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2KU7
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BU of 2ku7 by Molmil
Solution structure of MLL1 PHD3-Cyp33 RRM chimeric protein
Descriptor: MLL1 PHD3-Cyp33 RRM chimeric protein
Authors:Song, J, Wang, Z, Patel, D.
Deposit date:2010-02-12
Release date:2010-07-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
4QBR
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BU of 4qbr by Molmil
Crystal structure of DNMT3a ADD domain G550D mutant bound to H3 peptide
Descriptor: DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION
Authors:Wang, H, Li, H.
Deposit date:2014-05-08
Release date:2015-05-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
To be Published
2LA5
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BU of 2la5 by Molmil
RNA Duplex-Quadruplex Junction Complex with FMRP RGG peptide
Descriptor: Fragile X mental retardation 1 protein, RNA (36-MER)
Authors:Phan, A, Kuryavyi, V, Darnell, J, Serganov, A, Majumdar, A, Ilin, S, Darnell, R, Patel, D.
Deposit date:2011-03-03
Release date:2011-06-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction.
Nat.Struct.Mol.Biol., 18, 2011
4TN7
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BU of 4tn7 by Molmil
Crystal structure of mouse KDM2A-H3K36ME-NO complex
Descriptor: FE (III) ION, Lysine-specific demethylase 2A, NITRIC OXIDE, ...
Authors:Cheng, Z.
Deposit date:2014-06-03
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4N76
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BU of 4n76 by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA and cleaved target DNA with Mn2+
Descriptor: 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', Argonaute, ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-10-15
Release date:2014-01-15
Last modified:2025-02-12
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4N41
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BU of 4n41 by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA and 15-mer target DNA
Descriptor: 5'-D(*AP*AP*CP*CP*TP*AP*CP*TP*GP*CP*CP*TP*CP*G)-3', 5'-D(P*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*T*GP*TP*AP*TP*AP*GP*T)-3', ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-10-08
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.248 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NCB
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BU of 4ncb by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA and 19-mer target DNA with Mg2+
Descriptor: 5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*C)-3', 5'-D(*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-10-24
Release date:2014-01-15
Last modified:2025-02-12
Method:X-RAY DIFFRACTION (2.189 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NCA
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BU of 4nca by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA 19-mer and target DNA in the presence of Mg2+
Descriptor: 5'-D(*AP*CP*AP*AP*CP*C)-3', 5'-D(P*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-10-24
Release date:2014-01-15
Last modified:2025-02-12
Method:X-RAY DIFFRACTION (2.489 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
4N47
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BU of 4n47 by Molmil
Structure of Thermus thermophilus Argonaute bound to guide DNA and 12-mer target DNA
Descriptor: 5'-D(*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3', 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*TP*AP*GP*T)-3', Argonaute, ...
Authors:Sheng, G, Zhao, H, Wang, J, Rao, Y, Wang, Y.
Deposit date:2013-10-08
Release date:2014-01-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.823 Å)
Cite:Structure-based cleavage mechanism of Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage.
Proc.Natl.Acad.Sci.USA, 111, 2014
5ZUU
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BU of 5zuu by Molmil
Crystal structure of AtCPSF30 YTH domain in complex with 10mer m6A-modified RNA
Descriptor: 30-kDa cleavage and polyadenylation specificity factor 30, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Wu, B, Nie, H, Li, S, Patel, D.J.
Deposit date:2018-05-08
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis.
Mol Plant, 2021
4GIX
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BU of 4gix by Molmil
Crystal structure of human GLTP bound with 12:0 disulfatide
Descriptor: Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R, Ochoa-Lizarralde, B, Malinina, L.
Deposit date:2012-08-09
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GHS
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BU of 4ghs by Molmil
Crystal structure of human GLTP bound with 12:0 disulfatide (orthorombic form; two subunits in asymmetric unit)
Descriptor: Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R, Popov, A.N, Goni-de-Cerio, F, Cabo-Bilbao, A, Malinina, L.
Deposit date:2012-08-08
Release date:2013-06-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GHP
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BU of 4ghp by Molmil
Crystal Structure of D48V||A47D mutant of Human GLTP bound with 12:0 monosulfatide
Descriptor: Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R, Ochoa-Lizarralde, B, Popov, A.N, Malinina, L.
Deposit date:2012-08-08
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GJQ
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BU of 4gjq by Molmil
Crystal structure of human GLTP bound with 12:0 monosulfatide (orthorhombic form;two subunits in asymmetric unit)
Descriptor: (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, Glycolipid transfer protein, HEXANE
Authors:Cabo-Bilbao, A, Goni-de-Cerio, F, Samygina, V.R, Ochoa-Lizarralde, B, Popov, A.N, Malinina, L.
Deposit date:2012-08-10
Release date:2013-06-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GH0
