Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3RHX
DownloadVisualize
BU of 3rhx by Molmil
Crystal structure of the catalytic domain of FGFR1 kinase in complex with ARQ 069
Descriptor: (6S)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amine, 1,2-ETHANEDIOL, Basic fibroblast growth factor receptor 1, ...
Authors:Eathiraj, S, Palma, R, Hirschi, M, Volckova, E, Nakuci, E, Castro, J, Chen, C.R, Chan, T.C, France, D.S, Ashwell, M.A.
Deposit date:2011-04-12
Release date:2011-05-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:A novel mode of protein kinase inhibition exploiting hydrophobic motifs of autoinhibited kinases: discovery of ATP-independent inhibitors of fibroblast growth factor receptor.
J.Biol.Chem., 286, 2011
4GMX
DownloadVisualize
BU of 4gmx by Molmil
Crystal structure of KPT185 in complex with CRM1-Ran-RanBP1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ...
Authors:Sun, Q, Chook, Y.M.
Deposit date:2012-08-16
Release date:2012-10-17
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia.
Blood, 120, 2012
7UEP
DownloadVisualize
BU of 7uep by Molmil
PANK3 complex structure with compound PZ-3860
Descriptor: 1,2-ETHANEDIOL, 1-[(2R)-4-(6-chloropyridazin-3-yl)-2-methylpiperazin-1-yl]-2-(4-cyclopropylphenyl)ethan-1-one, MAGNESIUM ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UEO
DownloadVisualize
BU of 7ueo by Molmil
PANK3 complex structure with compound PZ-3977
Descriptor: 1,2-ETHANEDIOL, 6-{4-[(4-cyclopropyl-2-fluorophenyl)acetyl]piperazin-1-yl}pyridazine-3-carbonitrile, MAGNESIUM ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UES
DownloadVisualize
BU of 7ues by Molmil
PANK3 complex structure with compound PZ-4202
Descriptor: MAGNESIUM ION, N-(4-{2-[4-(6-cyanopyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}phenyl)methanesulfonamide, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UER
DownloadVisualize
BU of 7uer by Molmil
PANK3 complex structure with compound PZ-4071
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MAGNESIUM ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UE4
DownloadVisualize
BU of 7ue4 by Molmil
PANK3 complex structure with compound PZ-3855
Descriptor: 1,2-ETHANEDIOL, 1-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-(4-cyclopropylphenyl)ethan-1-one, ACETATE ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-21
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UE3
DownloadVisualize
BU of 7ue3 by Molmil
PANK3 complex structure with compound PZ-3804
Descriptor: 1,2-ETHANEDIOL, 6-[4-({4-[(2R)-1-hydroxypropan-2-yl]phenyl}acetyl)piperazin-1-yl]pyridazine-3-carbonitrile, MAGNESIUM ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-21
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UEQ
DownloadVisualize
BU of 7ueq by Molmil
PANK3 complex structure with compound PZ-4061
Descriptor: 1-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-[4-(dimethylamino)phenyl]ethan-1-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UET
DownloadVisualize
BU of 7uet by Molmil
PANK3 complex structure with compound PZ-4140
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, N-(4-{2-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}phenyl)methanesulfonamide, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UE5
DownloadVisualize
BU of 7ue5 by Molmil
PANK3 complex structure with compound PZ-3741
Descriptor: 6-[4-({4-[(2R)-1,1,1-trifluoropropan-2-yl]phenyl}acetyl)piperazin-1-yl]pyridazine-3-carbonitrile, 6-[4-({4-[(2S)-1,1,1-trifluoropropan-2-yl]phenyl}acetyl)piperazin-1-yl]pyridazine-3-carbonitrile, MAGNESIUM ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-21
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UEY
DownloadVisualize
BU of 7uey by Molmil
PANK3 complex structure with compound PZ-4128
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, N-(4-{2-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}phenyl)-2-hydroxyacetamide, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UEV
DownloadVisualize
BU of 7uev by Molmil
PANK3 complex structure with compound PZ-4200
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UE7
DownloadVisualize
BU of 7ue7 by Molmil
PANK3 complex structure with compound PZ-3883
Descriptor: 1,2-ETHANEDIOL, 6-{4-[(4-cyclopropyl-3-fluorophenyl)acetyl]piperazin-1-yl}pyridazine-3-carbonitrile, ACETATE ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-21
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UEU
DownloadVisualize
BU of 7ueu by Molmil
