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7UEO

PANK3 complex structure with compound PZ-3977

Summary for 7UEO
Entry DOI10.2210/pdb7ueo/pdb
DescriptorPantothenate kinase 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total)
Functional Keywordspank, substrate, complex, transferase, pantothenate kinase, inhibitor, activator
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight43145.79
Authors
White, S.W.,Yun, M.,Lee, R.E. (deposition date: 2022-03-22, release date: 2023-03-29, Last modification date: 2023-10-25)
Primary citationTangallapally, R.,Edwards, A.,Subramanian, C.,Sharma, L.K.,Yun, M.,White, S.W.,Jackowski, S.,Rock, C.O.,Lee, R.E.
Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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