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BU of 4gh0 by Molmil
Crystal structure of D48V mutant of human GLTP bound with 12:0 monosulfatide
Descriptor: Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide, PENTADECANE
Authors:Samygina, V.R, Cabo-Bilbao, A, Ochoa-Lizarralde, B, Popov, A.N, Malinina, L.
Deposit date:2012-08-07
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GVT
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BU of 4gvt by Molmil
Crystal structure of D48V mutant of human GLTP bound with 12:0 disulfatide (hexagonal form)
Descriptor: Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R, Cabo-Bilbao, A, Goni-de-Cerio, F, Popov, A.N, Malinina, L.
Deposit date:2012-08-31
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GXG
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BU of 4gxg by Molmil
Crystal structure of human GLTP bound with 12:0 monosulfatide (orthorhombic form; four subunits in asymmetric unit)
Descriptor: Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R, Cabo-Bilbao, A, Goni-de-Cerio, F, Popov, A.N, Malinina, L.
Deposit date:2012-09-04
Release date:2013-04-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4H2Z
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BU of 4h2z by Molmil
Crystal structure of human GLTP bound with 12:0 monosulfatide
Descriptor: Glycolipid transfer protein, N-{(2S,3R,4E)-3-hydroxy-1-[(3-O-sulfo-beta-D-galactopyranosyl)oxy]octadec-4-en-2-yl}dodecanamide, PENTADECANE, ...
Authors:Samygina, V.R, Ochoa-Lizarralde, B, Malinina, L.
Deposit date:2012-09-13
Release date:2013-04-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
4GXD
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BU of 4gxd by Molmil
Crystal structure of D48V mutant of human GLTP bound with 12:0 disulfatide
Descriptor: Glycolipid transfer protein, N-{(2S,3R,4E)-1-[(3,6-di-O-sulfo-beta-D-galactopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}dodecanamide
Authors:Samygina, V.R, Ochoa-Lizarralde, B, Popov, A.N, Malinina, L.
Deposit date:2012-09-04
Release date:2013-04-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into lipid-dependent reversible dimerization of human GLTP.
Acta Crystallogr.,Sect.D, 69, 2013
8C58
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BU of 8c58 by Molmil
CpG specific M.MpeI methyltransferase crystallized in the presence of 5-hydroxycytosine and 5-methylcytosine containing dsDNA
Descriptor: CARBONATE ION, Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(5OC)P*GP*CP*TP*GP*AP*A)-3'), ...
Authors:Wojciechowski, M, Czapinska, H, Krwawicz, J, Rafalski, D, Bochtler, M.
Deposit date:2023-01-06
Release date:2024-01-17
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Cytosine analogues as DNA methyltransferase substrates.
Nucleic Acids Res., 52, 2024
8C59
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BU of 8c59 by Molmil
CpG specific M.MpeI methyltransferase crystallized in the presence of 5-bromocytosine (converted to 5mC) and 5-methylcytosine containing dsDNA
Descriptor: CARBONATE ION, CITRIC ACID, Cytosine-specific methyltransferase, ...
Authors:Wojciechowski, M, Czapinska, H, Krwawicz, J, Rafalski, D, Bochtler, M.
Deposit date:2023-01-06
Release date:2024-01-17
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cytosine analogues as DNA methyltransferase substrates.
Nucleic Acids Res., 52, 2024
8C57
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BU of 8c57 by Molmil
CpG specific M.MpeI methyltransferase crystallized in the presence of 5,6-dihydro-5-azacytosine (converted to 5m-dhaC) and 5-methylcytosine containing dsDNA
Descriptor: CARBONATE ION, Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(5MA)P*GP*CP*TP*GP*AP*A)-3'), ...
Authors:Wojciechowski, M, Czapinska, H, Krwawicz, J, Rafalski, D, Bochtler, M.
Deposit date:2023-01-06
Release date:2024-01-17
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Cytosine analogues as DNA methyltransferase substrates.
Nucleic Acids Res., 52, 2024
8C56
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BU of 8c56 by Molmil
CpG specific M.MpeI methyltransferase crystallized in the presence of 2'-deoxy-5-methylzebularine (5mZ) and 5-methylcytosine containing dsDNA
Descriptor: Cytosine-specific methyltransferase, DNA (5'-D(*CP*CP*AP*CP*AP*TP*GP*(5PY)P*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*CP*AP*GP*(5CM)P*GP*CP*AP*TP*GP*TP*G)-3'), ...
Authors:Wojciechowski, M, Czapinska, H, Krwawicz, J, Rafalski, D, Bochtler, M.
Deposit date:2023-01-06
Release date:2024-01-17
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Cytosine analogues as DNA methyltransferase substrates.
Nucleic Acids Res., 52, 2024
4KSA
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BU of 4ksa by Molmil
Crystal Structure of Malonyl-CoA decarboxylase from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR127
Descriptor: MAGNESIUM ION, Malonyl-CoA decarboxylase
Authors:Forouhar, F, Neely, H, Seetharaman, J, Sahdev, S, Xiao, R, Patel, D.J, Ciccosanti, C, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2013-05-17
Release date:2013-06-19
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of malonyl-coenzyme a decarboxylase provide insights into its catalytic mechanism and disease-causing mutations.
Structure, 21, 2013
9C3G
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BU of 9c3g by Molmil
human cGAS core domain (K427E/K428E) bound to Cladophorol A
Descriptor: Cyclic GMP-AMP synthase, ZINC ION, cladophorol A
Authors:Kissai, M, Stanfield, R.L, Lairson, L.L.
Deposit date:2024-05-31
Release date:2025-03-05
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Cladophorol-A is an inhibitor of cyclic GMP-AMP synthase.
Bioorg.Med.Chem.Lett., 115, 2025

238582

數據於2025-07-09公開中

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