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7OQD
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BU of 7oqd by Molmil
A single sulfatase is required for metabolism of colonic mucin O-glycans and intestinal colonization by a symbiotic human gut bacterium (BT1636-S1_20)
Descriptor: 3-O-sulfo-beta-D-galactopyranose, Arylsulfatase, CALCIUM ION
Authors:Sofia de Jesus Vaz Luis, A, Basle, A, Martens, E.C, Cartmell, A.
Deposit date:2021-06-03
Release date:2021-10-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A single sulfatase is required to access colonic mucin by a gut bacterium.
Nature, 598, 2021
1IVD
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BU of 1ivd by Molmil
STRUCTURES OF AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(ACETYLAMINO)-3-HYDROXY-5-NITROBENZOIC ACID, CALCIUM ION, ...
Authors:Jedrzejas, M.J, Luo, M.
Deposit date:1994-12-12
Release date:1995-03-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of aromatic inhibitors of influenza virus neuraminidase.
Biochemistry, 34, 1995
1IVE
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BU of 1ive by Molmil
STRUCTURES OF AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(ACETYLAMINO)-3-AMINO BENZOIC ACID, ...
Authors:Jedrzejas, M.J, Luo, M.
Deposit date:1994-12-12
Release date:1995-03-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of aromatic inhibitors of influenza virus neuraminidase.
Biochemistry, 34, 1995
6U3Z
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BU of 6u3z by Molmil
Structure of VD20_5A4 Fab
Descriptor: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
Authors:Dionne, G, Shapiro, L.
Deposit date:2019-08-22
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.99002314 Å)
Cite:Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.
J.Exp.Med., 217, 2020
6XRE
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BU of 6xre by Molmil
Structure of the p53/RNA polymerase II assembly
Descriptor: Cellular tumor antigen p53, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ...
Authors:Liou, S.-H, Singh, S, Singer, R.H, Coleman, R.A, Liu, W.
Deposit date:2020-07-12
Release date:2021-03-24
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of the p53/RNA polymerase II assembly.
Commun Biol, 4, 2021
7TZ2
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BU of 7tz2 by Molmil
Structure of human Fibrinogen-like protein 1
Descriptor: CALCIUM ION, Fibrinogen-like protein 1
Authors:Ming, Q, Tran, T.H, Luca, V.C.
Deposit date:2022-02-15
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
7TZH
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BU of 7tzh by Molmil
Structure of human LAG3 domains 3-4 in complex with antibody single chain-variable fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, scFvF7
Authors:Ming, Q, Tran, T.H, Luca, V.C.
Deposit date:2022-02-15
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
7TZE
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BU of 7tze by Molmil
Structure of murine LAG3 domains 1-2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein
Authors:Ming, Q, Tran, T.H, Luca, V.C.
Deposit date:2022-02-15
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
7TZG
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BU of 7tzg by Molmil
Structure of human LAG3 in complex with antibody single-chain variable fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, scFvF7
Authors:Ming, Q, Tran, T.H, Luca, V.C.
Deposit date:2022-02-15
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
6EF4
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BU of 6ef4 by Molmil
Crystal structure of mouse PP2A Aalpha P179R mutant
Descriptor: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
Authors:Wang, Z, Shen, G, Xu, W.
Deposit date:2018-08-16
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The Highly Recurrent PP2A A alpha-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis.
Cancer Res., 79, 2019
5NG0
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BU of 5ng0 by Molmil
Structure of RIP2K(L294F) with bound AMPPCP
Descriptor: COBALT (II) ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Pellegrini, E, Cusack, S.
Deposit date:2017-03-16
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.
PLoS ONE, 12, 2017
5NG3
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BU of 5ng3 by Molmil
Structure of inactive kinase RIP2K(K47R)
Descriptor: Receptor-interacting serine/threonine-protein kinase 2, SULFATE ION
Authors:Pellegrini, E, Cusack, S.
Deposit date:2017-03-16
Release date:2017-06-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.
PLoS ONE, 12, 2017
5NG2
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BU of 5ng2 by Molmil
Structure of RIP2K(D146N) with bound Staurosporine
Descriptor: PHOSPHATE ION, Receptor-interacting serine/threonine-protein kinase 2, STAUROSPORINE
