6OST
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![BU of 6ost by Molmil](/molmil-images/mine/6ost) | RF2 pre-accommodated state bound Release complex 70S at 24ms | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | Deposit date: | 2019-05-02 | Release date: | 2019-06-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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6OSQ
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![BU of 6osq by Molmil](/molmil-images/mine/6osq) | RF1 accommodated state bound Release complex 70S at long incubation time point | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. | Deposit date: | 2019-05-02 | Release date: | 2019-06-26 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
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5ZWS
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![BU of 5zws by Molmil](/molmil-images/mine/5zws) | |
1FYU
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![BU of 1fyu by Molmil](/molmil-images/mine/1fyu) | |
7AJR
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![BU of 7ajr by Molmil](/molmil-images/mine/7ajr) | Virtual screening approach leading to the identification of a novel and tractable series of Pseudomonas aeruginosa elastase inhibitors | Descriptor: | 2-[2-(1,3-benzothiazol-2-ylmethylcarbamoyl)-1,3-dihydroinden-2-yl]ethanoic acid, Keratinase KP2, SULFATE ION, ... | Authors: | Leiris, S, Davies, D.T, Sprinsky, N, Castandet, J, Behria, L, Bodnarchuk, M.S, Sutton, J.M, Mullins, T.M.G, Jones, M.W, Forrest, A.K, Pallin, T.D, Karunakar, P, Martha, S.K, Parusharamulu, B, Ramula, R, Kotha, V, Pottabathini, N, Pothukanuri, S, Lemonnier, M, Everett, M. | Deposit date: | 2020-09-29 | Release date: | 2021-02-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Virtual Screening Approach to Identifying a Novel and Tractable Series of Pseudomonas aeruginosa Elastase Inhibitors. Acs Med.Chem.Lett., 12, 2021
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1PJD
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![BU of 1pjd by Molmil](/molmil-images/mine/1pjd) | Structure and Topology of a Peptide Segment of the 6th Transmembrane Domain of the Saccharomyces cerevisiae alpha-Factor Receptor in Phospholipid Bilayers | Descriptor: | Pheromone alpha factor receptor | Authors: | Valentine, K.G, Liu, S.-F, Marassi, F.M, Veglia, G, Nevzorov, A.A, Opella, S.J, Ding, F.-X, Wang, S.-H, Arshava, B, Becker, J.M, Naider, F. | Deposit date: | 2003-06-02 | Release date: | 2003-09-16 | Last modified: | 2024-05-22 | Method: | SOLID-STATE NMR | Cite: | Structure and Topology of a Peptide Segment of the 6th Transmembrane Domain of the Saccharomyces cerevisiae alpha-Factor Receptor in Phospholipid Bilayers Biopolymers, 59, 2001
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6H77
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![BU of 6h77 by Molmil](/molmil-images/mine/6h77) | E1 enzyme for ubiquitin like protein activation in complex with UBL | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Soudah, N, Padala, P, Hassouna, F, Mashahreh, B, Lebedev, A.A, Isupov, M.N, Cohen-Kfir, E, Wiener, R. | Deposit date: | 2018-07-30 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation. J.Mol.Biol., 431, 2019
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6H78
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![BU of 6h78 by Molmil](/molmil-images/mine/6h78) | E1 enzyme for ubiquitin like protein activation. | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... | Authors: | Soudah, N, Padala, P, Hassouna, F, Mashahreh, B, Lebedev, A.A, Isupov, M.N, Cohen-Kfir, E, Wiener, R. | Deposit date: | 2018-07-30 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation. J.Mol.Biol., 431, 2019
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2F1F
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![BU of 2f1f by Molmil](/molmil-images/mine/2f1f) | Crystal structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from E. coli | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Acetolactate synthase isozyme III small subunit, MAGNESIUM ION, ... | Authors: | Kaplun, A, Vyazmensky, M, Barak, Z, Chipman, D.M, Shaanan, B. | Deposit date: | 2005-11-14 | Release date: | 2006-01-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of the Regulatory Subunit of Acetohydroxyacid Synthase Isozyme III from Escherichia coli. J.Mol.Biol., 357, 2006
