6LMV
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![BU of 6lmv by Molmil](/molmil-images/mine/6lmv) | Cryo-EM structure of the C. elegans CLHM-1 | Descriptor: | Calcium homeostasis modulator protein | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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2RNO
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6LMU
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![BU of 6lmu by Molmil](/molmil-images/mine/6lmu) | Cryo-EM structure of the human CALHM2 | Descriptor: | Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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6LMX
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![BU of 6lmx by Molmil](/molmil-images/mine/6lmx) | Cryo-EM structure of the CALHM chimeric construct (9-mer) | Descriptor: | Calcium homeostasis modulator 1,Calcium homeostasis modulator protein 2 | Authors: | Demura, K, Kusakizako, T, Shihoya, W, Hiraizumi, M, Shimada, H, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-12-26 | Release date: | 2020-07-29 | Last modified: | 2020-09-09 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structures of calcium homeostasis modulator channels in diverse oligomeric assemblies. Sci Adv, 6, 2020
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7Y9Y
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![BU of 7y9y by Molmil](/molmil-images/mine/7y9y) | Structure of the Cas7-11-Csx29-guide RNA-target RNA (no PFS) complex | Descriptor: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, RNA (27-MER), ... | Authors: | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | Deposit date: | 2022-06-26 | Release date: | 2022-11-09 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
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7Y9X
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![BU of 7y9x by Molmil](/molmil-images/mine/7y9x) | Structure of the Cas7-11-Csx29-guide RNA complex | Descriptor: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, ZINC ION, ... | Authors: | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | Deposit date: | 2022-06-26 | Release date: | 2022-11-09 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.49 Å) | Cite: | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
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6MCR
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![BU of 6mcr by Molmil](/molmil-images/mine/6mcr) | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-001 | Descriptor: | (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3-fluorophenyl)-3-hydroxybutan-2-yl]carbamate, 1,2-ETHANEDIOL, Protease | Authors: | Bulut, H, Hayashi, H, Hattori, S.I, Aoki, M, Das, D, Ghosh, A.K, Mitsuya, H. | Deposit date: | 2018-09-02 | Release date: | 2019-04-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Halogen Bond Interactions of Novel HIV-1 Protease Inhibitors (PI) (GRL-001-15 and GRL-003-15) with the Flap of Protease Are Critical for Their Potent Activity against Wild-Type HIV-1 and Multi-PI-Resistant Variants. Antimicrob.Agents Chemother., 63, 2019
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1GDV
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![BU of 1gdv by Molmil](/molmil-images/mine/1gdv) | CRYSTAL STRUCTURE OF CYTOCHROME C6 FROM RED ALGA PORPHYRA YEZOENSIS AT 1.57 A RESOLUTION | Descriptor: | CYTOCHROME C6, HEME C | Authors: | Yamada, S, Park, S.-Y, Shimizu, H, Shiro, Y, Oku, T. | Deposit date: | 2000-10-06 | Release date: | 2001-04-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Structure of cytochrome c6 from the red alga Porphyra yezoensis at 1. 57 A resolution. Acta Crystallogr.,Sect.D, 56, 2000
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7FCI
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![BU of 7fci by Molmil](/molmil-images/mine/7fci) | human NTCP in complex with YN69083 Fab | Descriptor: | Fab Heavy chain, Fab Light chain, Sodium/bile acid cotransporter | Authors: | Park, J.H, Iwamoto, M, Yun, J.H, Uchikubo-Kamo, T, Son, D, Jin, Z, Yoshida, H, Ohki, M, Ishimoto, N, Mizutani, K, Oshima, M, Muramatsu, M, Wakita, T, Shirouzu, M, Liu, K, Uemura, T, Nomura, N, Iwata, S, Watashi, K, Tame, J.R.H, Nishizawa, T, Lee, W, Park, S.Y. | Deposit date: | 2021-07-14 | Release date: | 2022-05-25 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insights into the HBV receptor and bile acid transporter NTCP. Nature, 606, 2022
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1MK8
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![BU of 1mk8 by Molmil](/molmil-images/mine/1mk8) | Crystal Structure of a Mutant Cytochrome c Peroxidase showing a Novel Trp-Tyr Covalent Cross-link | Descriptor: | Cytochrome c Peroxidase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Bhaskar, B, Immoos, C.E, Shimizu, H, Farmer, P.J, Poulos, T.L. | Deposit date: | 2002-08-28 | Release date: | 2003-04-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | A Novel Heme and Peroxide-Dependent Tryptophan-Tyrosine Cross-Link in a Mutant of Cytochrome c Peroxidase J.Mol.Biol., 328, 2003
