8I35
 
 | | Acyl-ACP synthetase structure bound to oleic acid | | Descriptor: | Acyl-acyl carrier protein synthetase, OLEIC ACID | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-16 | | Release date: | 2024-01-24 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.75 Å) | | Cite: | Acyl-ACP synthetase structure bound to oleic acid
To Be Published
|
|
8I51
 | | Acyl-ACP synthetase structure bound to AMP-MC7 | | Descriptor: | 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, ... | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-21 | | Release date: | 2024-01-24 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.76 Å) | | Cite: | Acyl-ACP synthetase structure bound to AMP-MC7
To Be Published
|
|
8I3I
 | | Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2 | | Descriptor: | Acyl-acyl carrier protein synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-17 | | Release date: | 2024-01-24 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.68 Å) | | Cite: | Acyl-ACP synthetase structure bound to AMP-PNP in the presence of MgCl2
To Be Published
|
|
8HZX
 | | Acyl-ACP synthetase structure-2 | | Descriptor: | Acyl-acyl carrier protein synthetase | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-09 | | Release date: | 2024-01-24 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.68 Å) | | Cite: | Acyl-ACP synthetase structure-2
To Be Published
|
|
8I6M
 | | Acyl-ACP synthetase structure bound to AMP-C18:1 | | Descriptor: | ADENOSINE MONOPHOSPHATE, Acyl-acyl carrier protein synthetase, MAGNESIUM ION, ... | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-28 | | Release date: | 2024-01-31 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.59 Å) | | Cite: | Acyl-ACP synthetase structure bound to AMP-C18:1
To Be Published
|
|
8I49
 | | Acyl-ACP synthetase structure bound to ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Acyl-acyl carrier protein synthetase | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-01-18 | | Release date: | 2024-01-24 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.41 Å) | | Cite: | Acyl-ACP synthetase structure bound to ATP.
To Be Published
|
|
8I8D
 | | Acyl-ACP synthetase structure bound to MC7-ACP | | Descriptor: | 7-methoxy-7-oxidanylidene-heptanoic acid, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ... | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-02-03 | | Release date: | 2024-02-07 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.51 Å) | | Cite: | Acyl-ACP synthetase structure bound to MC7-ACP
To Be Published
|
|
8I8E
 | | Acyl-ACP synthetase structure bound to C18:1-ACP | | Descriptor: | 4'-PHOSPHOPANTETHEINE, ADENOSINE MONOPHOSPHATE, Acyl carrier protein, ... | | Authors: | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | | Deposit date: | 2023-02-04 | | Release date: | 2024-02-07 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (2.63 Å) | | Cite: | Acyl-ACP synthetase structure bound to C18:1-ACP
To Be Published
|
|
4XRX
 | | Crystal structure of a metabolic reductase with (E)-5-((1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)pyridin-2(1H)-one | | Descriptor: | 5-[(E)-(1-methyl-5-oxo-2-thioxoimidazolidin-4-ylidene)methyl]pyridin-2(1H)-one, Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Zheng, B, Wu, F, Jiang, H, Kogiso, M, Yao, Y, Zhou, C, Li, X, Song, Y. | | Deposit date: | 2015-01-21 | | Release date: | 2015-12-09 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
J.Med.Chem., 58, 2015
|
|
4Z8Q
 | | CRYSTAL STRUCTURE OF AvrRxo1-ORF1:AvrRxo1-ORF2 COMPLEX, SELENOMETHIONINE SUBSTITUTED. | | Descriptor: | AvrRxo1-ORF1, AvrRxo1-ORF2, PHOSPHATE ION | | Authors: | Han, Q, Zhou, C, Wu, S, Liu, Y, Yang, Z, Miao, J, Triplett, L, Cheng, Q, Tokuhisa, J, Deblais, L, Robinson, H, Leach, J.E, Li, J, Zhao, B. | | Deposit date: | 2015-04-09 | | Release date: | 2015-09-23 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Crystal Structure of Xanthomonas AvrRxo1-ORF1, a Type III Effector with a Polynucleotide Kinase Domain, and Its Interactor AvrRxo1-ORF2.
