1N7D
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![BU of 1n7d by Molmil](/molmil-images/mine/1n7d) | Extracellular domain of the LDL receptor | Descriptor: | 12-TUNGSTOPHOSPHATE, CALCIUM ION, Low-density lipoprotein receptor, ... | Authors: | Rudenko, G, Henry, L, Henderson, K, Ichtchenko, K, Brown, M.S, Goldstein, J.L, Deisenhofer, J. | Deposit date: | 2002-11-13 | Release date: | 2003-01-21 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structure of the LDL receptor extracellular domain at endosomal pH Science, 298, 2002
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5LKN
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![BU of 5lkn by Molmil](/molmil-images/mine/5lkn) | NMR solution structure of human FNIII domain 2 of NCAM | Descriptor: | Neural cell adhesion molecule 1 | Authors: | Slapsak, U, Salzano, G, Amin, L, Abskharon, R.N.N, Ilc, G, Zupancic, B, Biljan, I, Plavec, J, Giachin, G, Legname, G. | Deposit date: | 2016-07-22 | Release date: | 2016-09-14 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain. J.Biol.Chem., 291, 2016
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5B00
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![BU of 5b00 by Molmil](/molmil-images/mine/5b00) | Structure of the prenyltransferase MoeN5 in complex with geranyl pyrophosphate | Descriptor: | GERANYL DIPHOSPHATE, MoeN5 | Authors: | Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2015-10-27 | Release date: | 2016-03-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5. Angew.Chem.Int.Ed.Engl., 55, 2016
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5B0L
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![BU of 5b0l by Molmil](/molmil-images/mine/5b0l) | Structure of MoeN5-Sso7d fusion protein in complex with beta-nonyl glucoside | Descriptor: | MoeN5,DNA-binding protein 7d, nonyl beta-D-glucopyranoside | Authors: | Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O. | Deposit date: | 2015-11-02 | Release date: | 2016-03-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5. Angew.Chem.Int.Ed.Engl., 55, 2016
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5WNO
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![BU of 5wno by Molmil](/molmil-images/mine/5wno) | Crystal structure of C. elegans LET-23 kinase domain complexed with AMP-PNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Receptor tyrosine-protein kinase let-23 | Authors: | Liu, L, Thaker, T.M, Jura, N. | Deposit date: | 2017-08-01 | Release date: | 2018-01-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.386 Å) | Cite: | Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23. Structure, 26, 2018
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1MIH
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![BU of 1mih by Molmil](/molmil-images/mine/1mih) | A ROLE FOR CHEY GLU 89 IN CHEZ-MEDIATED DEPHOSPHORYLATION OF THE E. COLI CHEMOTAXIS RESPONSE REGULATOR CHEY | Descriptor: | BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein cheY, MANGANESE (II) ION, ... | Authors: | Silversmith, R.E, Guanga, G.P, Betts, L, Chu, C, Zhao, R, Bourret, R.B. | Deposit date: | 2002-08-23 | Release date: | 2003-04-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | CheZ-mediated dephosphorylation of the Escherichia coli chemotaxis response regulator CheY: role for CheY glutamate 89. J.Bacteriol., 185, 2003
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5WZZ
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![BU of 5wzz by Molmil](/molmil-images/mine/5wzz) | The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation | Descriptor: | Axin-1, E3 ubiquitin-protein ligase SIAH1, ZINC ION | Authors: | Ji, L, Jiang, B, Jiang, X, Charlat, O, Chen, A, Mickanin, C, Bauer, A, Xu, W, Yan, X.-X, Cong, F. | Deposit date: | 2017-01-19 | Release date: | 2017-08-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.103 Å) | Cite: | The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation Genes Dev., 31, 2017
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1XQZ
