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8EC7
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BU of 8ec7 by Molmil
HnRNPA2 D290V LCD PM3
Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1
Authors:Eisenberg, D.S, Lu, J, Ge, P, Boyer, D.R.
Deposit date:2022-09-01
Release date:2023-09-06
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation.
J.Biol.Chem., 300, 2023
8E7E
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BU of 8e7e by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Afrin, S, Saelices, L.
Deposit date:2022-08-23
Release date:2023-08-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8E7J
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BU of 8e7j by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Saelices, L.
Deposit date:2022-08-24
Release date:2023-08-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
4GZR
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BU of 4gzr by Molmil
Crystal structure of the Mycobacterium tuberculosis H37Rv EsxOP (Rv2346c-Rv2347c) complex in space group C2221
Descriptor: ESAT-6-like protein 6, ESAT-6-like protein 7, SULFATE ION
Authors:Arbing, M.A, Chan, S, He, Q, Harris, L, Zhou, T.T, Kuo, E, Ahn, C.J, Eisenberg, D, TB Structural Genomics Consortium (TBSGC), Integrated Center for Structure and Function Innovation (ISFI)
Deposit date:2012-09-06
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.553 Å)
Cite:Heterologous expression of mycobacterial Esx complexes in Escherichia coli for structural studies is facilitated by the use of maltose binding protein fusions.
Plos One, 8, 2013
4E0M
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BU of 4e0m by Molmil
SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form I)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Cyclic pseudo-peptide SVQIVYK(ORN)EF(HAO)(4BF)K(ORN), PHOSPHATE ION
Authors:Zhao, M, Liu, C, Michael, S.R, Eisenberg, D.
Deposit date:2012-03-04
Release date:2013-02-13
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Out-of-register beta-sheets suggest a pathway to toxic amyloid aggregates
Proc.Natl.Acad.Sci.USA, 109, 2012
7QX4
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BU of 7qx4 by Molmil
mosquitocidal Cry11Aa determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7QX6
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BU of 7qx6 by Molmil
mosquitocidal Cry11Aa-E583Q determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7QX5
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BU of 7qx5 by Molmil
mosquitocidal Cry11Aa-Y449F determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7QX7
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BU of 7qx7 by Molmil
mosquitocidal Cry11Aa-F17Y determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
6AXZ
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BU of 6axz by Molmil
Segment from bank vole prion protein 168-176 QYNNQNNFV
Descriptor: Major prion protein
Authors:Glynn, C, Rodriguez, J.A, Boyer, D.R, Gallagher-Jones, M.
Deposit date:2017-09-07
Release date:2018-01-17
Last modified:2024-03-13
Method:ELECTRON CRYSTALLOGRAPHY (0.75 Å)
Cite:Sub-angstrom cryo-EM structure of a prion protofibril reveals a polar clasp.
Nat. Struct. Mol. Biol., 25, 2018
6BTK
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BU of 6btk by Molmil
Segment from bank vole prion protein 168-176 QYNNQNNFV
Descriptor: Major prion protein
Authors:Glynn, C, Rodriguez, J.A, Boyer, D.R, Gallagher-Jones, M.
Deposit date:2017-12-06
Release date:2018-01-17
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Sub-angstrom cryo-EM structure of a prion protofibril reveals a polar clasp.
Nat. Struct. Mol. Biol., 25, 2018
8TDN
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BU of 8tdn by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient-3, wild-type morphology
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Saelices, L.
Deposit date:2023-07-04
Release date:2023-12-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8TDO
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BU of 8tdo by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient-3, variant-type morphology
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Saelices, L.
Deposit date:2023-07-04
Release date:2023-12-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
4XFO
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BU of 4xfo by Molmil
Structure of an amyloid-forming segment TAVVTN from human Transthyretin
Descriptor: Amyloid-forming peptide TAVVTN
