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7X2D
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BU of 7x2d by Molmil
Cryo-EM structure of the tavapadon-bound D1 dopamine receptor and mini-Gs complex
Descriptor: 1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxy-phenyl]pyrimidine-2,4-dione, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:Teng, X, Zheng, S.
Deposit date:2022-02-25
Release date:2022-06-15
Last modified:2022-10-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Ligand recognition and biased agonism of the D1 dopamine receptor.
Nat Commun, 13, 2022
7X2C
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BU of 7x2c by Molmil
Cryo-EM structure of the fenoldopam-bound D1 dopamine receptor and mini-Gs complex
Descriptor: (1R)-6-chloranyl-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, CHOLESTEROL, D(1A) dopamine receptor, ...
Authors:Teng, X, Zheng, S.
Deposit date:2022-02-25
Release date:2022-06-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Ligand recognition and biased agonism of the D1 dopamine receptor.
Nat Commun, 13, 2022
7F0T
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BU of 7f0t by Molmil
Cryo-EM structure of dopamine receptor 1 and mini-Gs complex with dopamine bound
Descriptor: D(1A) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Xiao, T, Zheng, S.
Deposit date:2021-06-07
Release date:2022-06-15
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into G protein activation by D1 dopamine receptor.
Sci Adv, 8, 2022
7F1Z
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BU of 7f1z by Molmil
Cryo-EM structure of the GDP-bound dopamine receptor 1 and mini-Gs complex without Nb35
Descriptor: D(1A) dopamine receptor, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Xiao, T, Zheng, S.
Deposit date:2021-06-10
Release date:2022-06-15
Last modified:2022-07-13
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Structural insights into G protein activation by D1 dopamine receptor.
Sci Adv, 8, 2022
7F23
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BU of 7f23 by Molmil
Cryo-EM structure of the GTP-bound dopamine receptor 1 and mini-Gs complex with Nb35
Descriptor: D(1A) dopamine receptor, GUANOSINE-5'-TRIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Xiao, T, Zheng, S.
Deposit date:2021-06-10
Release date:2022-06-15
Last modified:2022-07-13
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structural insights into G protein activation by D1 dopamine receptor.
Sci Adv, 8, 2022
7F1O
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BU of 7f1o by Molmil
Cryo-EM structure of the GDP-bound dopamine receptor 1 and mini-Gs complex with Nb35
Descriptor: D(1A) dopamine receptor, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Xiao, T, Zheng, S.
Deposit date:2021-06-09
Release date:2022-06-15
Last modified:2022-07-13
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural insights into G protein activation by D1 dopamine receptor.
Sci Adv, 8, 2022
7F24
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BU of 7f24 by Molmil
Cryo-EM structure of the GTP-bound dopamine receptor 1 and mini-Gs complex without Nb35
Descriptor: D(1A) dopamine receptor, GUANOSINE-5'-TRIPHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Xiao, T, Zheng, S.
Deposit date:2021-06-10
Release date:2022-06-15
Last modified:2022-07-13
Method:ELECTRON MICROSCOPY (4.16 Å)
Cite:Structural insights into G protein activation by D1 dopamine receptor.
Sci Adv, 8, 2022
7XJL
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BU of 7xjl by Molmil
Cryo-EM structure of the spexin-bound GALR2-miniGq complex
Descriptor: Galanin receptor type 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Jiang, W, Zheng, S.
Deposit date:2022-04-18
Release date:2022-06-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural insights into galanin receptor signaling.
Proc.Natl.Acad.Sci.USA, 119, 2022
7XJK
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BU of 7xjk by Molmil
Cryo-EM structure of the galanin-bound GALR2-miniGq complex
Descriptor: Galanin, Galanin receptor type 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Jiang, W, Zheng, S.
Deposit date:2022-04-18
Release date:2022-06-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into galanin receptor signaling.
Proc.Natl.Acad.Sci.USA, 119, 2022
7XJJ
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BU of 7xjj by Molmil
Cryo-EM structure of the galanin-bound GALR1-miniGo complex
Descriptor: G protein subunit alpha o1,Guanine nucleotide-binding protein G(o) subunit alpha, Galanin, Galanin receptor type 1, ...
Authors:Jiang, W, Zheng, S.
Deposit date:2022-04-18
Release date:2023-05-03
Last modified:2023-09-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into galanin receptor signaling.
Proc.Natl.Acad.Sci.USA, 119, 2022
2HV9
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BU of 2hv9 by Molmil
Encephalitozoon cuniculi mRNA Cap (Guanine-N7) Methyltransferase in complex with sinefungin
Descriptor: SINEFUNGIN, mRNA cap guanine-N7 methyltransferase
Authors:Lima, C.D.
Deposit date:2006-07-27
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mutational Analysis of Encephalitozoon cuniculi mRNA Cap (Guanine-N7) Methyltransferase, Structure of the Enzyme Bound to Sinefungin, and Evidence That Cap Methyltransferase Is the Target of Sinefungin's Antifungal Activity
J.Biol.Chem., 281, 2006
6IP0
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BU of 6ip0 by Molmil
Crystal structure of Arabidopsis thaliana JMJ13 catalytic domain in complex with AKG
Descriptor: 2-OXOGLUTARIC ACID, NICKEL (II) ION, SULFATE ION, ...
Authors:Hu, H, Du, J.
Deposit date:2018-11-01
Release date:2019-04-10
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor.
Nat Commun, 10, 2019
6IP4
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BU of 6ip4 by Molmil
Crystal structure of Arabidopsis thaliana JMJ13 catalytic domain in complex with NOG and an H3K27me3 peptide
Descriptor: Arabidopsis JMJ13, Histone H3.2, N-OXALYLGLYCINE, ...
