1MWR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mwr by Molmil](/molmil-images/mine/1mwr) | |
1MWS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mws by Molmil](/molmil-images/mine/1mws) | |
1MWU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mwu by Molmil](/molmil-images/mine/1mwu) | Structure of methicillin acyl-Penicillin binding protein 2a from methicillin resistant Staphylococcus aureus strain 27r at 2.60 A resolution. | Descriptor: | (2R,4S)-2-[(1R)-1-{[(2,6-dimethoxyphenyl)carbonyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CADMIUM ION, CHLORIDE ION, ... | Authors: | Lim, D.C, Strynadka, N.C.J. | Deposit date: | 2002-10-01 | Release date: | 2002-11-06 | Last modified: | 2012-02-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the beta lactam resistance of PBP2a from methicillin-resistant Staphylococcus aureus. Nat.Struct.Biol., 9, 2002
|
|
1LNW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lnw by Molmil](/molmil-images/mine/1lnw) | |
1JTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jtg by Molmil](/molmil-images/mine/1jtg) | CRYSTAL STRUCTURE OF TEM-1 BETA-LACTAMASE / BETA-LACTAMASE INHIBITOR PROTEIN COMPLEX | Descriptor: | BETA-LACTAMASE INHIBITORY PROTEIN, BETA-LACTAMASE TEM, CALCIUM ION | Authors: | Strynadka, N.C.J, Jensen, S.E, Alzari, P.M, James, M.N. | Deposit date: | 2001-08-20 | Release date: | 2001-10-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Crystal structure and kinetic analysis of beta-lactamase inhibitor protein-II in complex with TEM-1 beta-lactamase. Nat.Struct.Biol., 8, 2001
|
|
3HJP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hjp by Molmil](/molmil-images/mine/3hjp) | |
4MNN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mnn by Molmil](/molmil-images/mine/4mnn) | |
1TL9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tl9 by Molmil](/molmil-images/mine/1tl9) | High resolution crystal structure of calpain I protease core in complex with leupeptin | Descriptor: | CALCIUM ION, Calpain 1, large [catalytic] subunit, ... | Authors: | Moldoveanu, T, Campbell, R.L, Cuerrier, D, Davies, P.L. | Deposit date: | 2004-06-09 | Release date: | 2004-11-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site J.Mol.Biol., 343, 2004
|
|
1TLO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1tlo by Molmil](/molmil-images/mine/1tlo) | High resolution crystal structure of calpain I protease core in complex with E64 | Descriptor: | CALCIUM ION, Calpain 1, large [catalytic] subunit, ... | Authors: | Moldoveanu, T, Campbell, R.L, Cuerrier, D, Davies, P.L. | Deposit date: | 2004-06-09 | Release date: | 2004-11-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structures of Calpain-E64 and -Leupeptin Inhibitor Complexes Reveal Mobile Loops Gating the Active Site J.Mol.Biol., 343, 2004
|
|
3C5L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c5l by Molmil](/molmil-images/mine/3c5l) | |
3FVH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fvh by Molmil](/molmil-images/mine/3fvh) | |
3RQ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rq7 by Molmil](/molmil-images/mine/3rq7) | Polo-like kinase 1 Polo box domain in complex with a C6H5(CH2)8-derivatized peptide inhibitor | Descriptor: | C6H5(CH2)8-derivatized peptide inhibitor, Serine/threonine-protein kinase PLK1 | Authors: | Liu, F, Park, J.-E, Qian, W.-J, Lim, D.C, Graber, M, Berg, T, Yaffe, M.B, Lee, K.S, Burke Jr, T.R. | Deposit date: | 2011-04-27 | Release date: | 2011-07-20 | Last modified: | 2012-12-12 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel. Nat.Chem.Biol., 7, 2011
|
|
3HIH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hih by Molmil](/molmil-images/mine/3hih) | |
3HIK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3hik by Molmil](/molmil-images/mine/3hik) | Structure of human Plk1-PBD in complex with PLHSpT | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Pentamer phosphopeptide, ... | Authors: | Wlodawer, A, Moulaei, T. | Deposit date: | 2009-05-20 | Release date: | 2009-06-09 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Nat.Struct.Mol.Biol., 16, 2009
