4YAY

XFEL structure of human Angiotensin Receptor

Summary for 4YAY

• Entry DOI: 10.2210/pdb4yay/pdb
• Descriptor: Soluble cytochrome b562,Type-1 angiotensin II receptor, 5,7-diethyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-3,4-dihydro-1,6-naphthyridin-2(1H)-one (2 entities in total)
• Functional Keywords: xfel, serial femtosecond crystallography, human angiotensin receptor at1r, bril, g protein-coupled receptor, gpcr, gpcr network, lipidic cubic phase, lcp, membrane protein, structural genomics, zd7155, angiotensin receptor blocker, room temperature, psi-biology
• Biological source: Escherichia coli; More
• Total number of polymer chains: 1
• Total formula weight: 47679.23

Authors

Zhang, H.,Unal, H.,Gati, C.,Han, G.W.,Zatsepin, N.A.,James, D.,Wang, D.,Nelson, G.,Weierstall, U.,Messerschmidt, M.,Williams, G.J.,Boutet, S.,Yefanov, O.M.,White, T.A.,Liu, W.,Ishchenko, A.,Tirupula, K.C.,Desnoyer, R.,Sawaya, M.C.,Xu, Q.,Coe, J.,Cornrad, C.E.,Fromme, P.,Stevens, R.C.,Katritch, V.,Karnik, S.S.,Cherezov, V.,GPCR Network (GPCR) (deposition date: 2015-02-18, release date: 2015-04-22, Last modification date: 2023-08-16)

• Primary citation: Zhang, H.,Unal, H.,Gati, C.,Han, G.W.,Liu, W.,Zatsepin, N.A.,James, D.,Wang, D.,Nelson, G.,Weierstall, U.,Sawaya, M.R.,Xu, Q.,Messerschmidt, M.,Williams, G.J.,Boutet, S.,Yefanov, O.M.,White, T.A.,Wang, C.,Ishchenko, A.,Tirupula, K.C.,Desnoyer, R.,Coe, J.,Conrad, C.E.,Fromme, P.,Stevens, R.C.,Katritch, V.,Karnik, S.S.,Cherezov, V.; Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.; Cell, 161:833-844, 2015; PubMed: 25913193; DOI: 10.1016/j.cell.2015.04.011

Experimental method

X-RAY DIFFRACTION (2.9 Å)