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1MKQ
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![BU of 1mkq by Molmil](/molmil-images/mine/1mkq) | Crystal Structure of the Mutant Variant of Cytochrome c Peroxidase in the 'Open' Uncross-linked form | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cytochrome c Peroxidase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Bhaskar, B, Immoos, C.E, Shimizu, H, Farmer, P.J, Poulos, T.L. | Deposit date: | 2002-08-29 | Release date: | 2003-04-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | A Novel Heme and Peroxide-Dependent Tryptophan-Tyrosine Cross-Link in a Mutant of Cytochrome c Peroxidase J.Mol.Biol., 328, 2003
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1D8L
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![BU of 1d8l by Molmil](/molmil-images/mine/1d8l) | E. COLI HOLLIDAY JUNCTION BINDING PROTEIN RUVA NH2 REGION LACKING DOMAIN III | Descriptor: | PROTEIN (HOLLIDAY JUNCTION DNA HELICASE RUVA) | Authors: | Nishino, T, Iwasaki, H, Kataoka, M, Ariyoshi, M, Fujita, T, Shinagawa, H, Morikawa, K. | Deposit date: | 1999-10-25 | Release date: | 2000-05-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Modulation of RuvB function by the mobile domain III of the Holliday junction recognition protein RuvA. J.Mol.Biol., 298, 2000
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7Y8P
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![BU of 7y8p by Molmil](/molmil-images/mine/7y8p) | Crystal structure of 4'-selenoRNA duplex | Descriptor: | COBALT HEXAMMINE(III), RNA (5'-R(*GP*GP*AP*(IKS)P*(ILK)P*(IKS)P*GP*AP*GP*UP*CP*C)-3') | Authors: | Kondo, J, Minakawa, N, Ohta, M, Takahashi, H, Tarashima, N. | Deposit date: | 2022-06-24 | Release date: | 2023-05-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Synthesis and properties of fully-modified 4'-selenoRNA, an endonuclease-resistant RNA analog. Bioorg.Med.Chem., 76, 2022
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1C7Y
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![BU of 1c7y by Molmil](/molmil-images/mine/1c7y) | E.COLI RUVA-HOLLIDAY JUNCTION COMPLEX | Descriptor: | DNA (5'-D(P*DAP*DAP*DGP*DTP*DTP*DGP*DGP*DGP*DAP*DTP*DTP*DGP*DT)-3'), DNA (5'-D(P*DCP*DAP*DAP*DTP*DCP*DCP*DCP*DAP*DAP*DCP*DTP*DT)-3'), DNA (5'-D(P*DCP*DGP*DAP*DAP*DTP*DGP*DTP*DGP*DTP*DGP*DTP*DCP*DT)-3'), ... | Authors: | Ariyoshi, M, Nishino, T, Iwasaki, H, Shinagawa, H, Morikawa, K. | Deposit date: | 2000-04-03 | Release date: | 2000-07-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of the holliday junction DNA in complex with a single RuvA tetramer. Proc.Natl.Acad.Sci.USA, 97, 2000
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6L9C
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![BU of 6l9c by Molmil](/molmil-images/mine/6l9c) | Neutron structure of copper amine oxidase from Arthrobacter glibiformis at pD 7.4 | Descriptor: | COPPER (II) ION, Phenylethylamine oxidase, SODIUM ION | Authors: | Murakawa, T, Kurihara, K, Shoji, M, Shibazaki, C, Sunami, T, Tamada, T, Yano, N, Yamada, T, Kusaka, K, Suzuki, M, Shigeta, Y, Kuroki, R, Hayashi, H, Yano, Y, Tanizawa, K, Adachi, M, Okajima, T. | Deposit date: | 2019-11-08 | Release date: | 2020-04-29 | Last modified: | 2023-11-22 | Method: | NEUTRON DIFFRACTION (1.14 Å), X-RAY DIFFRACTION | Cite: | Neutron crystallography of copper amine oxidase reveals keto/enolate interconversion of the quinone cofactor and unusual proton sharing. Proc.Natl.Acad.Sci.USA, 117, 2020
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1ML2
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![BU of 1ml2 by Molmil](/molmil-images/mine/1ml2) | Crystal Structure of a Mutant Variant of Cytochrome c Peroxidase with Zn(II)-(20-oxo-Protoporphyrin IX) | Descriptor: | 20-OXO-PROTOPORPHYRIN IX CONTAINING ZN(II), Cytochrome c Peroxidase | Authors: | Bhaskar, B, Immoos, C.E, Shimizu, H, Farmer, P.J, Poulos, T.L. | Deposit date: | 2002-08-29 | Release date: | 2003-04-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | A Novel Heme and Peroxide-Dependent Tryptophan-Tyrosine Cross-Link in a Mutant of Cytochrome c Peroxidase J.Mol.Biol., 328, 2003
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1MKR
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![BU of 1mkr by Molmil](/molmil-images/mine/1mkr) | Crystal Structure of a Mutant Variant of Cytochrome c Peroxidase (Plate like crystals) | Descriptor: | Cytochrome c Peroxidase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Bhaskar, B, Immoos, C.E, Shimizu, H, Farmer, P.J, Poulos, T.L. | Deposit date: | 2002-08-29 | Release date: | 2003-04-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | A Novel Heme and Peroxide-Dependent Tryptophan-Tyrosine Cross-Link in a Mutant of Cytochrome c Peroxidase J.Mol.Biol., 328, 2003
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1I1K