Authors:Pellegrini, E, Cusack, S.
Deposit date:2017-03-16
Release date:2017-06-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation.
PLoS ONE, 12, 2017
8GI7
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BU of 8gi7 by Molmil
C143A variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, citrate synthase (unknown stereospecificity)
Authors:Pathirage, R, Ronning, D.
Deposit date:2023-03-13
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GM9
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BU of 8gm9 by Molmil
Structure of Citrate Synthase(CitA) in Mycobacterium Tuberculosis
Descriptor: 1,2-ETHANEDIOL, ACRYLIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Pathirage, R, Ronning, D, Favrot, L.
Deposit date:2023-03-24
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GMI
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BU of 8gmi by Molmil
Citrate Synthase (CitA) in Mycobacterium tuberculosis modified by Ebselen at C143 residue
Descriptor: CITRATE ANION, N-phenyl-2-selanylbenzamide, citrate synthase
Authors:Pathirage, R, Ronning, D.
Deposit date:2023-03-25
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GLL
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BU of 8gll by Molmil
R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
Authors:Pathirage, R, Ronning, D, Petit, C.
Deposit date:2023-03-22
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GMF
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BU of 8gmf by Molmil
R153M variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Descriptor: citrate synthase
Authors:Pathirage, R, Ronning, D.
Deposit date:2023-03-25
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GIW
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BU of 8giw by Molmil
C143K variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ...
Authors:Pathirage, R, Ronning, D.
Deposit date:2023-03-14
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GLB
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BU of 8glb by Molmil
Selenomethionine Derivatized Citrate Synthase (CitA) in Mycobacterium tuberculosis with Pyruvate
Descriptor: 1,2-ETHANEDIOL, PYRUVIC ACID, citrate synthase
Authors:Pathirage, R, Ronning, D, Favrot, L.
Deposit date:2023-03-21
Release date:2023-06-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GMK
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BU of 8gmk by Molmil
Pyruvate bound structure of Citrate Synthase (CitA) in Mycobacterium Tuberculosis
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PYRUVIC ACID, ...
Authors:Pathirage, R, Ronning, D, Yamsek, M.
Deposit date:2023-03-26
Release date:2023-06-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8E90
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BU of 8e90 by Molmil
Inhibition of Human Menin by SNDX-5613
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-({4-[7-({(1r,4r)-4-[(ethanesulfonyl)amino]cyclohexyl}methyl)-2,7-diazaspiro[3.5]nonan-2-yl]pyrimidin-5-yl}oxy)-N-ethyl-5-fluoro-N-(propan-2-yl)benzamide, ...
Authors:McKeever, B.M, KULKARNI, S, McGeehan, G.M.
Deposit date:2022-08-26
Release date:2022-12-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:MEN1 mutations mediate clinical resistance to menin inhibition.
Nature, 615, 2023
1IVC
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BU of 1ivc by Molmil
STRUCTURES OF AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(ACETYLAMINO)-5-AMINO-3-HYDROXYBENZOIC ACID, CALCIUM ION, ...
Authors:Jedrzejas, M.J, Luo, M.
Deposit date:1994-12-12
Release date:1995-03-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of aromatic inhibitors of influenza virus neuraminidase.
Biochemistry, 34, 1995
5K9M
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BU of 5k9m by Molmil
Crystal Structure of PriB Binary Complex with Product Diphosphate
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PYROPHOSPHATE 2-, PriB Prenyltransferase
Authors:Cao, H, Elshahawi, S, Benach, J, Wasserman, S.R, Morisco, L.L, Koss, J.W, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2016-06-01
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure and specificity of a permissive bacterial C-prenyltransferase.
Nat. Chem. Biol., 13, 2017
5JXM
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BU of 5jxm by Molmil
Crystal Structure of Prenyltransferase PriB Apo Form
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, PriB
Authors:Cao, H, Elshahawi, S, Benach, J, Wasserman, S.R, Morisco, L.L, Koss, J.W, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2016-05-13
Release date:2016-06-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Structure and specificity of a permissive bacterial C-prenyltransferase.
Nat. Chem. Biol., 13, 2017

221051

數據於2024-06-12公開中

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