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1BCG
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![BU of 1bcg by Molmil](/molmil-images/mine/1bcg) | SCORPION TOXIN BJXTR-IT | Descriptor: | TOXIN BJXTR-IT | Authors: | Oren, D, Froy, O, Amit, E, Kleinberger-Doron, N, Gurevitz, M, Shaanan, B. | Deposit date: | 1998-04-29 | Release date: | 1998-11-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | An excitatory scorpion toxin with a distinctive feature: an additional alpha helix at the C terminus and its implications for interaction with insect sodium channels. Structure, 6, 1998
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3HZS
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![BU of 3hzs by Molmil](/molmil-images/mine/3hzs) | S. aureus monofunctional glycosyltransferase (MtgA)in complex with moenomycin | Descriptor: | MOENOMYCIN, Monofunctional glycosyltransferase, PHOSPHATE ION | Authors: | Heaslet, H, Miller, A.A, Shaw, B, Mistry, A. | Deposit date: | 2009-06-24 | Release date: | 2009-07-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Characterization of the active site of S. aureus monofunctional glycosyltransferase (Mtg) by site-directed mutation and structural analysis of the protein complexed with moenomycin J.Struct.Biol., 167, 2009
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2X6I
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![BU of 2x6i by Molmil](/molmil-images/mine/2x6i) | THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PIK-90 | Descriptor: | N-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C] QUINAZOLIN-5-YL)NICOTINAMIDE, PHOSPHOTIDYLINOSITOL 3 KINASE 59F | Authors: | Miller, S, Tavshanjian, B, Oleksy, A, Perisic, O, Houseman, B.T, Shokat, K.M, Williams, R.L. | Deposit date: | 2010-02-17 | Release date: | 2010-04-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Science, 327, 2010
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2X6H
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![BU of 2x6h by Molmil](/molmil-images/mine/2x6h) | THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 | Descriptor: | PHOSPHOTIDYLINOSITOL 3 KINASE 59F | Authors: | Miller, S, Tavshanjian, B, Oleksy, A, Perisic, O, Houseman, B.T, Shokat, K.M, Williams, R.L. | Deposit date: | 2010-02-17 | Release date: | 2010-04-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Science, 327, 2010
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2X6K
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![BU of 2x6k by Molmil](/molmil-images/mine/2x6k) | THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PI-103 | Descriptor: | 3-(4-MORPHOLIN-4-YLPYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL)PHENOL, PHOSPHOTIDYLINOSITOL 3 KINASE 59F, SULFATE ION | Authors: | Miller, S, Tavshanjian, B, Oleksy, A, Perisic, O, Houseman, B.T, Shokat, K.M, Williams, R.L. | Deposit date: | 2010-02-17 | Release date: | 2010-04-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Science, 327, 2010
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2X6F
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![BU of 2x6f by Molmil](/molmil-images/mine/2x6f) | THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH 3-METHYLADENINE | Descriptor: | 6-AMINO-3-METHYLPURINE, PHOSPHOTIDYLINOSITOL 3 KINASE 59F | Authors: | Miller, S, Tavshanjian, B, Oleksy, A, Perisic, O, Houseman, B.T, Shokat, K.M, Williams, R.L. | Deposit date: | 2010-02-17 | Release date: | 2010-04-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Science, 327, 2010
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2X6J
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![BU of 2x6j by Molmil](/molmil-images/mine/2x6j) | THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PIK-93 | Descriptor: | N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE, PHOSPHOTIDYLINOSITOL 3 KINASE 59F | Authors: | Miller, S, Tavshanjian, B, Oleksy, A, Perisic, O, Houseman, B.T, Shokat, K.M, Williams, R.L. | Deposit date: | 2010-02-17 | Release date: | 2010-04-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Science, 327, 2010
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2L87
