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7F24

Cryo-EM structure of the GTP-bound dopamine receptor 1 and mini-Gs complex without Nb35

Summary for 7F24
Entry DOI10.2210/pdb7f24/pdb
EMDB information31427
DescriptorGuanine nucleotide-binding protein G(s) subunit alpha isoforms short,Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, D(1A) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
Functional Keywordsgpcr, dopamine receptor, mini-gs, membrane protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains4
Total formula weight129256.86
Authors
Xiao, T.,Zheng, S. (deposition date: 2021-06-10, release date: 2022-06-15, Last modification date: 2022-07-13)
Primary citationTeng, X.,Chen, S.,Wang, Q.,Chen, Z.,Wang, X.,Huang, N.,Zheng, S.
Structural insights into G protein activation by D1 dopamine receptor.
Sci Adv, 8:eabo4158-eabo4158, 2022
Cited by
PubMed: 35687690
DOI: 10.1126/sciadv.abo4158
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.16 Å)
Structure validation

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