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![BU of 1xqz by Molmil](/molmil-images/mine/1xqz) | Crystal Structure of hPim-1 kinase at 2.1 A resolution | Descriptor: | Proto-oncogene serine/threonine-protein kinase Pim-1 | Authors: | Qian, K.C, Wang, L, Hickey, E.R, Studts, J, Barringer, K, Peng, C, Kronkaitis, A, Li, J, White, A, Mische, S, Farmer, B. | Deposit date: | 2004-10-13 | Release date: | 2004-11-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis of Constitutive Activity and a Unique Nucleotide Binding Mode of Human Pim-1 Kinase. J.Biol.Chem., 280, 2005
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5WTE
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![BU of 5wte by Molmil](/molmil-images/mine/5wte) | Cryo-EM structure for Hepatitis A virus full particle | Descriptor: | VP1, VP2, VP3 | Authors: | Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. | Deposit date: | 2016-12-11 | Release date: | 2017-01-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1MNY
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![BU of 1mny by Molmil](/molmil-images/mine/1mny) | Dimethyl propionate ester heme-containing cytochrome b5 | Descriptor: | DIMETHYL PROPIONATE ESTER HEME, cytochrome b5 | Authors: | Banci, L, Bertini, I, Branchini, B.R, Hajieva, P, Spyroulias, G.A, Turano, P. | Deposit date: | 2002-09-06 | Release date: | 2002-11-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Dimethyl propionate ester heme-containing cytochrome b5: structure and stability. J.BIOL.INORG.CHEM., 6, 2001
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1XSQ
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![BU of 1xsq by Molmil](/molmil-images/mine/1xsq) | Crystal structure of ureidoglycolate hydrolase from E.coli. Northeast Structural Genomics Consortium target ET81. | Descriptor: | Ureidoglycolate hydrolase | Authors: | Kuzin, A.P, Vorobiev, S.M, Abashidze, M, Acton, T.B, Ma, L.-C, Xiao, R, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-10-19 | Release date: | 2004-11-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of ureidoglycolate hydrolase from E.coli. Northeast Structural Genomics Consortium target ET81. To be Published
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5MJ5
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![BU of 5mj5 by Molmil](/molmil-images/mine/5mj5) | Crystal structure of the Retinoid X Receptor alpha in complex with synthetichonokiol derivative 3 and a fragment of the TIF2 co-activator. | Descriptor: | (~{E})-3-[4-oxidanyl-3-[3-(phenylmethyl)phenyl]phenyl]prop-2-enoic acid, LYS-HIS-LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN-ASP-SER, Retinoic acid receptor RXR-alpha | Authors: | Andrei, S.A, Brunsveld, L, Scheepstra, M, Ottmann, C. | Deposit date: | 2016-11-30 | Release date: | 2017-11-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization. ACS Chem Neurosci, 8, 2017
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5B03
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![BU of 5b03 by Molmil](/molmil-images/mine/5b03) | Structure of MoeN5-Sso7d fusion protein in complex with geranyl pyrophosphate | Descriptor: | GERANYL DIPHOSPHATE, MoeN5,DNA-binding protein 7d | Authors: | Ko, T.-P, Zhang, L, Chen, C.-C, Guo, R.-T, Oldfield, E.O. | Deposit date: | 2015-10-27 | Release date: | 2016-03-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5. Angew.Chem.Int.Ed.Engl., 55, 2016
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5MBL
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5B6L
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![BU of 5b6l by Molmil](/molmil-images/mine/5b6l) | Structure of Deg protease HhoA from Synechocystis sp. PCC 6803 | Descriptor: | Putative serine protease HhoA, SODIUM ION, UNK-UNK-UNK-UNK-TRP, ... | Authors: | Dong, W, Wang, J, Liu, L. | Deposit date: | 2016-05-30 | Release date: | 2016-09-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Crystal structure of the zinc-bound HhoA protease from Synechocystis sp. PCC 6803 Febs Lett., 590, 2016
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1XUW
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![BU of 1xuw by Molmil](/molmil-images/mine/1xuw) | Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogs | Descriptor: | DNA (5'-D(*GP*CP*GP*TP*AP*(NMT)P*AP*CP*GP*C)-3') | Authors: | Pattanayek, R, Sethaphong, L, Pan, C, Prhavc, M, Prakash, T.P, Manoharan, M, Egli, M. | Deposit date: | 2004-10-26 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues. J.Am.Chem.Soc., 126, 2004
