4KSA

Crystal Structure of Malonyl-CoA decarboxylase from Rhodopseudomonas palustris, Northeast Structural Genomics Consortium Target RpR127

Summary for 4KSA

• Entry DOI: 10.2210/pdb4ksa/pdb
• Related: 4KS9 4KSF
• Descriptor: Malonyl-CoA decarboxylase, MAGNESIUM ION (3 entities in total)
• Functional Keywords: nesgc, structural genomics, psi-biology, northeast structural genomics consortium, alpha-beta two-domained protein, lyase
• Biological source: Rhodopseudomonas palustris
• Total number of polymer chains: 4
• Total formula weight: 201612.53

Authors

Forouhar, F.,Neely, H.,Seetharaman, J.,Sahdev, S.,Xiao, R.,Patel, D.J.,Ciccosanti, C.,Wang, D.,Everett, J.K.,Acton, T.B.,Montelione, G.T.,Hunt, J.F.,Tong, L.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2013-05-17, release date: 2013-06-19, Last modification date: 2017-11-15)

• Primary citation: Froese, D.S.,Forouhar, F.,Tran, T.H.,Vollmar, M.,Kim, Y.S.,Lew, S.,Neely, H.,Seetharaman, J.,Shen, Y.,Xiao, R.,Acton, T.B.,Everett, J.K.,Cannone, G.,Puranik, S.,Savitsky, P.,Krojer, T.,Pilka, E.S.,Kiyani, W.,Lee, W.H.,Marsden, B.D.,von Delft, F.,Allerston, C.K.,Spagnolo, L.,Gileadi, O.,Montelione, G.T.,Oppermann, U.,Yue, W.W.,Tong, L.; Crystal structures of malonyl-coenzyme a decarboxylase provide insights into its catalytic mechanism and disease-causing mutations.; Structure, 21:1182-1192, 2013; PubMed: 23791943; DOI: 10.1016/j.str.2013.05.001

Experimental method

X-RAY DIFFRACTION (2.7 Å)