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6VI3
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BU of 6vi3 by Molmil
Straight Filament from Alzheimer's Disease Human Brain Tissue
Descriptor: GLYCINE, Microtubule-associated protein tau
Authors:Arakhamia, T, Lee, C.E, Carlomagno, Y, Duong, D.M, Kundinger, S.R, Wang, K, Williams, D, DeTure, M, Dickson, D.W, Cook, C.N, Seyfried, N.T, Petrucelli, L, Fitzpatrick, A.W.P.
Deposit date:2020-01-11
Release date:2020-04-15
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains
Cell, 180, 2020
7NCJ
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BU of 7ncj by Molmil
Type 2AB alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1
Descriptor: Alpha-synuclein
Authors:Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
Deposit date:2021-01-28
Release date:2021-02-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.23 Å)
Cite:Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCG
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BU of 7ncg by Molmil
Type 2A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2
Descriptor: Alpha-synuclein
Authors:Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
Deposit date:2021-01-28
Release date:2021-02-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCI
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BU of 7nci by Molmil
Type 2B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1
Descriptor: Alpha-synuclein
Authors:Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
Deposit date:2021-01-28
Release date:2021-02-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCH
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BU of 7nch by Molmil
Type 1B alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 1
Descriptor: Alpha-synuclein
Authors:Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
Deposit date:2021-01-28
Release date:2021-02-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCK
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BU of 7nck by Molmil
Type 3 alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 5
Descriptor: Alpha-synuclein
Authors:Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
Deposit date:2021-01-28
Release date:2021-02-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
7NCA
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BU of 7nca by Molmil
Type 1A alpha-synuclein filament seeded in vitro by filaments purified from Multiple Systems Atrophy Case 2
Descriptor: Alpha-synuclein
Authors:Lovestam, S.K.A, Schweighauser, M, Scheres, S.H.W.
Deposit date:2021-01-28
Release date:2021-02-24
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Seeded assembly in vitro does not replicate the structures of alpha-synuclein filaments from multiple system atrophy.
Febs Open Bio, 11, 2021
8QJJ
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BU of 8qjj by Molmil
CTE type II (tau intermediate amyloid)
Descriptor: Isoform Tau-D of Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2023-09-13
Release date:2023-10-18
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Disease-specific tau filaments assemble via polymorphic intermediates.
Nature, 625, 2024
7QWL
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BU of 7qwl by Molmil
TMEM106B filaments with Fold IIb from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVC
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BU of 7qvc by Molmil
TMEM106B filaments with Fold I from Alzheimer's disease (case 1)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QVF
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BU of 7qvf by Molmil
TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-21
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWG
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BU of 7qwg by Molmil
TMEM106B filaments with Fold IIa from Multiple system atrophy (case 19)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QWM
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BU of 7qwm by Molmil
TMEM106B filaments with Fold III from Multiple system atrophy (case 17)
Descriptor: Transmembrane protein 106B
Authors:Lovestam, S, Schweighauser, M, Scheres, S.H.W.
Deposit date:2022-01-25
Release date:2022-03-09
Last modified:2022-05-25
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Age-dependent formation of TMEM106B amyloid filaments in human brains.
Nature, 605, 2022
7QJW
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BU of 7qjw by Molmil
In vitro assembled tau filaments with structures like chronic traumatic encephalopathy type II (8a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-01-19
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKF
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BU of 7qkf by Molmil
In vitro assembled 266/297 - 391 tau filaments with CuCl2 (12a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (2.83 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QL3
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BU of 7ql3 by Molmil
in vitro assembled 266/297 - 391 tau filaments with NaCl (8b)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QJV
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BU of 7qjv by Molmil
In vitro assembled tau filaments into Quadruple Helical Filaments type 1 (2c)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKL
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BU of 7qkl by Molmil
In vitro assembled 266/297 - 391 tau filaments with ZnCl2 (11a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.07 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QK1
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BU of 7qk1 by Molmil
In vitro assembled 297-394 tau filaments in PBS (35d)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QL0
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BU of 7ql0 by Molmil
In vitro assembled 266/297 - 391 tau filaments with MgSO4 and NaCl (15c)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKM
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BU of 7qkm by Molmil
In vitro assembled 266-391 S356D tau filaments with NaCl (45a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKK
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BU of 7qkk by Molmil
In vitro assembled 258-391 tau filaments with phosphoglycerate, 700 rpm (39a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QL1
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BU of 7ql1 by Molmil
In vitro assembled 266-391 tau filaments in PBS (23a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-19
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QK5
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BU of 7qk5 by Molmil
In vitro assembled 266/297 - 391 tau filaments with KCl (10a)
Descriptor: CHLORIDE ION, Microtubule-associated protein tau, POTASSIUM ION
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (1.92 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022
7QKI
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BU of 7qki by Molmil
In vitro assembled 297-408 S396D S400D T403D S404D tau filaments (42a)
Descriptor: Microtubule-associated protein tau
Authors:Lovestam, S, Scheres, S.H.W.
Deposit date:2021-12-17
Release date:2022-02-16
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Assembly of recombinant tau into filaments identical to those of Alzheimer's disease and chronic traumatic encephalopathy.
Elife, 11, 2022

226707

數據於2024-10-30公開中

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