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5WWW
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![BU of 5www by Molmil](/molmil-images/mine/5www) | Crystal structure of the KH1 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C complex with RNA | Descriptor: | RNA (5'-R(*GP*UP*UP*UP*AP*G)-3'), RNA-binding E3 ubiquitin-protein ligase MEX3C | Authors: | Yang, L, Wang, C, Li, F, Gong, Q. | Deposit date: | 2017-01-05 | Release date: | 2017-08-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity J. Biol. Chem., 292, 2017
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5WWZ
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![BU of 5wwz by Molmil](/molmil-images/mine/5wwz) | Crystal structure of the KH2 domain of human RNA-binding E3 ubiquitin-protein ligase MEX-3C | Descriptor: | RNA-binding E3 ubiquitin-protein ligase MEX3C, SULFATE ION | Authors: | Yang, L, Wang, C, Li, F, Gong, Q. | Deposit date: | 2017-01-05 | Release date: | 2017-08-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The human RNA-binding protein and E3 ligase MEX-3C binds the MEX-3-recognition element (MRE) motif with high affinity J. Biol. Chem., 292, 2017
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1XWG
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![BU of 1xwg by Molmil](/molmil-images/mine/1xwg) | Human GST A1-1 T68E mutant | Descriptor: | Glutathione S-transferase A1 | Authors: | Grahn, E, Jakobsson, E, Gustafsson, A, Novotny, M, Grehn, L, Olin, B, Madsen, D, Wahlberg, M, Mannervik, B, Kleywegt, G.J. | Deposit date: | 2004-11-01 | Release date: | 2005-11-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix. Acta Crystallogr.,Sect.D, 62, 2006
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5WXF
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![BU of 5wxf by Molmil](/molmil-images/mine/5wxf) | Crystal structure of uPA in complex with upain-2-2 | Descriptor: | SULFATE ION, Urokinase-type plasminogen activator chain B, upain-2-2 peptide | Authors: | Jiang, L, Huang, M. | Deposit date: | 2017-01-07 | Release date: | 2018-07-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. Biochim. Biophys. Acta, 1862, 2018
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5MEL
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![BU of 5mel by Molmil](/molmil-images/mine/5mel) | Structure of an E333Q variant of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with Glc-alpha-1,3-(3R,4R,5R)-5-(hydroxymethyl)cyclohex-1,2-ene-3,4-diol | Descriptor: | (1~{R},2~{R},6~{R})-6-(hydroxymethyl)cyclohex-3-ene-1,2-diol, ACETATE ION, Glycosyl hydrolase family 71, ... | Authors: | Petricevic, M, Sobala, L.F, Fernandes, P.Z, Raich, L, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J. | Deposit date: | 2016-11-15 | Release date: | 2017-01-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-alpha-1,2-Mannanase. J. Am. Chem. Soc., 139, 2017
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5WXR
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1MP9
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![BU of 1mp9 by Molmil](/molmil-images/mine/1mp9) | TBP from a mesothermophilic archaeon, Sulfolobus acidocaldarius | Descriptor: | TATA-binding protein | Authors: | Koike, H, Kawashima-Ohya, Y, Yamasaki, T, Clowney, L, Katsuya, Y, Suzuki, M. | Deposit date: | 2002-09-12 | Release date: | 2003-11-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Origins of Protein Stability Revealed by Comparing Crystal Structures of TATA Binding Proteins. Structure, 12, 2004
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5CHE
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1XY6
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![BU of 1xy6 by Molmil](/molmil-images/mine/1xy6) | NMR strcutre of sst1-selective somatostatin (SRIF) analog 1 | Descriptor: | SST1-selective somatosatin analog | Authors: | Grace, C.R.R, Durrer, L, Koerber, S.C, Erchegyi, J, Reubi, J.C, Rivier, J.E, Riek, R. | Deposit date: | 2004-11-09 | Release date: | 2005-02-15 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Somatostatin receptor 1 selective analogues: 4. Three-dimensional consensus structure by NMR J.Med.Chem., 48, 2005
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