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![BU of 2l87 by Molmil](/molmil-images/mine/2l87) | The 27-residue N-terminus CCR5-peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide | Descriptor: | C-C chemokine receptor type 5 | Authors: | Schnur, E, Noah, E, Ayzenshtat, I, Sargsyan, H, Inui, T, Ding, F.X, Arshava, B, Sagi, Y, Kessler, N, Levy, R, Scherf, T, Naider, F, Anglister, J. | Deposit date: | 2011-01-06 | Release date: | 2011-07-27 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Conformation and Orientation of a 27-Residue CCR5 Peptide in a Ternary Complex with HIV-1 gp120 and a CD4-Mimic Peptide. J.Mol.Biol., 410, 2011
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2PAN
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![BU of 2pan by Molmil](/molmil-images/mine/2pan) | Crystal structure of E. coli glyoxylate carboligase | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, FLAVIN-ADENINE DINUCLEOTIDE, Glyoxylate carboligase, ... | Authors: | Kaplun, A, Chipman, D.M, Barak, Z, Vyazmensky, M, Shaanan, B. | Deposit date: | 2007-03-27 | Release date: | 2008-01-01 | Last modified: | 2021-08-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Glyoxylate carboligase lacks the canonical active site glutamate of thiamine-dependent enzymes. Nat.Chem.Biol., 4, 2008
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3RSW
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![BU of 3rsw by Molmil](/molmil-images/mine/3rsw) | Crystal Structure of Heart Fatty Acid Binding Protein (FABP3) | Descriptor: | Fatty acid-binding protein, heart | Authors: | Carney, D.F, Shankaran, B, Zwart, P.H, Stebbins, J.W, Prasad, G.S. | Deposit date: | 2011-05-02 | Release date: | 2012-05-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.599 Å) | Cite: | Crystal Structure of Heart Fatty Acid Binding Protein (FABP3) To be Published
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7L83
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![BU of 7l83 by Molmil](/molmil-images/mine/7l83) | NMR solution structure of Nav1.5 DIV S3b-S4a paddle motif in DPC micelle | Descriptor: | Sodium channel protein type 5 subunit alpha | Authors: | Hussein, A.K, Bhuiyan, M.H, Arshava, B, Zhuang, J, Poget, S.F. | Deposit date: | 2020-12-30 | Release date: | 2021-06-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR solution structure and analysis of isolated S3b-S4a motif of repeat IV of the human cardiac sodium channel Biorxiv, 2021
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5AJJ
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![BU of 5ajj by Molmil](/molmil-images/mine/5ajj) | |
5AJK
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![BU of 5ajk by Molmil](/molmil-images/mine/5ajk) | |
2J47
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![BU of 2j47 by Molmil](/molmil-images/mine/2j47) | Bacteroides thetaiotaomicron GH84 O-GlcNAcase in complex with a imidazole-pugnac hybrid inhibitor | Descriptor: | (5R,6R,7R,8S)-8-(ACETYLAMINO)-6,7-DIHYDROXY-5-(HYDROXYMETHYL)-N-PHENYL-1,5,6,7,8,8A-HEXAHYDROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXAMIDE, GLUCOSAMINIDASE, GLYCEROL | Authors: | Dennis, R.J, Davies, G.J. | Deposit date: | 2006-08-25 | Release date: | 2006-10-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Inhibition of O-Glcnacase by a Gluco-Configured Nagstatin and a Pugnac-Imidazole Hybrid Inhibitor Chem. Commun., 42, 2006
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5XHN
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![BU of 5xhn by Molmil](/molmil-images/mine/5xhn) | Crystal structure of Frog M-ferritin K104E mutant | Descriptor: | CHLORIDE ION, Ferritin, middle subunit, ... | Authors: | Jagdev, M.K, Vasudevan, D. | Deposit date: | 2017-04-21 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Surface charge dependent separation of modified and hybrid ferritin in native PAGE: Impact of lysine 104 Biochim. Biophys. Acta, 1865, 2017
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5XHM
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![BU of 5xhm by Molmil](/molmil-images/mine/5xhm) | Crystal structure of Frog M-ferritin D40A mutant | Descriptor: | CHLORIDE ION, Ferritin, middle subunit, ... | Authors: | Jagdev, M.K, Vasudevan, D. | Deposit date: | 2017-04-21 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Surface charge dependent separation of modified and hybrid ferritin in native PAGE: Impact of lysine 104 Biochim. Biophys. Acta, 1865, 2017
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