5NG0

Structure of RIP2K(L294F) with bound AMPPCP

Summary for 5NG0

Entry DOI	10.2210/pdb5ng0/pdb
Descriptor	Receptor-interacting serine/threonine-protein kinase 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	rip2k, kinase, active state, amppcpp, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	70809.90
Authors	Pellegrini, E.,Cusack, S. (deposition date: 2017-03-16, release date: 2017-06-07, Last modification date: 2024-01-17)
Primary citation	Pellegrini, E.,Signor, L.,Singh, S.,Boeri Erba, E.,Cusack, S. Structures of the inactive and active states of RIP2 kinase inform on the mechanism of activation. PLoS ONE, 12:e0177161-e0177161, 2017 Cited by PubMed: 28545134 DOI: 10.1371/journal.pone.0177161 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation