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7UEP

PANK3 complex structure with compound PZ-3860

Summary for 7UEP
Entry DOI10.2210/pdb7uep/pdb
DescriptorPantothenate kinase 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (6 entities in total)
Functional Keywordspank, substrate, complex, transferase, pantothenate kinase, inhibitor, activator
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight43089.19
Authors
White, S.W.,Yun, M.,Lee, R.E. (deposition date: 2022-03-22, release date: 2023-03-29, Last modification date: 2023-10-25)
Primary citationTangallapally, R.,Edwards, A.,Subramanian, C.,Sharma, L.K.,Yun, M.,White, S.W.,Jackowski, S.,Rock, C.O.,Lee, R.E.
Discovery of hPANK Activators with Improved Pharmacological Properties
To Be Published,
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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