenase R140Q Mutant Homodimer bound to NADPH and alpha-Ketoglutaric acid | Descriptor: | 2-OXOGLUTARIC ACID, ACETATE ION, CALCIUM ION, ... | Authors: | Zhang, B, Jin, L, Wu, W, Jiang, F, DeLaBarre, B, Travins, J.A, Padyana, A.K. | Deposit date: | 2016-02-19 | Release date: | 2017-03-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations. Cancer Discov, 7, 2017
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8FIS
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![BU of 8fis by Molmil](/molmil-images/mine/8fis) | Structure of Bispecific CAP256V2LS-J3 Fab in complex with BG505 DS-SOSIP.664 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Gorman, J, Kwong, P.D. | Deposit date: | 2022-12-16 | Release date: | 2023-02-01 | Last modified: | 2023-02-15 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency. Mabs, 15, 2023
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6AAY
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![BU of 6aay by Molmil](/molmil-images/mine/6aay) | the Cas13b binary complex | Descriptor: | Bergeyella zoohelcum Cas13b (R1177A) mutant, RNA (52-MER) | Authors: | Bo, Z, Weiwei, Y, Yangmiao, Y, Ouyang, S.Y. | Deposit date: | 2018-07-19 | Release date: | 2019-03-13 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural insights into Cas13b-guided CRISPR RNA maturation and recognition. Cell Res., 28, 2018
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7XV7
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![BU of 7xv7 by Molmil](/molmil-images/mine/7xv7) | |
4UET
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![BU of 4uet by Molmil](/molmil-images/mine/4uet) | Diversity in the structures and ligand binding sites among the fatty acid and retinol binding proteins of nematodes revealed by Na-FAR-1 from Necator americanus | Descriptor: | NEMATODE FATTY ACID RETINOID BINDING PROTEIN | Authors: | Rey-Burusco, M.F, Ibanez Shimabukuro, M, Griffiths, K, Cooper, A, Kennedy, M.W, Corsico, B, Smith, B.O, Griffiths, K. | Deposit date: | 2014-12-18 | Release date: | 2015-09-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Diversity in the Structures and Ligand Binding Sites of Nematode Fatty Acid and Retinol Binding Proteins Revealed by Na-Far-1 from Necator Americanus. Biochem.J., 471, 2015
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3W8S
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![BU of 3w8s by Molmil](/molmil-images/mine/3w8s) | |
5TVD
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![BU of 5tvd by Molmil](/molmil-images/mine/5tvd) | Crystal structure of Tm16 | Descriptor: | Tm16 | Authors: | Asojo, O.A. | Deposit date: | 2016-11-08 | Release date: | 2017-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.734 Å) | Cite: | Identification, Characterization, and Structure of Tm16 from Trichuris muris. J Parasitol Res, 2017, 2017
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4XCP
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![BU of 4xcp by Molmil](/molmil-images/mine/4xcp) | Fatty Acid and Retinol binding protein Na-FAR-1 from Necator americanus | Descriptor: | Nematode fatty acid retinoid binding protein, PALMITIC ACID | Authors: | Gabrielsen, M, Rey-Burusco, M.F, Ibanez-Shimabukuro, M, Griffiths, K, Kennedy, M.W, Corsico, B, Smith, B.O. | Deposit date: | 2014-12-18 | Release date: | 2015-09-16 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Diversity in the structures and ligand-binding sites of nematode fatty acid and retinol-binding proteins revealed by Na-FAR-1 from Necator americanus. Biochem.J., 471, 2015
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5KX4
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![BU of 5kx4 by Molmil](/molmil-images/mine/5kx4) | Structure of SALO | Descriptor: | 10.7 kDa salivary protein | Authors: | Asojo, O.A. | Deposit date: | 2016-07-20 | Release date: | 2016-07-27 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structure of SALO, a leishmaniasis vaccine candidate from the sand fly Lutzomyia longipalpis. PLoS Negl Trop Dis, 11, 2017
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6L5M
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![BU of 6l5m by Molmil](/molmil-images/mine/6l5m) | Crystal structure of human DEAD-box RNA helicase DDX21 in complex with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Nucleolar RNA helicase 2 | Authors: | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | Deposit date: | 2019-10-24 | Release date: | 2020-06-17 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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6L5L
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![BU of 6l5l by Molmil](/molmil-images/mine/6l5l) | Crystal structure of human DEAD-box RNA helicase DDX21 at apo state | Descriptor: | MAGNESIUM ION, Nucleolar RNA helicase 2 | Authors: | Chen, Z.J, Hu, X.J, Zhou, Z, Li, J.X. | Deposit date: | 2019-10-24 | Release date: | 2020-06-17 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation. Adv Sci, 7, 2020
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