PANK3 complex structure with compound PZ-4215
Descriptor: 1,2-ETHANEDIOL, AMP PHOSPHORAMIDATE, MAGNESIUM ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UEX
DownloadVisualize
BU of 7uex by Molmil
PANK3 complex structure with compound PZ-4127
Descriptor: 1,2-ETHANEDIOL, 2-(4-{2-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}anilino)-2-oxoethyl acetate, ACETATE ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-22
Release date:2023-03-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7UE6
DownloadVisualize
BU of 7ue6 by Molmil
PANK3 complex structure with compound PZ-3802
Descriptor: 1,2-ETHANEDIOL, 6-(4-{[5-fluoro-6-(propan-2-yl)pyridin-3-yl]acetyl}piperazin-1-yl)pyridazine-3-carbonitrile, ACETATE ION, ...
Authors:White, S.W, Yun, M, Lee, R.E.
Deposit date:2022-03-21
Release date:2023-04-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published
7S4E
DownloadVisualize
BU of 7s4e by Molmil
Crystal Structure of ligand ACBi1 in complex with bromodomain of human Smarca2 and pVHL:ElonginC:ElonginB complex
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Elongin-B, ...
Authors:MacPherson, D.J, Sherman, W.
Deposit date:2021-09-08
Release date:2022-10-05
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry.
Nat Commun, 13, 2022
5Y8X
DownloadVisualize
BU of 5y8x by Molmil
Crystal structure of Bacillus licheniformis Gamma glutamyl transpeptidase with Azaserine
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ...
Authors:Kumari, S, Goel, M, Pal, R, Gupta, R.
Deposit date:2017-08-21
Release date:2018-10-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structure of Bacillus licheniformis Gamma glutamyl transpeptidase with Azaserine
To Be Published
5FMN
DownloadVisualize
BU of 5fmn by Molmil
The nickel-responsive transcriptional regulator InrS
Descriptor: INRS
Authors:Foster, A.W, Patterson, C.J, Robinson, N.J, Pohl, E.
Deposit date:2015-11-06
Release date:2017-02-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A tight tunable range for Ni(II) sensing and buffering in cells.
Nat. Chem. Biol., 13, 2017
4F8K
DownloadVisualize
BU of 4f8k by Molmil
Molecular analysis of the interaction between the prostacyclin receptor and the first PDZ domain of PDZK1
Descriptor: Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Prostacyclin receptor
Authors:Kocher, O, Birrane, G, Kinsella, B.T, Mulvaney, E.P.
Deposit date:2012-05-17
Release date:2013-02-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Analysis of the Prostacyclin Receptor's Interaction with the PDZ1 Domain of Its Adaptor Protein PDZK1.
Plos One, 8, 2013
5XLU
DownloadVisualize
BU of 5xlu by Molmil
High Resolution Crystal Structure of Bacillus Licheniformis Gamma Glutamyl Transpeptidase with Acivicin
Descriptor: (2S)-AMINO[(5S)-3-CHLORO-4,5-DIHYDROISOXAZOL-5-YL]ACETIC ACID, CALCIUM ION, GLYCEROL, ...
Authors:Kumari, S, Goel, M, Gupta, R, Pal, R.
Deposit date:2017-05-11
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:High Resolution Crystal Structure of Bacillus Licheniformis Gamma Glutamyl Transpeptidase with Acivicin
To Be Published
3NGH
DownloadVisualize
BU of 3ngh by Molmil
Molecular Analysis of the Interaction of the HDL Receptor SR-BI with the Adaptor Protein PDZK1
Descriptor: PDZ domain-containing protein 1
Authors:Kocher, O, Birrane, G, Krieger, M, Ladias, J.A.
Deposit date:2010-06-11
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:In vitro and in vivo analysis of the binding of the C terminus of the HDL receptor scavenger receptor class B, type I (SR-BI), to the PDZ1 domain of its adaptor protein PDZK1.
J.Biol.Chem., 285, 2010
3R68
DownloadVisualize
BU of 3r68 by Molmil
Molecular Analysis of the PDZ3 domain of PDZK1
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ...
Authors:Kocher, O, Birrane, G, Krieger, M.
Deposit date:2011-03-21
Release date:2011-05-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I.
J.Biol.Chem., 286, 2011
3R69
DownloadVisualize
BU of 3r69 by Molmil
Molecular analysis of the interaction of the HDL-receptor SR-BI with the PDZ3 domain of its adaptor protein PDZK1
Descriptor: CITRIC ACID, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Scavenger receptor class B member 1
Authors:Kocher, O, Birrane, G, Krieger, M.
Deposit date:2011-03-21
Release date:2011-05-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.499 Å)
Cite:Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I.
J.Biol.Chem., 286, 2011

221371

數據於2024-06-19公開中

PDB statisticsPDBj update infoContact PDBjnumon