4YAY
XFEL structure of human Angiotensin Receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Soluble cytochrome b562,Type-1 angiotensin II receptor | polymer | 414 | 47240.7 | 1 | UniProt (P0ABE7) UniProt (P30556) Pfam (PF07361) Pfam (PF00001) | Escherichia coli | Cytochrome b-562,AT1AR,AT1BR,Angiotensin II type-1 receptor,AT1 |
| 2 | B (A) | 5,7-diethyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-3,4-dihydro-1,6-naphthyridin-2(1H)-one | non-polymer | 438.5 | 1 | Chemie (ZD7) |
Sequence modifications
A: 1001 - 1106 (UniProt: P0ABE7)
A: 12 - 319 (UniProt: P30556)
| PDB | External Database | Details |
|---|---|---|
| Trp 1007 | Met 29 | engineered mutation |
| Ile 1102 | Ile 124 | engineered mutation |
| Leu 1106 | Leu 128 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| - | Thr 7 | deletion |
| - | Glu 8 | deletion |
| - | Asp 9 | deletion |
| - | Gly 10 | deletion |
| - | Ile 11 | deletion |
| - | Lys 12 | deletion |
| - | Arg 13 | deletion |
| - | Ile 14 | deletion |
| - | Gln 15 | deletion |
| - | Asp 16 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47240.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 438.5 | |
| All* | Total formula weight | 47679.2 |
