6H77

E1 enzyme for ubiquitin like protein activation in complex with UBL

Summary for 6H77

Entry DOI	10.2210/pdb6h77/pdb
Descriptor	Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-fold modifier 1, ADENOSINE-5'-TRIPHOSPHATE, ... (8 entities in total)
Functional Keywords	ubiquitin like protein activating enzyme, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	176816.67
Authors	Soudah, N.,Padala, P.,Hassouna, F.,Mashahreh, B.,Lebedev, A.A.,Isupov, M.N.,Cohen-Kfir, E.,Wiener, R. (deposition date: 2018-07-30, release date: 2018-10-31, Last modification date: 2024-01-17)
Primary citation	Soudah, N.,Padala, P.,Hassouna, F.,Kumar, M.,Mashahreh, B.,Lebedev, A.A.,Isupov, M.N.,Cohen-Kfir, E.,Wiener, R. An N-Terminal Extension to UBA5 Adenylation Domain Boosts UFM1 Activation: Isoform-Specific Differences in Ubiquitin-like Protein Activation. J.Mol.Biol., 431:463-478, 2019 Cited by PubMed: 30412706 DOI: 10.1016/j.jmb.2018.10.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation