3DT8

Crystal Structure of Bovin Brain Platelet Activating Factor Acetylhydrolase Covalently Inhibited by Sarin

Summary for 3DT8

Entry DOI	10.2210/pdb3dt8/pdb
Related	1WAB 3DT6 3DT9
Descriptor	Brain Platelet-activating factor acetylhydrolase IB subunit alpha (2 entities in total)
Functional Keywords	platelet activating factor acetylhydrolase, paf-ah ib, alpha-1 subunit, lis1, group viii phospholipase a2, 26 kda, sarin, cytoplasm, hydrolase, lipid degradation, platelet factor
Biological source	Bos taurus (bovine,cow,domestic cattle,domestic cow)
Total number of polymer chains	1
Total formula weight	26007.38
Authors	Epstein, T.M.,Samanta, U.,Bahnson, B.J. (deposition date: 2008-07-14, release date: 2009-05-12, Last modification date: 2023-08-30)
Primary citation	Epstein, T.M.,Samanta, U.,Kirby, S.D.,Cerasoli, D.M.,Bahnson, B.J. Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin. Biochemistry, 48:3425-3435, 2009 Cited by PubMed: 19271773 DOI: 10.1021/bi8023527 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation