7UE3

PANK3 complex structure with compound PZ-3804

Summary for 7UE3

• Entry DOI: 10.2210/pdb7ue3/pdb
• Descriptor: Pantothenate kinase 3, 6-[4-({4-[(2R)-1-hydroxypropan-2-yl]phenyl}acetyl)piperazin-1-yl]pyridazine-3-carbonitrile, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total)
• Functional Keywords: pank, substrate, complex, transferase, pantothenate kinase, inhibitor, activator
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 43986.66

Authors

White, S.W.,Yun, M.,Lee, R.E. (deposition date: 2022-03-21, release date: 2023-03-29, Last modification date: 2023-10-25)

• Primary citation: Tangallapally, R.,Edwards, A.,Subramanian, C.,Sharma, L.K.,Yun, M.,White, S.W.,Jackowski, S.,Rock, C.O.,Lee, R.E.; Discovery of hPANK Activators with Improved Pharmacological Properties; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.56 Å)