Authors:Hu, H, Du, J.
Deposit date:2018-11-02
Release date:2019-04-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor.
Nat Commun, 10, 2019
2KHP
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BU of 2khp by Molmil
Solution structure of Glutaredoxin from Brucella melitensis
Descriptor: GLUTAREDOXIN
Authors:Zheng, S, Leeper, T, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-04-10
Release date:2009-05-05
Last modified:2020-02-26
Method:SOLUTION NMR
Cite:Comparative analysis of glutaredoxin domains from bacterial opportunistic pathogens.
Acta Crystallogr.,Sect.F, 67, 2011
3L0L
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BU of 3l0l by Molmil
Crystal structure of orphan nuclear receptor RORgamma in complex with natural ligand
Descriptor: 25-HYDROXYCHOLESTEROL, Nuclear receptor ROR-gamma, SCR2-2
Authors:Martynowski, D, Li, Y.
Deposit date:2009-12-10
Release date:2010-03-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma.
Mol.Endocrinol., 24, 2010
5WYK
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BU of 5wyk by Molmil
Cryo-EM structure of the 90S small subunit pre-ribosome (Mtr4-depleted, Enp1-TAP)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ...
Authors:Ye, K, Zhu, X, Sun, Q.
Deposit date:2017-01-13
Release date:2017-03-29
Last modified:2017-05-17
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
5WYJ
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BU of 5wyj by Molmil
Cryo-EM structure of the 90S small subunit pre-ribosome (Dhr1-depleted, Enp1-TAP, state 1)
Descriptor: 13 kDa ribonucleoprotein-associated protein, 18S ribosomal RNA, 40S ribosomal protein S1-A, ...
Authors:Ye, K, Zhu, X, Sun, Q.
Deposit date:2017-01-13
Release date:2017-03-29
Last modified:2019-10-09
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome.
Elife, 6, 2017
5WY3
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BU of 5wy3 by Molmil
Crystal structure of Chaetomium thermophilum Utp10 middle domain
Descriptor: Putative uncharacterized protein
Authors:Chen, R, Zhu, X, Ye, K.
Deposit date:2017-01-10
Release date:2017-06-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Molecular architecture of the 90S small subunit pre-ribosome
Elife, 6, 2017
7T86
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BU of 7t86 by Molmil
Crystal Structure of Fab CR5133 / Phospho-SD Peptide Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab CR5133 Heavy Chain, Antibody Fab CR5133 Light Chain, ...
Authors:Luo, J, Malia, T.J, Buckley, P.T.
Deposit date:2021-12-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Cell Host Microbe, 31, 2023
7T82
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BU of 7t82 by Molmil
Crystal Structure of LEUKOCIDIN E/CENTYRIN S26/FAB B438
Descriptor: Antibody Fab Heavy Chain, Antibody Fab Light Chain, Centyrin S26, ...
Authors:Luo, J, Malia, T.J, Buckley, P.T.
Deposit date:2021-12-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Cell Host Microbe, 31, 2023
7T87
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BU of 7t87 by Molmil
CRYSTAL STRUCTURE OF LEUKOCIDIN AB/CENTYRIN S17/FAB 214F COMPLEX
Descriptor: Antibody Fab B214 Heavy Chain, Antibody Fab B214 Light Chain, Centyrin S17, ...
Authors:Luo, J, Malia, T.J, Buckley, P.T.
Deposit date:2021-12-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Cell Host Microbe, 31, 2023
1Z3C
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BU of 1z3c by Molmil
Encephalitozooan cuniculi mRNA Cap (Guanine-N7) Methyltransferasein complexed with AzoAdoMet
Descriptor: S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE, mRNA CAPPING ENZYME
Authors:Hausmann, S, Zhang, S, Fabrega, C, Schneller, S.W, Lima, C.D, Shuman, S.
Deposit date:2005-03-11
Release date:2005-03-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis.
J.Biol.Chem., 280, 2005
5EIB
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BU of 5eib by Molmil
Crystal structure of CPAP PN2-3 C-terminal loop-helix in complex with DARPin-tubulin
Descriptor: Designed ankyrin repeat protein, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Li, H, Zheng, X.
Deposit date:2015-10-29
Release date:2016-10-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular basis for CPAP-tubulin interaction in controlling centriolar and ciliary length
Nat Commun, 7, 2016
7BTN
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BU of 7btn by Molmil
Crystal structure of human inorganic pyrophosphatase with metal ions
Descriptor: Inorganic pyrophosphatase, MAGNESIUM ION
Authors:Hu, F, Huang, Z, Li, L.
Deposit date:2020-04-02
Release date:2020-10-21
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.382 Å)
Cite:Structural and biochemical characterization of inorganic pyrophosphatase from Homo sapiens.
Biochem.Biophys.Res.Commun., 533, 2020
2Y78
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BU of 2y78 by Molmil
Crystal structure of BPSS1823, a Mip-like chaperone from Burkholderia pseudomallei
Descriptor: CHLORIDE ION, GLYCEROL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, ...
Authors:Norville, I.H, O'Shea, K, Sarkar-Tyson, M, Harmer, N.J.
Deposit date:2011-01-28
Release date:2011-05-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (0.91 Å)
Cite:The Structure of a Burkholderia Pseudomallei Immunophilin-Inhibitor Complex Reveals New Approaches to Antimicrobial Development
Biochem.J., 437, 2011

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數據於2024-06-12公開中

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