|
|
3DF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3df0 by Molmil](/molmil-images/mine/3df0) | Calcium-dependent complex between m-calpain and calpastatin | Descriptor: | CALCIUM ION, Calpain small subunit 1, Calpain-2 catalytic subunit, ... | Authors: | Moldoveanu, T, Gehring, K, Green, D.R. | Deposit date: | 2008-06-11 | Release date: | 2008-11-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains. Nature, 456, 2008
|
|
4O6W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o6w by Molmil](/molmil-images/mine/4o6w) | Peptide-Based Inhibitors of Plk1 Polo-box Domain | Descriptor: | Peptide-Based inhibitor, Serine/threonine-protein kinase PLK1 | Authors: | Qian, W.-J, Park, J.-E, Lim, D.C, Park, S.-Y, Lee, K.-W, Yaffe, M.B, Lee, K.S, Burke, T.R. | Deposit date: | 2013-12-23 | Release date: | 2014-12-03 | Method: | X-RAY DIFFRACTION (1.448 Å) | Cite: | Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in hela cells. Biopolymers, 102, 2014
|
|
3WX6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wx6 by Molmil](/molmil-images/mine/3wx6) | |
5X3R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5x3r by Molmil](/molmil-images/mine/5x3r) | Crystal structure of the SmcR complexed with QStatin | Descriptor: | 1-(5-bromanylthiophen-2-yl)sulfonylpyrazole, LuxR family transcriptional regulator, SULFATE ION | Authors: | Jang, S.Y, Hwang, J, Kim, M.H. | Deposit date: | 2017-02-07 | Release date: | 2018-01-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | QStatin, a Selective Inhibitor of Quorum Sensing inVibrioSpecies MBio, 9, 2018
|
|
3CKP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ckp by Molmil](/molmil-images/mine/3ckp) | Crystal structure of BACE-1 in complex with inhibitor | Descriptor: | (4S)-N-[(1S,2R)-1-benzyl-3-{[3-(dimethylamino)benzyl]amino}-2-hydroxypropyl]-1-(3-methoxybenzyl)-2-oxoimidazolidine-4-carboxamide, Beta-secretase 1, CHLORIDE ION | Authors: | Min, K. | Deposit date: | 2008-03-16 | Release date: | 2008-06-03 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Synthesis, SAR, and X-ray structure of human BACE-1 inhibitors with cyclic urea derivatives Bioorg.Med.Chem.Lett., 18, 2008
|
|
3CKR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ckr by Molmil](/molmil-images/mine/3ckr) | Crystal structure of BACE-1 in complex with inhibitor | Descriptor: | (4S)-1,4-dibenzyl-N-[(1S,2R)-1-benzyl-3-{[3-(dimethylamino)benzyl]amino}-2-hydroxypropyl]-2-oxoimidazolidine-4-carboxamide, Beta-secretase 1 | Authors: | Min, K. | Deposit date: | 2008-03-16 | Release date: | 2008-06-03 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Synthesis, SAR, and X-ray structure of human BACE-1 inhibitors with cyclic urea derivatives Bioorg.Med.Chem.Lett., 18, 2008
|
|
6S7Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s7q by Molmil](/molmil-images/mine/6s7q) | |
6S7J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s7j by Molmil](/molmil-images/mine/6s7j) | |
4HAB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hab by Molmil](/molmil-images/mine/4hab) | Crystal structure of Plk1 Polo-box domain in complex with PL-49 | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, PHOSPHATE ION, PL-49, ... | Authors: | Lee, W.C, Song, J.H, Kim, H.Y. | Deposit date: | 2012-09-26 | Release date: | 2013-04-03 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1. Bioorg.Med.Chem., 21, 2013
|
|
4HY2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hy2 by Molmil](/molmil-images/mine/4hy2) | |
1Q16
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1q16 by Molmil](/molmil-images/mine/1q16) | Crystal structure of Nitrate Reductase A, NarGHI, from Escherichia coli | Descriptor: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, FE3-S4 CLUSTER, ... | Authors: | Bertero, M.G, Strynadka, N.C.J. | Deposit date: | 2003-07-18 | Release date: | 2003-10-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insights into the respiratory electron transfer pathway from the structure of nitrate reductase A Nat.Struct.Biol., 10, 2003
|
|