Structure, 23, 2015
|
|
4Z8T
 | | CRYSTAL STRUCTURE OF AvrRxo1-ORF1:AvrRxo1-ORF2 WITH SULPHATE IONS | | Descriptor: | ACETATE ION, AvrRxo1-ORF1, AvrRxo1-ORF2, ... | | Authors: | Han, Q, Zhou, C, Wu, S, Liu, Y, Yang, Z, Miao, J, Triplett, L, Cheng, Q, Tokuhisa, J, Deblais, L, Robinson, H, Leach, J.E, Li, J, Zhao, B. | | Deposit date: | 2015-04-09 | | Release date: | 2015-09-23 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Crystal Structure of Xanthomonas AvrRxo1-ORF1, a Type III Effector with a Polynucleotide Kinase Domain, and Its Interactor AvrRxo1-ORF2.
Structure, 23, 2015
|
|
4Z8V
 | | CRYSTAL STRUCTURE OF AVRRXO1-ORF1:-ORF2 COMPLEX, NATIVE. | | Descriptor: | AvrRxo1-ORF1, AvrRxo1-ORF2, PHOSPHATE ION | | Authors: | Han, Q, Zhou, C, Wu, S, Liu, Y, Yang, Z, Miao, J, Triplett, L, Cheng, Q, Tokuhisa, J, Deblais, L, Robinson, H, Leach, J.E, Li, J, Zhao, B. | | Deposit date: | 2015-04-09 | | Release date: | 2015-09-23 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of Xanthomonas AvrRxo1-ORF1, a Type III Effector with a Polynucleotide Kinase Domain, and Its Interactor AvrRxo1-ORF2.
Structure, 23, 2015
|
|
4Z8U
 | | CRYSTAL STRUCTURE OF AvrRxo1-ORF1:-ORF2 WITH ATP | | Descriptor: | ACETATE ION, AvrRxo1-ORF1, AvrRxo1-ORF2, ... | | Authors: | Han, Q, Zhou, C, Wu, S, Liu, Y, Yang, Z, Miao, J, Triplett, L, Cheng, Q, Tokuhisa, J, Deblais, L, Robinson, H, Leach, J.E, Li, J, Zhao, B. | | Deposit date: | 2015-04-09 | | Release date: | 2015-09-23 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal Structure of Xanthomonas AvrRxo1-ORF1, a Type III Effector with a Polynucleotide Kinase Domain, and Its Interactor AvrRxo1-ORF2.
Structure, 23, 2015
|
|
5BY4
 | |
1IMQ
 | | COLICIN E9 IMMUNITY PROTEIN IM9, NMR, MINIMIZED AVERAGE STRUCTURE | | Descriptor: | IM9 | | Authors: | Osborne, M.J, Breeze, A.L, Lian, L.Y, Reilly, A, James, R, Kleanthous, C, Moore, G.R. | | Deposit date: | 1996-05-30 | | Release date: | 1997-07-07 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional solution structure and 13C nuclear magnetic resonance assignments of the colicin E9 immunity protein Im9.
Biochemistry, 35, 1996
|
|
1IMP
 | | COLICIN E9 IMMUNITY PROTEIN IM9, NMR, 21 STRUCTURES | | Descriptor: | IM9 | | Authors: | Osborne, M.J, Breeze, A.L, Lian, L.-Y, Reilly, A, James, R, Kleanthous, C, Moore, G.R. | | Deposit date: | 1996-05-30 | | Release date: | 1997-09-17 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Three-dimensional solution structure and 13C nuclear magnetic resonance assignments of the colicin E9 immunity protein Im9.
Biochemistry, 35, 1996
|
|
4DW6
 | | Novel N-phenyl-phenoxyacetamide derivatives as potential EthR inhibitors and ethionamide boosters. Discovery and optimization using High-Throughput Synthesis. | | Descriptor: | AMMONIUM ION, GLYCEROL, HTH-type transcriptional regulator EthR, ... | | Authors: | Flipo, M, Willand, N, Lecat-Guillet, N, Hounsou, C, Desroses, M, Leroux, F, Lens, Z, Villeret, V, Wohlkonig, A, Wintjens, R, Christophe, T, Jeon, H.K, Locht, C, Brodin, P, Baulard, A.R, Deprez, B. | | Deposit date: | 2012-02-24 | | Release date: | 2013-03-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis.
