3D9V
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1XAS
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![BU of 1xas by Molmil](/molmil-images/mine/1xas) | CRYSTAL STRUCTURE, AT 2.6 ANGSTROMS RESOLUTION, OF THE STREPTOMYCES LIVIDANS XYLANASE A, A MEMBER OF THE F FAMILY OF BETA-1,4-D-GLYCANSES | Descriptor: | 1,4-BETA-D-XYLAN XYLANOHYDROLASE | Authors: | Derewenda, U, Derewenda, Z.S. | Deposit date: | 1994-05-31 | Release date: | 1995-05-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure, at 2.6-A resolution, of the Streptomyces lividans xylanase A, a member of the F family of beta-1,4-D-glycanases. J.Biol.Chem., 269, 1994
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1BWQ
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![BU of 1bwq by Molmil](/molmil-images/mine/1bwq) | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | Descriptor: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | Authors: | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | Deposit date: | 1998-09-27 | Release date: | 1999-05-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase Protein Eng., 12, 1999
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1BWP
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![BU of 1bwp by Molmil](/molmil-images/mine/1bwp) | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | Descriptor: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | Authors: | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | Deposit date: | 1998-09-27 | Release date: | 1999-05-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase Protein Eng., 12, 1999
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1BWR
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![BU of 1bwr by Molmil](/molmil-images/mine/1bwr) | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | Descriptor: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | Authors: | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | Deposit date: | 1998-09-27 | Release date: | 1999-05-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase Protein Eng., 12, 1999
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1JFR
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1ES9
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![BU of 1es9 by Molmil](/molmil-images/mine/1es9) | X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH) | Descriptor: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB GAMMA SUBUNIT | Authors: | McMullen, T.W.P, Li, J, Sheffield, P.J, Aoki, J, Martin, T.W, Arai, H, Inoue, K, Derewenda, Z.S. | Deposit date: | 2000-04-07 | Release date: | 2000-05-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib). Protein Eng., 13, 2000
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1E0W
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![BU of 1e0w by Molmil](/molmil-images/mine/1e0w) | Xylanase 10A from Sreptomyces lividans. native structure at 1.2 angstrom resolution | Descriptor: | ENDO-1,4-BETA-XYLANASE A | Authors: | Ducros, V, Charnock, S.J, Derewenda, U, Derewenda, Z.S, Dauter, Z, Dupont, C, Shareck, F, Morosoli, R, Kluepfel, D, Davies, G.J. | Deposit date: | 2000-04-10 | Release date: | 2001-04-05 | Last modified: | 2014-02-05 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A J.Biol.Chem., 275, 2000
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1E0X
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![BU of 1e0x by Molmil](/molmil-images/mine/1e0x) | XYLANASE 10A FROM SREPTOMYCES LIVIDANS. XYLOBIOSYL-ENZYME INTERMEDIATE AT 1.65 A | Descriptor: | ENDO-1,4-BETA-XYLANASE A, GLYCEROL, beta-D-xylopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-xylopyranose | Authors: | Ducros, V, Charnock, S.J, Derewenda, U, Derewenda, Z.S, Dauter, Z, Dupont, C, Shareck, F, Morosoli, R, Kluepfel, D, Davies, G.J. | Deposit date: | 2000-04-10 | Release date: | 2001-04-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A J.Biol.Chem., 275, 2000
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1E0V
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![BU of 1e0v by Molmil](/molmil-images/mine/1e0v) | Xylanase 10A from Sreptomyces lividans. cellobiosyl-enzyme intermediate at 1.7 A | Descriptor: | ENDO-1,4-BETA-XYLANASE A, beta-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-glucopyranose | Authors: | Ducros, V, Charnock, S.J, Derewenda, U, Derewenda, Z.S, Dauter, Z, Dupont, C, Shareck, F, Morosoli, R, Kluepfel, D, Davies, G.J. | Deposit date: | 2000-04-10 | Release date: | 2001-04-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Substrate Specificity in Glycoside Hydrolase Family 10. Structural and Kinetic Analysis of the Streptomyces Lividans Xylanase 10A J.Biol.Chem., 275, 2000
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3DT9
