5WNO

Crystal structure of C. elegans LET-23 kinase domain complexed with AMP-PNP

Summary for 5WNO

Entry DOI	10.2210/pdb5wno/pdb
Descriptor	Receptor tyrosine-protein kinase let-23, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	receptor tyrosine-protein kinase, dimerization, inactive conformation, cell signaling, let-23, c. elegans, transferase
Biological source	Caenorhabditis elegans
Total number of polymer chains	1
Total formula weight	38480.11
Authors	Liu, L.,Thaker, T.M.,Jura, N. (deposition date: 2017-08-01, release date: 2018-01-31, Last modification date: 2023-10-04)
Primary citation	Liu, L.,Thaker, T.M.,Freed, D.M.,Frazier, N.,Malhotra, K.,Lemmon, M.A.,Jura, N. Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23. Structure, 26:270-281.e4, 2018 Cited by PubMed: 29358026 DOI: 10.1016/j.str.2017.12.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.386 Å)

Structure validation