J.Med.Chem., 55, 2012
|
|
2VAN
 | | Nucleotidyl Transfer Mechanism of Mismatched dNTP Incorporation by DNA Polymerase b by Structural and Kinetic Analyses | | Descriptor: | DNA POLYMERSE BETA | | Authors: | Chan, H, Chou, C, Tang, K, Niebuhr, M, Tung, C, Tsai, M. | | Deposit date: | 2007-09-03 | | Release date: | 2008-04-15 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Mismatched Dntp Incorporation by DNA Polymerase Beta Does not Proceed Via Globally Different Conformational Pathways.
Nucleic Acids Res., 36, 2008
|
|
3VMV
 | | Crystal structure of pectate lyase Bsp165PelA from Bacillus sp. N165 | | Descriptor: | Pectate lyase, SULFATE ION | | Authors: | Zheng, Y, Huang, C.H, Liu, W, Ko, T.P, Xue, Y, Zhou, C, Zhang, G, Guo, R.T, Ma, Y. | | Deposit date: | 2011-12-16 | | Release date: | 2012-07-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5.
Biochem.Biophys.Res.Commun., 420, 2012
|
|
3VMW
 | | Crystal structure of pectate lyase Bsp165PelA from Bacillus sp. N165 in complex with trigalacturonate | | Descriptor: | Pectate lyase, SULFATE ION, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | | Authors: | Zheng, Y, Huang, C.H, Liu, W, Ko, T.P, Xue, Y, Zhou, C, Zhang, G, Guo, R.T, Ma, Y. | | Deposit date: | 2011-12-17 | | Release date: | 2012-07-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5.
Biochem.Biophys.Res.Commun., 420, 2012
|
|
2W8B
 | | Crystal structure of processed TolB in complex with Pal | | Descriptor: | ACETATE ION, GLYCEROL, PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN, ... | | Authors: | Sharma, A, Bonsor, D.A, Kleanthous, C. | | Deposit date: | 2009-01-15 | | Release date: | 2009-02-17 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Allosteric Beta-Propeller Signalling in Tolb and its Manipulation by Translocating Colicins.
Embo J., 28, 2009
|
|
8GXE
 | | PTPN21 FERM PTP complex | | Descriptor: | CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 21 | | Authors: | Chen, L, Zheng, Y.Y, Zhou, C. | | Deposit date: | 2022-09-19 | | Release date: | 2023-09-27 | | Last modified: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural analysis of PTPN21 reveals a dominant-negative effect of the FERM domain on its phosphatase activity.
Sci Adv, 10, 2024
|
|
1FSJ
 | | CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN | | Descriptor: | COLICIN E9, PHOSPHATE ION, ZINC ION | | Authors: | Kuhlmann, U.C, Pommer, A.J, Moore, G.R, James, R, Kleanthous, C, Hemmings, A.M. | | Deposit date: | 2000-09-11 | | Release date: | 2003-06-17 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of the E9 DNase domain in comparison with the inhibited structure of the E9 DNase/Im9 complex
To be Published
|
|
1FR2
 | | CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9(E41A) | | Descriptor: | COLICIN E9, COLICIN E9 IMMUNITY PROTEIN, PHOSPHATE ION, ... | | Authors: | Kuhlmann, U.C, Pommer, A.J, Moore, G.M, James, R, Kleanthous, C, Hemmings, A.M. | | Deposit date: | 2000-09-07 | | Release date: | 2003-06-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | CRYSTAL STRUCTURE OF THE E9 DNASE DOMAIN WITH A MUTANT IMMUNITY PROTEIN IM9(E41A)
To be Published
|
|
7DME
 | | Solution structure of human Aha1 | | Descriptor: | Activator of 90 kDa heat shock protein ATPase homolog 1 | | Authors: | Hu, H, Zhou, C, Zhang, N. | | Deposit date: | 2020-12-03 | | Release date: | 2021-04-21 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Aha1 Exhibits Distinctive Dynamics Behavior and Chaperone-Like Activity.
Molecules, 26, 2021
|
|
