5NG0
Structure of RIP2K(L294F) with bound AMPPCP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Receptor-interacting serine/threonine-protein kinase 2 | polymer | 304 | 34846.0 | 2 | UniProt (O43353) Pfam (PF07714) In PDB | Homo sapiens (Human) | CARD-containing interleukin-1 beta-converting enzyme-associated kinase,CARD-containing IL-1 beta ICE-kinase,RIP-like-interacting CLARP kinase,Receptor-interacting protein 2,RIP-2,Tyrosine-protein kinase RIPK2 |
| 2 | A, B | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 2 | Chemie (ACP) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | B | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 5 | water | water | 18.0 | 397 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: O43353)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Phe 294 | Leu 294 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69691.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1118.0 | |
| All* | Total formula weight | 70809.9 |