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![BU of 1i1k by Molmil](/molmil-images/mine/1i1k) | CRYSTAL STRUCTURE OF ESCHELICHIA COLI BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE. | Descriptor: | BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Okada, K, Hirotsu, K, Hayashi, H, Kagamiyama, H. | Deposit date: | 2001-02-02 | Release date: | 2001-07-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme. Biochemistry, 40, 2001
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1I1L
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![BU of 1i1l by Molmil](/molmil-images/mine/1i1l) | CRYSTAL STRUCTURE OF ESCHELICHIA COLI BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE. | Descriptor: | 2-METHYLLEUCINE, BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Okada, K, Hirotsu, K, Hayashi, H, Kagamiyama, H. | Deposit date: | 2001-02-02 | Release date: | 2001-07-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme. Biochemistry, 40, 2001
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1I1M
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![BU of 1i1m by Molmil](/molmil-images/mine/1i1m) | CRYSTAL STRUCTURE OF ESCHERICHIA COLI BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE. | Descriptor: | 4-METHYL VALERIC ACID, BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE | Authors: | Okada, K, Hirotsu, K, Hayashi, H, Kagamiyama, H. | Deposit date: | 2001-02-02 | Release date: | 2001-07-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme. Biochemistry, 40, 2001
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1NEK
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![BU of 1nek by Molmil](/molmil-images/mine/1nek) | Complex II (Succinate Dehydrogenase) From E. Coli with ubiquinone bound | Descriptor: | CALCIUM ION, CARDIOLIPIN, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Yankovskaya, V, Horsefield, R, Tornroth, S, Luna-Chavez, C, Miyoshi, H, Leger, C, Byrne, B, Cecchini, G, Iwata, S. | Deposit date: | 2002-12-11 | Release date: | 2003-02-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Architecture of succinate dehydrogenase and
reactive oxygen species generation. Science, 299, 2003
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1NEN
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![BU of 1nen by Molmil](/molmil-images/mine/1nen) | Complex II (Succinate Dehydrogenase) From E. Coli with Dinitrophenol-17 inhibitor co-crystallized at the ubiquinone binding site | Descriptor: | 2-[1-METHYLHEXYL]-4,6-DINITROPHENOL, CALCIUM ION, CARDIOLIPIN, ... | Authors: | Yankovskaya, V, Horsefield, R, Tornroth, S, Luna-Chavez, C, Miyoshi, H, Leger, C, Byrne, B, Cecchini, G, Iwata, S. | Deposit date: | 2002-12-11 | Release date: | 2003-02-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Architecture of succinate dehydrogenase and
reactive oxygen species generation Science, 299, 2003
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1BMQ
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![BU of 1bmq by Molmil](/molmil-images/mine/1bmq) | CRYSTAL STRUCTURE OF THE COMPLEX OF INTERLEUKIN-1BETA CONVERTING ENZYME (ICE) WITH A PEPTIDE BASED INHIBITOR, (3S )-N-METHANESULFONYL-3-({1-[N-(2-NAPHTOYL)-L-VALYL]-L-PROLYL }AMINO)-4-OXOBUTANAMIDE | Descriptor: | (3S)-N-METHANESULFONYL-3-({1-[N-(2-NAPHTOYL)-L-VALYL]-L-PROLYL}AMINO)-4-OXOBUTANAMIDE, PROTEIN (INTERLEUKIN-1 BETA CONVERTASE) | Authors: | Okamoto, Y, Anan, H, Nakai, E, Morihira, K, Yonetoku, Y, Kurihara, H, Katayama, N, Sakashita, H, Terai, Y, Takeuchi, M, Shibanuma, T, Isomura, Y. | Deposit date: | 1998-07-24 | Release date: | 1998-07-29 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Peptide based interleukin-1 beta converting enzyme (ICE) inhibitors: synthesis, structure activity relationships and crystallographic study of the ICE-inhibitor complex. Chem.Pharm.Bull., 47, 1999
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1GIR
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![BU of 1gir by Molmil](/molmil-images/mine/1gir) | CRYSTAL STRUCTURE OF THE ENZYMATIC COMPONET OF IOTA-TOXIN FROM CLOSTRIDIUM PERFRINGENS WITH NADPH | Descriptor: | IOTA TOXIN COMPONENT IA, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Tsuge, H, Nagahama, M, Nishimura, H, Hisatsune, J, Sakaguchi, Y, Itogawa, Y, Katunuma, N, Sakurai, J. | Deposit date: | 2001-03-12 | Release date: | 2003-01-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure and Site-directed Mutagenesis of Enzymatic Components from Clostridium perfringens Iota-toxin J.MOL.BIOL., 325, 2003
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1FV2
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![BU of 1fv2 by Molmil](/molmil-images/mine/1fv2) | The Hc fragment of tetanus toxin complexed with an analogue of its ganglioside receptor GT1B | Descriptor: | ETHYL-TRIMETHYL-SILANE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-beta-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PHOSPHATE ION, ... | Authors: | Fotinou, C, Emsley, P, Black, I, Ando, H, Ishida, H, Kiso, M, Sinha, K.A, Fairweather, N.F, Isaacs, N.W. | Deposit date: | 2000-09-18 | Release date: | 2001-09-05 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin. J.Biol.Chem., 276, 2001
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