Authors:Saelices, L, Sawaya, M, Cascio, D, Eisenberg, D.S.
Deposit date:2014-12-27
Release date:2015-10-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4XFN
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BU of 4xfn by Molmil
Structure of an Amyloid forming peptide AEVVFT from Human Transthyretin
Descriptor: Amyloid forming peptide AEVVFT
Authors:Saelices, L, Sawaya, M, Cascio, D, Eisenberg, D.S.
Deposit date:2014-12-27
Release date:2015-10-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4YAY
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BU of 4yay by Molmil
XFEL structure of human Angiotensin Receptor
Descriptor: 5,7-diethyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-3,4-dihydro-1,6-naphthyridin-2(1H)-one, Soluble cytochrome b562,Type-1 angiotensin II receptor
Authors:Zhang, H, Unal, H, Gati, C, Han, G.W, Zatsepin, N.A, James, D, Wang, D, Nelson, G, Weierstall, U, Messerschmidt, M, Williams, G.J, Boutet, S, Yefanov, O.M, White, T.A, Liu, W, Ishchenko, A, Tirupula, K.C, Desnoyer, R, Sawaya, M.C, Xu, Q, Coe, J, Cornrad, C.E, Fromme, P, Stevens, R.C, Katritch, V, Karnik, S.S, Cherezov, V, GPCR Network (GPCR)
Deposit date:2015-02-18
Release date:2015-04-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.
Cell, 161, 2015
5E5Z
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BU of 5e5z by Molmil
Structure of the amyloid forming peptide LVHSSN (residues
Descriptor: LVHSSN (residues 16-21) from islet amyloid polypeptide
Authors:Soriaga, A.B, Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.664 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E61
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BU of 5e61 by Molmil
Structure of amyloid-forming peptide FGAILSS (residues 23-29) from islet amyloid polypeptide
Descriptor: FGAILSS (residues 23-29) from islet amyloid polypeptide
Authors:Soriaga, A.B, Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E5X
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BU of 5e5x by Molmil
Structure of the amyloid forming peptide ANFLVH (residues 13-18) from islet amyloid polypeptide
Descriptor: ANFLVH (residues 13-18) from islet amyloid polypeptide
Authors:Soriaga, A.B, Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
3LE4
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BU of 3le4 by Molmil
Crystal structure of the DGCR8 dimerization domain
Descriptor: Microprocessor complex subunit DGCR8
Authors:Senturia, R, Cascio, D, Sawaya, M, Guo, F.
Deposit date:2010-01-14
Release date:2010-07-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Structure of the dimerization domain of DiGeorge Critical Region 8
Protein Sci., 19, 2010
3LOZ
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BU of 3loz by Molmil
Crystal structure of Beta 2 Microglobulin amyloidogenic segment LSFSKD
Descriptor: Beta-2-microglobulin segment LSFSKD
Authors:Liu, C, Sawaya, M, Eisenberg, D.
Deposit date:2010-02-04
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Beta2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages.
Nat.Struct.Mol.Biol., 18, 2011
2CUU
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BU of 2cuu by Molmil
Crystal structure of spin labeled T4 Lysozyme (V131R1)
Descriptor: 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ...
Authors:Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L.
Deposit date:2005-05-28
Release date:2006-08-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural origin of weakly ordered nitroxide motion in spin-labeled proteins
Protein Sci., 18, 2009
4TL5
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BU of 4tl5 by Molmil
Crystal Structure of Human Transthyretin Ser85Pro Mutant
Descriptor: CHLORIDE ION, SODIUM ION, Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TKW
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BU of 4tkw by Molmil
Crystal Structure of Human Transthyretin Leu55Pro Mutant
Descriptor: Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-27
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015
4TL4
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BU of 4tl4 by Molmil
Crystal Structure of Human Transthyretin Val30Met Mutant
Descriptor: Transthyretin
Authors:Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S.
Deposit date:2014-05-28
Release date:2015-10-21
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Uncovering the Mechanism of Aggregation of Human Transthyretin.
J.Biol.Chem., 290, 2015

223532

數據於2024-08-07公開中

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