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![BU of 3dt9 by Molmil](/molmil-images/mine/3dt9) | Crystal Structure of Bovin Brain Platelet Activating Factor Acetylhydrolase Covalently Inhibited by Soman | Descriptor: | (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE, Brain Platelet-activating factor acetylhydrolase IB subunit alpha | Authors: | Epstein, T.M, Samanta, U, Bahnson, B.J. | Deposit date: | 2008-07-14 | Release date: | 2009-05-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin. Biochemistry, 48, 2009
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3DT8
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3DT6
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4YTF
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![BU of 4ytf by Molmil](/molmil-images/mine/4ytf) | Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Diseases | Descriptor: | N~2~-[2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-N-(2,2,2-trifluoroethyl)-L-alaninamide, Tyrosine-protein kinase JAK2 | Authors: | Farmer, L, Ledeboer, M.W, Zuccola, H.J. | Deposit date: | 2015-03-17 | Release date: | 2015-08-12 | Last modified: | 2015-10-07 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases. J.Med.Chem., 58, 2015
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4YTI
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4YTC
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4YTH
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1C8U
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2JRT
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![BU of 2jrt by Molmil](/molmil-images/mine/2jrt) | NMR solution structure of the protein coded by gene RHOS4_12090 of Rhodobacter sphaeroides. Northeast Structural Genomics target RhR5 | Descriptor: | Uncharacterized protein | Authors: | Wang, L, Chen, C, Nwosu, C, Cunningham, K, Owens, L, Ma, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-06-28 | Release date: | 2007-08-21 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the protein coded by gene RHOS4_12090 of Rhodobacter sphaeroides. To be Published
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3KA7
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![BU of 3ka7 by Molmil](/molmil-images/mine/3ka7) | Crystal Structure of an oxidoreductase from Methanosarcina mazei. Northeast Structural Genomics Consortium target id MaR208 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Oxidoreductase | Authors: | Seetharaman, J, Su, M, Wang, D, Janjua, H, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-10-18 | Release date: | 2009-11-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of an oxidoreductase from Methanosarcina mazei To be Published
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2QS9
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![BU of 2qs9 by Molmil](/molmil-images/mine/2qs9) | Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978 | Descriptor: | Retinoblastoma-binding protein 9 | Authors: | Vorobiev, S.M, Su, M, Seetharaman, J, Kuzin, A, Chen, C.X, Cunningham, K, Owens, L, Maglaqui, M, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-07-30 | Release date: | 2007-08-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Crystal structure of human retinoblastoma binding protein 9. Proteins, 74, 2008
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2ESM
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![BU of 2esm by Molmil](/molmil-images/mine/2esm) | Crystal Structure of ROCK 1 bound to fasudil | Descriptor: | 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, Rho-associated protein kinase 1 | Authors: | Jacobs, M. | Deposit date: | 2005-10-26 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
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2ETK
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![BU of 2etk by Molmil](/molmil-images/mine/2etk) | Crystal Structure of ROCK 1 bound to hydroxyfasudil | Descriptor: | 1-(1-HYDROXY-5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, Rho-associated protein kinase 1 | Authors: | Jacobs, M. | Deposit date: | 2005-10-27 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
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2ETR
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![BU of 2etr by Molmil](/molmil-images/mine/2etr) | Crystal Structure of ROCK I bound to Y-27632 | Descriptor: | (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, Rho-associated protein kinase 1 | Authors: | Jacobs, M. | Deposit date: | 2005-10-27 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
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2ERZ
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![BU of 2erz by Molmil](/molmil-images/mine/2erz) | Crystal Structure of c-AMP Dependent Kinase (PKA) bound to hydroxyfasudil | Descriptor: | 1-(1-HYDROXY-5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE, cAMP-dependent protein kinase inhibitor, alpha form, ... | Authors: | Jacobs, M. | Deposit date: | 2005-10-25 | Release date: | 2005-11-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity. J.Biol.Chem., 281, 2006
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