7F0T

Cryo-EM structure of dopamine receptor 1 and mini-Gs complex with dopamine bound

Summary for 7F0T

Entry DOI	10.2210/pdb7f0t/pdb
EMDB information	31404
Descriptor	D(1A) dopamine receptor, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
Functional Keywords	gpcr, dopamine receptor, mini-gs, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	5
Total formula weight	146086.18
Authors	Xiao, T.,Zheng, S. (deposition date: 2021-06-07, release date: 2022-06-15, Last modification date: 2022-12-28)
Primary citation	Teng, X.,Chen, S.,Wang, Q.,Chen, Z.,Wang, X.,Huang, N.,Zheng, S. Structural insights into G protein activation by D1 dopamine receptor. Sci Adv, 8:eabo4158-eabo4158, 2022 Cited by PubMed: 35687690 DOI: 10.1126/sciadv.abo4158 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation